› 9ck3

Electron Microscopy
2.04Å resolution

Cryo-EM structure of in-vitro alpha-synuclein fibril

Released:
DOI: 10.2210/pdb9ck3/pdb
PDB entry 9ck3 coloured by chain, front view.
PDB entry 9ck3 coloured by chain, side view.
PDB entry 9ck3 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Sanchez JC, Borcik CG, Tonelli M, Sibert B, Rienstra CM, Wright ER
Related structures: EMD-45639

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153504 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-synuclein Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 140 amino acids
Theoretical weight: 14.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P37840 (Residues: 1-140; Coverage: 100%)
Gene names: NACP, PARK1, SNCA
Sequence domains: Synuclein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.04Å
Relevant EMDB volumes: EMD-45639
Expression system: Escherichia coli BL21(DE3)

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