› 8zwv

X-ray diffraction
1.5Å resolution

The Crystal Structure of carbonic anhydrase II from Biortus.

Released:
DOI: 10.2210/pdb8zwv/pdb
PDB entry 8zwv coloured by chain, front view.
PDB entry 8zwv coloured by chain, side view.
PDB entry 8zwv coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wang F, Cheng W, Lv Z, Ju C, Bao C

Function and Biology Details

Reactions catalysed: 
H(2)CO(3) = CO(2) + H(2)O
Urea = cyanamide + H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133681 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 2 Chain: A
Molecule details ›
Chain: A
Length: 261 amino acids
Theoretical weight: 29.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00918 (Residues: 1-260; Coverage: 100%)
Gene name: CA2
Sequence domains: Eukaryotic-type carbonic anhydrase

Ligands and Environments

3 bound ligands:
Ligand V7Z 1 x V7Z
Ligand ZN 1 x ZN
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 42.525Å b: 72.204Å c: 74.059Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.154 0.152 0.187
Expression system: Escherichia coli BL21(DE3)

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