9dlg

Electron Microscopy
5.6Å resolution

CryoEM structure of the TIR domain from human TRAM

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
PDBe Complex ID:
PDB-CPX-285019 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TIR domain-containing adapter molecule 2 Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 156 amino acids
Theoretical weight: 18.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86XR7 (Residues: 76-231; Coverage: 66%)
Gene names: TICAM2, TIRAP3, TIRP, TRAM
Sequence domains: TIR domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 5.6Å
Relevant EMDB volumes: EMD-46977
Expression system: Escherichia coli