9cx9

Electron Microscopy
3.34Å resolution

Structure of SH3 domain of Src in complex with beta-arrestin 1

Released:

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
PDBe Complex ID:
PDB-CPX-281429 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Antibody fragment Fab30, heavy chain Chain: H
Molecule details ›
Chain: H
Length: 237 amino acids
Theoretical weight: 25.51 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Antibody fragment Fab30, light chain Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.44 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
Vasopressin V2 receptor Chain: V
Beta-arrestin-1 Chain: A
Proto-oncogene tyrosine-protein kinase Src Chain: B

Ligands and Environments

No bound ligands
2 modified residues:

Experiments and Validation Details

Entry percentile scores
Resolution: 3.34Å
Relevant EMDB volumes: EMD-45982
Expression systems:
  • Escherichia coli
  • Not provided
  • Escherichia coli 'BL21-Gold(DE3)pLysS AG'