› 9cip

Electron crystallography
2.5Å resolution

MicroED structure of the C11 cysteine protease clostripain

Released:
DOI: 10.2210/pdb9cip/pdb
PDB entry 9cip coloured by chain, front view.
PDB entry 9cip coloured by chain, side view.
PDB entry 9cip coloured by chain, top view.
Source organism: Hathewaya histolytica
Primary publication:
MicroED structure of the C11 cysteine protease clostripain.
Ruma YN, Bu G, Hattne J, Gonen T
J Struct Biol X 10 100107 (2024)
PMID: 39100863
Related structures: EMD-45623

Function and Biology Details

Reaction catalysed: 
Preferential cleavage: Arg-|-, including Arg-|-Pro, but not Lys-.
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-272504 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Clostripain Chains: A, B
Molecule details ›
Chains: A, B
Length: 526 amino acids
Theoretical weight: 59.81 KDa
Source organism: Hathewaya histolytica
UniProt:
  • Canonical: P09870 (Residues: 1-526; Coverage: 100%)
Gene name: cloSI
Sequence domains: Clostripain family

Ligands and Environments

1 bound ligand:
Ligand NA 7 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.5Å
Relevant EMDB volumes: EMD-45623

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