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Electron Microscopy
3.06Å resolution

Cryo-EM structure of kisspeptin receptor bound to KP-10

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-273826 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
KiSS-1 receptor Chain: R
Molecule details ›
Chain: R
Length: 512 amino acids
Theoretical weight: 55.95 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Kisspeptin-10 Chain: L
Molecule details ›
Chain: L
Length: 11 amino acids
Theoretical weight: 1.38 KDa
Source organism: synthetic construct
Expression system: Not provided
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
scFv16 Chain: S
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: G
Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding protein G(q) subunit alpha Chain: A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.06Å
Relevant EMDB volumes: EMD-60141
Expression systems:
  • Trichoplusia ni
  • Not provided
  • Spodoptera frugiperda