9c7u

Electron Microscopy
3.65Å resolution

Structure of the human truncated BOS complex in GDN

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-280212 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
BOS complex subunit NCLN Chain: A
Molecule details ›
Chain: A
Length: 563 amino acids
Theoretical weight: 63.05 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q969V3 (Residues: 1-563; Coverage: 100%)
Gene name: NCLN
Sequence domains: Peptidase family M28
BOS complex subunit NOMO2 Chain: B
Molecule details ›
Chain: B
Length: 386 amino acids
Theoretical weight: 42.39 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q5JPE7 (Residues: 1-1222; Coverage: 29%)
Gene name: NOMO2
Sequence domains: Prealbumin-like fold domain
BOS complex subunit TMEM147 Chain: C
Molecule details ›
Chain: C
Length: 224 amino acids
Theoretical weight: 25.28 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9BVK8 (Residues: 1-224; Coverage: 100%)
Gene name: TMEM147
Sequence domains: Predicted membrane protein (DUF2053)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.65Å
Relevant EMDB volumes: EMD-45294
Expression system: Homo sapiens