› 8zpa

X-ray diffraction
2.59Å resolution

Crystal structure of a HSA/probe complex

Released:
DOI: 10.2210/pdb8zpa/pdb
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PDB entry 8zpa coloured by chain, front view.
PDB entry 8zpa coloured by chain, side view.
PDB entry 8zpa coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Conversion of albumin into a BODIPY-like photosensitizer by a flick reaction, tumor accumulation and photodynamic therapy.
Yang M, Kim Y, Youn SY, Jeong H, Shirbhate ME, Uhm C, Kim G, Nam KT, Cha SS, Kim KM, Yoon J
Biomaterials 313 122792 (2025)
PMID: 39226652

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136176 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Albumin Chain: A
Molecule details ›
Chain: A
Length: 591 amino acids
Theoretical weight: 67.35 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P02768 (Residues: 19-609; Coverage: 100%)
Gene names: ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341
Sequence domains: Serum albumin family

Ligands and Environments

4 bound ligands:
Ligand UI8 1 x UI8
Ligand EDO 3 x EDO
Ligand PLM 1 x PLM
Ligand STE 1 x STE
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: C2
Unit cell:
a: 185.705Å b: 38.441Å c: 93.29Å
α: 90° β: 103.92° γ: 90°
R-values:
R R work R free
0.24 0.237 0.266

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