9f32

X-ray diffraction
2.1Å resolution

Crystal structure of ULK1 with a covalent compound GCL 99

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-130938 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase ULK1 Chain: A
Molecule details ›
Chain: A
Length: 285 amino acids
Theoretical weight: 32.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75385 (Residues: 1-283; Coverage: 27%)
Gene names: KIAA0722, ULK1
Sequence domains: Protein kinase domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 43.921Å b: 56.946Å c: 115.825Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.221 0.254
Expression system: Escherichia coli BL21(DE3)