› 9e1h

Electron Microscopy
3.26Å resolution

Structure of RyR1 in the primed state in the presence of oxopyricid

Released:
DOI: 10.2210/pdb9e1h/pdb
PDB entry 9e1h coloured by chain, front view.
PDB entry 9e1h coloured by chain, side view.
PDB entry 9e1h coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Entry authors: Miotto MC, Marks AR
Related structures: EMD-47394

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145904 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ryanodine receptor 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 5037 amino acids
Theoretical weight: 565.91 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P11716 (Residues: 1-5037; Coverage: 100%)
Gene name: RYR1
Sequence domains:
Peptidyl-prolyl cis-trans isomerase FKBP1A Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 108 amino acids
Theoretical weight: 11.97 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P62943 (Residues: 1-108; Coverage: 100%)
Gene names: FKBP1, FKBP12, FKBP1A
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase

Ligands and Environments

4 bound ligands:
Ligand ATP 4 x ATP
Ligand CA 4 x CA
Ligand ZN 4 x ZN
Ligand A1BD5 4 x A1BD5
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.26Å
Relevant EMDB volumes: EMD-47394

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