› 9bq2

Electron Microscopy
3.5Å resolution

Structure of the flotillin complex in a native membrane environment

Released:
DOI: 10.2210/pdb9bq2/pdb
PDB entry 9bq2 coloured by chain, front view.
PDB entry 9bq2 coloured by chain, side view.
PDB entry 9bq2 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the flotillin complex in a native membrane environment.
Fu Z, MacKinnon R
Proc Natl Acad Sci U S A 121 e2409334121 (2024)
PMID: 38985763
Related structures: EMD-44792

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 44-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-247321 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Flotillin Chain: A
Molecule details ›
Chain: A
Length: 402 amino acids
Theoretical weight: 44.57 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: J3QLD9 (Residues: 1-402; Coverage: 94%)
Gene names: FLOT2, hCG_1998851
Sequence domains: SPFH domain / Band 7 family
Flotillin-1 Chain: B
Molecule details ›
Chain: B
Length: 422 amino acids
Theoretical weight: 46.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O75955 (Residues: 1-422; Coverage: 99%)
Gene name: FLOT1
Sequence domains: SPFH domain / Band 7 family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-44792

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