› 8zkn

Electron Microscopy
3.06Å resolution

CryoEM structure of Thyroid Hormone Transporter MCT8 bound with silychristin

Released:
DOI: 10.2210/pdb8zkn/pdb
PDB entry 8zkn coloured by chain, front view.
PDB entry 8zkn coloured by chain, side view.
PDB entry 8zkn coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tan J, Xiao Y, Kong F, Zhu A, Qian J, Yan C
Related structures: EMD-60200

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-291309 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Monocarboxylate transporter 8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 539 amino acids
Theoretical weight: 59.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P36021 (Residues: 1-539; Coverage: 100%)
Gene names: MCT7, MCT8, SLC16A2, XPCT
Sequence domains: Major Facilitator Superfamily

Ligands and Environments

3 bound ligands:
Ligand A1IET 2 x A1IET
Ligand PC1 1 x PC1
Ligand DU0 2 x DU0
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.06Å
Relevant EMDB volumes: EMD-60200
Expression system: Homo sapiens

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