› 9d3a

Electron Microscopy
3.78Å resolution

Nonactive state of Gly-,Glu- bound GluN1a-2B-2D NMDAR (Low-res)

Released:
DOI: 10.2210/pdb9d3a/pdb
PDB entry 9d3a coloured by chain, front view.
PDB entry 9d3a coloured by chain, side view.
PDB entry 9d3a coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis for channel gating and blockade in tri-heteromeric GluN1-2B-2D NMDA receptor.
Kang H, Epstein M, Banke TG, Perszyk R, Simorowski N, Paladugu S, Liotta DC, Traynelis SF, Furukawa H
Neuron (2025)
PMID: 39954679
Related structures: EMD-46529

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-287916 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Glutamate receptor ionotropic, NMDA 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 825 amino acids
Theoretical weight: 92.69 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Glutamate receptor ionotropic, NMDA 2B Chain: B
Molecule details ›
Chain: B
Length: 884 amino acids
Theoretical weight: 98.62 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
Glutamate receptor ionotropic, NMDA 2D Chain: D

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand GLY 2 x GLY
Ligand NAG 4 x NAG
Ligand GLU 2 x GLU
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.78Å
Relevant EMDB volumes: EMD-46529
Expression system: Spodoptera frugiperda

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