› 9f83

X-ray diffraction
1.7Å resolution

SARS-CoV-2 Nucleocapsid N-terminal domain (NTD) mutant D63G

Released:
DOI: 10.2210/pdb9f83/pdb
PDB entry 9f83 coloured by chain, front view.
PDB entry 9f83 coloured by chain, side view.
PDB entry 9f83 coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Primary publication:
A core network in the SARS-CoV-2 nucleocapsid NTD mediates structural integrity and selective RNA-binding.
Dhamotharan K, Korn SM, Wacker A, Becker MA, Günther S, Schwalbe H, Schlundt A
Nat Commun 15 10656 (2024)
PMID: 39653699

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144998 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 136 amino acids
Theoretical weight: 14.84 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DTC9 (Residues: 41-174; Coverage: 32%)
Gene name: N
Sequence domains: Coronavirus nucleocapsid

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup: P21
Unit cell:
a: 59.013Å b: 55.665Å c: 84.895Å
α: 90° β: 95.148° γ: 90°
R-values:
R R work R free
0.232 0.229 0.28
Expression system: Escherichia coli BL21(DE3)

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