› 9bet

Solution NMR

Structure of the human CD33 transmembrane domain

Released:
DOI: 10.2210/pdb9bet/pdb
PDB entry 9bet coloured by chain, ensemble of 21 models, front view.
PDB entry 9bet coloured by chain, ensemble of 21 models, side view.
PDB entry 9bet coloured by chain, ensemble of 21 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the CD33 Receptor and Implications for the Siglec Family.
Vu HN, Situ AJ, Dai X, Ulmer TS
Biochemistry (2025)
PMID: 40067740

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148857 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myeloid cell surface antigen CD33 Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: P20138 (Residues: 251-291; Coverage: 12%)
Gene names: CD33, SIGLEC3

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 35%
Refinement method: simulated annealing
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

Quick links