› 8z27

Electron Microscopy
2.86Å resolution

The structure of TGEV RBD and dog APN complex

Released:
DOI: 10.2210/pdb8z27/pdb
PDB entry 8z27 coloured by chain, front view.
PDB entry 8z27 coloured by chain, side view.
PDB entry 8z27 coloured by chain, top view.
Source organisms:
Entry authors: Sun JQ, Niu S
Related structures: EMD-39743

Function and Biology Details

Reaction catalysed: 
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-282280 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Spike glycoprotein Chain: a
Molecule details ›
Chain: a
Length: 175 amino acids
Theoretical weight: 19.36 KDa
Source organism: TGEV virulent Purdue
Expression system: Homo sapiens
UniProt:
  • Canonical: Q0PKZ5 (Residues: 497-671; Coverage: 12%)
Gene name: S
Sequence domains: Coronavirus spike glycoprotein S1
Aminopeptidase N Chain: b
Molecule details ›
Chain: b
Length: 943 amino acids
Theoretical weight: 107 KDa
Source organism: Canis lupus familiaris
Expression system: Homo sapiens
UniProt:
  • Canonical: P79143 (Residues: 36-975; Coverage: 96%)
Gene name: ANPEP
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.86Å
Relevant EMDB volumes: EMD-39743
Expression system: Homo sapiens

Quick links