Function and Biology Details
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 35-mer (preferred)
PDBe Complex ID:
PDB-CPX-285138 (preferred)
Entry contents:
28 distinct polypeptide molecules
2 distinct DNA molecules
1 distinct RNA molecule
2 distinct DNA molecules
1 distinct RNA molecule
Macromolecules (31 distinct):
DNA-directed RNA polymerase subunit
Chain: A
DNA-directed RNA polymerase subunit beta
Chain: B
DNA-directed RNA polymerase II subunit RPB3
Chain: C
RNA polymerase Rpb4/RPC9 core domain-containing protein
Chain: D
DNA-directed RNA polymerase II subunit E
Chain: E
DNA-directed RNA polymerases I, II, and III subunit RPABC2
Chain: F
DNA-directed RNA polymerase II subunit RPB7
Chain: G
DNA-directed RNA polymerases I, II, and III subunit RPABC3
Chain: H
DNA-directed RNA polymerase II subunit RPB9
Chain: I
DNA-directed RNA polymerases I, II, and III subunit RPABC5
Chain: J
RNA polymerase II subunit J
Chain: K
RNA polymerase II subunit K
Chain: L
Transcription elongation factor SPT6
Chain: M
Molecule details ›
Chain: M
Length: 1729 amino acids
Theoretical weight: 199.6 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 1729 amino acids
Theoretical weight: 199.6 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Protein IWS1 homolog
Chain: O
Molecule details ›
Chain: O
Length: 821 amino acids
Theoretical weight: 92.24 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 821 amino acids
Theoretical weight: 92.24 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
RNA polymerase-associated protein CTR9 homolog
Chain: Q
Molecule details ›
Chain: Q
Length: 1179 amino acids
Theoretical weight: 134.51 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 1179 amino acids
Theoretical weight: 134.51 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
RNA polymerase-associated protein RTF1 homolog
Chain: R
Molecule details ›
Chain: R
Length: 713 amino acids
Theoretical weight: 80.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 713 amino acids
Theoretical weight: 80.73 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Transcription elongation factor A protein 1
Chain: S
Molecule details ›
Chain: S
Length: 304 amino acids
Theoretical weight: 34.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 304 amino acids
Theoretical weight: 34.29 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
RNA polymerase-associated protein LEO1
Chain: U
Molecule details ›
Chain: U
Length: 666 amino acids
Theoretical weight: 75.51 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 666 amino acids
Theoretical weight: 75.51 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
RNA polymerase II-associated factor 1 homolog
Chain: V
Molecule details ›
Chain: V
Length: 531 amino acids
Theoretical weight: 60.05 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 531 amino acids
Theoretical weight: 60.05 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
WDR61
Chain: W
Molecule details ›
Chain: W
Length: 305 amino acids
Theoretical weight: 33.62 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 305 amino acids
Theoretical weight: 33.62 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Parafibromin
Chain: X
Molecule details ›
Chain: X
Length: 531 amino acids
Theoretical weight: 60.67 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 531 amino acids
Theoretical weight: 60.67 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Transcription elongation factor SPT4
Chain: Y
Molecule details ›
Chain: Y
Length: 121 amino acids
Theoretical weight: 13.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 121 amino acids
Theoretical weight: 13.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Transcription elongation factor SPT5
Chain: Z
Molecule details ›
Chain: Z
Length: 1087 amino acids
Theoretical weight: 121.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Length: 1087 amino acids
Theoretical weight: 121.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Histone H3
Chains: a, e
Molecule details ›
Chains: a, e
Length: 136 amino acids
Theoretical weight: 15.44 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Length: 136 amino acids
Theoretical weight: 15.44 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone H4
Chains: b, f
Molecule details ›
Chains: b, f
Length: 103 amino acids
Theoretical weight: 11.39 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Length: 103 amino acids
Theoretical weight: 11.39 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone H2A type 1
Chains: c, g
Molecule details ›
Chains: c, g
Length: 130 amino acids
Theoretical weight: 14.11 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Length: 130 amino acids
Theoretical weight: 14.11 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone H2B 1.1
Chains: d, h
Molecule details ›
Chains: d, h
Length: 123 amino acids
Theoretical weight: 13.66 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Length: 123 amino acids
Theoretical weight: 13.66 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone-lysine N-methyltransferase SETD2
Chain: l
Molecule details ›
Chain: l
Length: 1133 amino acids
Theoretical weight: 127.89 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Length: 1133 amino acids
Theoretical weight: 127.89 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Non-template
Chain: N
Molecule details ›
Chain: N
Length: 198 nucleotides
Theoretical weight: 60.97 KDa
Source organism: synthetic construct
Expression system: Not provided
Length: 198 nucleotides
Theoretical weight: 60.97 KDa
Source organism: synthetic construct
Expression system: Not provided
Template DNA
Chain: T
Molecule details ›
Chain: T
Length: 198 nucleotides
Theoretical weight: 61.29 KDa
Source organism: synthetic construct
Expression system: Not provided
Length: 198 nucleotides
Theoretical weight: 61.29 KDa
Source organism: synthetic construct
Expression system: Not provided
RNA
Chain: P
Molecule details ›
Chain: P
Length: 13 nucleotides
Theoretical weight: 4.13 KDa
Source organism: synthetic construct
Expression system: Not provided
Length: 13 nucleotides
Theoretical weight: 4.13 KDa
Source organism: synthetic construct
Expression system: Not provided