› 9eme

Electron Microscopy
2.92Å resolution

AL amyloid fibril from the FOR103 light chain

Released:
DOI: 10.2210/pdb9eme/pdb
PDB entry 9eme coloured by chain, front view.
PDB entry 9eme coloured by chain, side view.
PDB entry 9eme coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis.
Karimi-Farsijani S, Pfeiffer PB, Banerjee S, Baur J, Kuhn L, Kupfer N, Hegenbart U, Schönland SO, Wiese S, Haupt C, Schmidt M, Fändrich M
Nat Commun 15 5121 (2024)
PMID: 38879609
Related structures: EMD-19818

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-246487 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
lambda 3 immunoglobulin light chain fragment, residues 2-116 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 115 amino acids
Theoretical weight: 12.2 KDa
Source organism: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.92Å
Relevant EMDB volumes: EMD-19818

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