Function and Biology

80S ribosome bound with angiogenin and complex of eEF1A and Ala-tRNAAla

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase

Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Systematic name:
DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase
Alternative Name(s):
  • AP endonuclease class I
  • AP lyase
  • AP site-DNA 5'-phosphomonoester-lyase
  • Deoxyribonuclease (apurinic or apyrimidinic)
  • E. coli endonuclease III
  • E.coli endonuclease III
  • Endodeoxyribonuclease (apurinic or apyrimidinic)
  • Micrococcus luteus UV endonuclease
  • Phage-T(4) UV endonuclease
  • Phage-T4 UV endonuclease
  • X-ray endonuclease III

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Rfam RNA families (Rfam)
RF01960
Domain description: Eukaryotic small subunit ribosomal RNA
Occurring in:
  1. 18S Ribosomal RNA
The deposited structure of PDB entry 9bdp contains 1 copy of Rfam domain RF01960 (Eukaryotic small subunit ribosomal RNA) in 18S Ribosomal RNA. Showing 1 copy in chain A [auth A18S].

RF02543
Domain description: Eukaryotic large subunit ribosomal RNA
Occurring in:
  1. 28S ribosomal RNA
The deposited structure of PDB entry 9bdp contains 1 copy of Rfam domain RF02543 (Eukaryotic large subunit ribosomal RNA) in 28S ribosomal RNA. Showing 1 copy in chain B [auth A28S].

RF00002
Domain description: 5.8S ribosomal RNA
Occurring in:
  1. 5.8S ribosomal RNA
The deposited structure of PDB entry 9bdp contains 1 copy of Rfam domain RF00002 (5.8S ribosomal RNA) in 5.8S ribosomal RNA. Showing 1 copy in chain C [auth A58S].

RF00001
Domain description: 5S ribosomal RNA
Occurring in:
  1. 5S ribosomal RNA
The deposited structure of PDB entry 9bdp contains 1 copy of Rfam domain RF00001 (5S ribosomal RNA) in 5S ribosomal RNA. Showing 1 copy in chain D [auth A5S].

RF00005
Domain description: tRNA
Occurring in:
  1. tRNAfMet
  2. tRNAAla
The deposited structure of PDB entry 9bdp contains 2 copies of Rfam domain RF00005 (tRNA) in tRNAfMet. Showing 1 copy in chain EC [auth ETRN].
The deposited structure of PDB entry 9bdp contains 1 copy of Rfam domain RF00005 (tRNA) in tRNAAla. Showing 1 copy in chain HC [auth TIRN].