› 9jn0

Electron Microscopy
2.84Å resolution

Cryo-EM structure of a human-infecting bovine influenza H5N1 hemagglutinin complexed with human receptor analog LSTc

Released:
DOI: 10.2210/pdb9jn0/pdb
PDB entry 9jn0 coloured by chain, front view.
PDB entry 9jn0 coloured by chain, side view.
PDB entry 9jn0 coloured by chain, top view.
Source organism: Influenza A virus (A/Indonesia/5/2005(H5N1))
Primary publication:
Receptor binding, structure, and tissue tropism of cattle-infecting H5N1 avian influenza virus hemagglutinin.
Song H, Hao T, Han P, Wang H, Zhang X, Li X, Wang Y, Chen J, Li Y, Jin X, Duan X, Zhang W, Bi Y, Jin R, Sun L, Wang N, Gao GF
Cell (2025)
PMID: 39848246
Related structures: EMD-61617

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-290093 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Hemagglutinin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 506 amino acids
Theoretical weight: 57.7 KDa
Source organism: Influenza A virus (A/Indonesia/5/2005(H5N1))
Expression system: Spodoptera frugiperda

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, GAL, SIA
Carbohydrate polymer
1 bound ligand:
Ligand NAG 9 x NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.84Å
Relevant EMDB volumes: EMD-61617
Expression system: Spodoptera frugiperda

Quick links

Citations

1 citations in other articles

Editorial: Characteristics and prevention of the emerging avian influenza A viruses in birds and mammals.
Sui et al. (2025)