› 9ex2

X-ray diffraction
1.17Å resolution

X-ray structure of a polyoxidovanadate/lysozyme adduct obtained when the protein is treated with [VIVO(acac)2] in 1.1 M NaCl, 0.1 M sodium acetate at pH 4.0 (Structure C)

Released:
DOI: 10.2210/pdb9ex2/pdb
PDB entry 9ex2 coloured by chain, front view.
PDB entry 9ex2 coloured by chain, side view.
PDB entry 9ex2 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Non-Covalent and Covalent Binding of New Mixed-Valence Cage-like Polyoxidovanadate Clusters to Lysozyme.
Tito G, Ferraro G, Pisanu F, Garribba E, Merlino A
Angew Chem Int Ed Engl e202406669 (2024)
PMID: 38842919

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysozyme C Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.33 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P00698 (Residues: 19-147; Coverage: 100%)
Gene name: LYZ
Sequence domains: C-type lysozyme/alpha-lactalbumin family

Ligands and Environments

4 bound ligands:
Ligand NA 1 x NA
Ligand VO4 3 x VO4
Ligand A1H8D 2 x A1H8D
Ligand CL 4 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 11.2C
Spacegroup: P43212
Unit cell:
a: 78.33Å b: 78.33Å c: 37.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.157 0.156 0.189

Quick links