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structure of phage T6 topoisomerase II central domain bound with DNA

Source organisms:
Biochemical function: DNA negative supercoiling activity
Biological process: DNA topological change
Cellular component: protein-containing complex

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EC 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing)

Reaction catalysed:
ATP-dependent breakage, passage and rejoining of double-stranded DNA
Systematic name:
DNA topoisomerase (ATP-hydrolyzing)
Alternative Name(s):
  • DNA gyrase
  • DNA topoisomerase II
  • Type II DNA topoisomerase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00204
Domain description: DNA gyrase B
Occurring in:
  1. DNA topoisomerase (ATP-hydrolyzing)
The deposited structure of PDB entry 8ylu contains 2 copies of Pfam domain PF00204 (DNA gyrase B) in DNA topoisomerase (ATP-hydrolyzing). Showing 1 copy in chain C (this domain is out of the observed residue ranges!).

PF02518
Domain description: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Occurring in:
  1. DNA topoisomerase (ATP-hydrolyzing)
The deposited structure of PDB entry 8ylu contains 2 copies of Pfam domain PF02518 (Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase) in DNA topoisomerase (ATP-hydrolyzing). Showing 1 copy in chain C (this domain is out of the observed residue ranges!).

PF00521
Domain description: DNA gyrase/topoisomerase IV, subunit A
Occurring in:
  1. DNA topoisomerase medium subunit
The deposited structure of PDB entry 8ylu contains 2 copies of Pfam domain PF00521 (DNA gyrase/topoisomerase IV, subunit A) in DNA topoisomerase medium subunit. Showing 1 copy in chain A.

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