› 8zjv

X-ray diffraction
1.8Å resolution

Crystal Structure of the ERK2 complexed with 5-Iodotubercidin

Released:
DOI: 10.2210/pdb8zjv/pdb
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PDB entry 8zjv coloured by chain, front view.
PDB entry 8zjv coloured by chain, side view.
PDB entry 8zjv coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Yang Y, Fu L, Chen R, Cheng H, Sun X

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-151230 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 1 Chain: A
Molecule details ›
Chain: A
Length: 351 amino acids
Theoretical weight: 40.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P28482 (Residues: 10-360; Coverage: 98%)
Gene names: ERK2, MAPK1, PRKM1, PRKM2
Sequence domains: Protein kinase domain

Ligands and Environments

4 bound ligands:
Ligand 5ID 1 x 5ID
Ligand EDO 3 x EDO
Ligand SO4 4 x SO4
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL02U1
Spacegroup: P3221
Unit cell:
a: 96.979Å b: 96.979Å c: 95.53Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.192 0.19 0.22
Expression system: Escherichia coli

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