› 9c0v

X-ray diffraction
3.5Å resolution

Crystal structure of chimeric hemagglutinin cH5/1 in complex with broad protective antibody 3E1

Released:
DOI: 10.2210/pdb9c0v/pdb
Model geometry
Fit model/data
PDB entry 9c0v coloured by chain, front view.
PDB entry 9c0v coloured by chain, side view.
PDB entry 9c0v coloured by chain, top view.
Source organisms:
Entry authors: Nguyen TKY, Wilson IA

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-286496 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin Chains: A, B
Molecule details ›
Chains: A, B
Length: 541 amino acids
Theoretical weight: 60.96 KDa
Source organism: Influenza A virus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: H8PCW9 (Residues: 17-525; Coverage: 90%)
Gene name: HA
Sequence domains: Haemagglutinin
Antibody 3E1 Fab heavy chain Chain: H
Molecule details ›
Chain: H
Length: 224 amino acids
Theoretical weight: 23.87 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Antibody 3E1 Fab light chain Chain: L

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRL BEAMLINE BL12-1
Spacegroup: I213
Unit cell:
a: 241.491Å b: 241.491Å c: 241.491Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.294 0.292 0.321
Expression systems:
  • Trichoplusia ni
  • Cricetulus griseus

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