EC 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase
Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Systematic name:
DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase
Alternative Name(s):
- AP endonuclease class I
- AP lyase
- AP site-DNA 5'-phosphomonoester-lyase
- Deoxyribonuclease (apurinic or apyrimidinic)
- E. coli endonuclease III
- E.coli endonuclease III
- Endodeoxyribonuclease (apurinic or apyrimidinic)
- Micrococcus luteus UV endonuclease
- Phage-T(4) UV endonuclease
- Phage-T4 UV endonuclease
- X-ray endonuclease III