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Electron Microscopy
3.68Å resolution

Structure of the human endogenous PCNA-FEN1 complex - State A

Released:
Source organism: Homo sapiens
Related structures: EMD-39342

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-281319 (preferred)
Entry contents:
2 distinct polypeptide molecules
4 distinct DNA molecules
Macromolecules (6 distinct):
Proliferating cell nuclear antigen Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
Flap endonuclease 1 Chain: D
Molecule details ›
Chain: D
Length: 380 amino acids
Theoretical weight: 42.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P39748 (Residues: 1-380; Coverage: 100%)
Gene names: FEN1, RAD2
Sequence domains:
upstream DNA chain J Chain: J
parent strand chain E Chain: E
downstream DNA chain F Chain: F
5 prime DNA Chain: H

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.68Å
Relevant EMDB volumes: EMD-39342
Expression system: Homo sapiens