9dof

Electron Microscopy
4.24Å resolution

Octahedral small virus-like particles of dengue virus type 2 (local reconstruction)

Released:
Source organism: dengue virus type 2
Related structures: EMD-47082

Function and Biology Details

Reactions catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective hydrolysis of -Xaa-Xaa-|-Yaa- bonds in which each of the Xaa can be either Arg or Lys and Yaa can be either Ser or Ala.
NTP + H(2)O = NDP + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-284229 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Envelope protein E Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 495 amino acids
Theoretical weight: 54.36 KDa
Source organism: dengue virus type 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P14340 (Residues: 281-775; Coverage: 15%)
Sequence domains:
Protein prM Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 166 amino acids
Theoretical weight: 18.85 KDa
Source organism: dengue virus type 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P14340 (Residues: 115-280; Coverage: 5%)
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.24Å
Relevant EMDB volumes: EMD-47082
Expression system: Homo sapiens