› 9b9t

X-ray diffraction
2.05Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-280847 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
WD repeat-containing protein 5 Chain: A
Molecule details ›
Chain: A
Length: 329 amino acids
Theoretical weight: 36.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: P61964 (Residues: 24-334; Coverage: 93%)
Gene names: BIG3, WDR5
Sequence domains: WD domain, G-beta repeat
DDB1- and CUL4-associated factor 1 Chain: B
Molecule details ›
Chain: B
Length: 338 amino acids
Theoretical weight: 38.3 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9Y4B6 (Residues: 1080-1390; Coverage: 21%)
Gene names: DCAF1, KIAA0800, RIP, VPRBP

Ligands and Environments

1 bound ligand:
Ligand A1ANM 1 x A1ANM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08B1-1
Spacegroup: P212121
Unit cell:
a: 79.863Å b: 83.714Å c: 130.126Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.186 0.196
Expression systems:
  • Escherichia coli 'BL21-Gold(DE3)pLysS AG'
  • Spodoptera frugiperda

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