› 8zgd

X-ray diffraction
2.05Å resolution

The Crystal Structure of the NLRP1_LRR domain from Biortus.

Released:
DOI: 10.2210/pdb8zgd/pdb
PDB entry 8zgd coloured by chain, front view.
PDB entry 8zgd coloured by chain, side view.
PDB entry 8zgd coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang F, Cheng W, Yuan Z, Qi J, Pan W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189873 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NACHT, LRR and PYD domains-containing protein 1, N-terminus Chain: A
Molecule details ›
Chain: A
Length: 200 amino acids
Theoretical weight: 22.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9C000 (Residues: 791-990; Coverage: 14%)
Gene names: CARD7, DEFCAP, KIAA0926, NAC, NALP1, NLRP1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: P6122
Unit cell:
a: 84.582Å b: 84.582Å c: 132.495Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.176 0.221
Expression system: Escherichia coli BL21(DE3)

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