› 9avw

X-ray diffraction
1.75Å resolution

Structure of TAB2 NZF domain bound to K6 / Lys6-linked diubiquitin

Released:
DOI: 10.2210/pdb9avw/pdb
PDB entry 9avw coloured by chain, front view.
PDB entry 9avw coloured by chain, side view.
PDB entry 9avw coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Michel MA, Scutts S, Komander D

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-272697 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin Chains: A, B
Molecule details ›
Chains: A, B
Length: 152 amino acids
Theoretical weight: 17.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CG47 (Residues: 77-228; Coverage: 66%)
Gene name: UBB
Sequence domains: Ubiquitin family
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 Chain: C
Molecule details ›
Chain: C
Length: 31 amino acids
Theoretical weight: 3.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NYJ8 (Residues: 663-693; Coverage: 5%)
Gene names: KIAA0733, MAP3K7IP2, TAB2

Ligands and Environments

2 bound ligands:
Ligand SO4 6 x SO4
Ligand ZN 1 x ZN
1 modified residue:
Ligand SEP 2 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P6522
Unit cell:
a: 89.663Å b: 89.663Å c: 86.12Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.194 0.222
Expression system: Escherichia coli

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