Function and Biology

Human TOP3B-TDRD3 core complex in RNA rejoining state

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 5.6.2.1: DNA topoisomerase

Reaction catalysed:
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining
Systematic name:
DNA topoisomerase
Alternative Name(s):
  • DNA topoisomerase I
  • Nicking-closing enzyme
  • Omega-protein
  • Relaxing enzyme
  • Swivelase
  • Type I DNA topoisomerase
  • Untwisting enzyme

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF08585
Domain description: RMI1, N-terminal OB-fold domain
Occurring in:
  1. Tudor domain-containing protein 3

PF01131
Domain description: DNA topoisomerase
Occurring in:
  1. DNA topoisomerase 3-beta-1

PF01751
Domain description: Toprim domain
Occurring in:
  1. DNA topoisomerase 3-beta-1