8ywg

Electron Microscopy
3.28Å resolution

The structure of ASFV DNA polymerase in apo state

Released:
Source organism: African swine fever virus
Primary publication:
Cryo-EM structure of DNA polymerase of African swine fever virus.
Nucleic Acids Res 52 10717-10729 (2024)
PMID: 39189451
Related structures: EMD-39632

Function and Biology Details

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-286609 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase beta Chain: A
Molecule details ›
Chain: A
Length: 1206 amino acids
Theoretical weight: 139.72 KDa
Source organism: African swine fever virus
Expression system: Spodoptera
UniProt:
  • Canonical: P42489 (Residues: 1-1211; Coverage: 100%)
Gene names: Ba71V-90, DPOL, G1207R, G1211R
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.28Å
Relevant EMDB volumes: EMD-39632
Expression system: Spodoptera