› 9biu

Electron Microscopy
2.9Å resolution

Cryo-EM structure of the mammalian peptide transporter PepT2 bound to cloxacillin, pose 2

Released:
DOI: 10.2210/pdb9biu/pdb
PDB entry 9biu coloured by chain, front view.
PDB entry 9biu coloured by chain, side view.
PDB entry 9biu coloured by chain, top view.
Source organisms:
Entry authors: Parker JL, Deme JC, Lea SM, Newstead S
Related structures: EMD-44602

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-247459 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Solute carrier family 15 member 2 Chain: A
Molecule details ›
Chain: A
Length: 738 amino acids
Theoretical weight: 82.48 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q63424 (Residues: 1-729; Coverage: 100%)
Gene names: Pept2, Slc15a2
Sequence domains: POT family
nanobody Chain: B
Molecule details ›
Chain: B
Length: 131 amino acids
Theoretical weight: 14.49 KDa
Source organism: Lama glama

Ligands and Environments

1 bound ligand:
Ligand CXN 1 x CXN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.9Å
Relevant EMDB volumes: EMD-44602
Expression system: Homo sapiens

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