› 8yth

X-ray diffraction
2.4Å resolution

Crystal structures of human IRF2BP2 RING domain in complex with ZBTB16 peptide

Released:
DOI: 10.2210/pdb8yth/pdb
PDB entry 8yth coloured by chain, front view.
PDB entry 8yth coloured by chain, side view.
PDB entry 8yth coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang GC, Ding JP

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-554719 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interferon regulatory factor 2-binding protein 2 Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 8.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7Z5L9 (Residues: 497-578; Coverage: 14%)
Gene name: IRF2BP2
Zinc finger and BTB domain-containing protein 16 Chain: B
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 821 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q05516 (Residues: 285-292; Coverage: 1%)
Gene names: PLZF, ZBTB16, ZNF145

Ligands and Environments

1 bound ligand:
Ligand ZN 3 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P64
Unit cell:
a: 47.315Å b: 47.315Å c: 57.489Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.245 0.243 0.281
Expression systems:
  • Escherichia coli
  • Not provided

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