› 9c47

Electron Microscopy
3.4Å resolution

TRRAP module of the human TIP60 complex

Released:
DOI: 10.2210/pdb9c47/pdb
PDB entry 9c47 coloured by chain, front view.
PDB entry 9c47 coloured by chain, side view.
PDB entry 9c47 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Yang Z, Mameri A, Cattoglio C, Lachance C, Florez Ariza AJ, Luo J, Humbert J, Sudarshan D, Banerjea A, Galloy M, Fradet-Turcotte A, Lambert JP, Ranish JA, Côté J, Nogales E
Science eadl5816 (2024)
PMID: 39088653
Related structures: EMD-45176

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-275267 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Transformation/transcription domain-associated protein Chain: C
Molecule details ›
Chain: C
Length: 3859 amino acids
Theoretical weight: 438.14 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y4A5 (Residues: 1-3859; Coverage: 100%)
Gene names: PAF400, TRRAP
Sequence domains:
E1A-binding protein p400 Chain: G
Molecule details ›
Chain: G
Length: 3159 amino acids
Theoretical weight: 343.87 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96L91 (Residues: 1-3159; Coverage: 100%)
Gene names: CAGH32, EP400, KIAA1498, KIAA1818, TNRC12
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.4Å
Relevant EMDB volumes: EMD-45176

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