› 8zwm

Electron Microscopy
3.2Å resolution

Heparin bound Tau fibril polymorph 4

Released:
DOI: 10.2210/pdb8zwm/pdb
PDB entry 8zwm coloured by chain, front view.
PDB entry 8zwm coloured by chain, side view.
PDB entry 8zwm coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tao YQ, Liu C, Li D
Related structures: EMD-60533

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145403 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated protein tau Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 441 amino acids
Theoretical weight: 45.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10636 (Residues: 1-758; Coverage: 58%)
  • Best match: P10636-8 (Residues: 1-441)
Gene names: MAPT, MAPTL, MTBT1, TAU
Sequence domains: Tau and MAP protein, tubulin-binding repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-60533
Expression system: Escherichia coli

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