› › Function and Biology

SWR1 lacking Swc5 subunit in complex with hexasome

Source organism: Saccharomyces cerevisiae S288C
Biochemical function: protein binding
Biological process: chromatin organization
Cellular component: nucleus

Quick links

EC 3.6.4.12: DNA helicase

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (DNA helix unwinding)
Alternative Name(s):
  • 3' to 5' DNA helicase
  • 3'-5' DNA helicase
  • 3'-5' PfDH
  • 5' to 3' DNA helicase
  • AvDH1
  • BACH1 helicase
  • BLM protein
  • BRCA1-associated C-terminal helicase
  • BcMCM
  • CeWRN-1
  • DNA helicase 120
  • DNA helicase A
  • DNA helicase E
  • DNA helicase II
  • DNA helicase III
  • DNA helicase RECQL5'
  • DNA helicase VI
  • Dbp9p
  • DmRECQ5
  • DnaB
  • DnaB helicase E1
  • HHcsA
  • HPif1
  • Hel E
  • Helicase DnaB
  • Helicase HDH IV
  • Helicase domain of bacteriophage T7 gene 4 protein helicase
  • Hmi1p
  • MCM helicase
  • MCM protein
  • MER3 helicase
  • MER3 protein
  • MPH1
  • PDH120
  • PIF1
  • PcrA
  • PcrA helicase
  • PfDH A
  • Pfh1p
  • UvrD

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF17856
Domain description: TIP49 AAA-lid domain
Occurring in:
  1. RuvB-like protein 1
  2. RuvB-like protein 2
The deposited structure of PDB entry 9fbw contains 3 copies of Pfam domain PF17856 (TIP49 AAA-lid domain) in RuvB-like protein 1. Showing 1 copy in chain P [auth X].
The deposited structure of PDB entry 9fbw contains 3 copies of Pfam domain PF17856 (TIP49 AAA-lid domain) in RuvB-like protein 2. Showing 1 copy in chain M [auth U].

PF06068
Domain description: TIP49 P-loop domain
Occurring in:
  1. RuvB-like protein 1
  2. RuvB-like protein 2
The deposited structure of PDB entry 9fbw contains 3 copies of Pfam domain PF06068 (TIP49 P-loop domain) in RuvB-like protein 1. Showing 1 copy in chain P [auth X].
The deposited structure of PDB entry 9fbw contains 3 copies of Pfam domain PF06068 (TIP49 P-loop domain) in RuvB-like protein 2. Showing 1 copy in chain M [auth U].

PF00125
Domain description: Core histone H2A/H2B/H3/H4
Occurring in:
  1. Histone H3
  2. Histone H2A.1
  3. Histone H2B.1
The deposited structure of PDB entry 9fbw contains 2 copies of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H3. Showing 1 copy in chain B.
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2A.1. Showing 1 copy in chain E.
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2B.1. Showing 1 copy in chain F [auth G].

PF15511
Domain description: Centromere kinetochore component CENP-T histone fold
Occurring in:
  1. Histone H4
The deposited structure of PDB entry 9fbw contains 2 copies of Pfam domain PF15511 (Centromere kinetochore component CENP-T histone fold) in Histone H4. Showing 1 copy in chain C.

PF08265
Domain description: YL1 nuclear protein C-terminal domain
Occurring in:
  1. Vacuolar protein sorting-associated protein 72
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF08265 (YL1 nuclear protein C-terminal domain) in Vacuolar protein sorting-associated protein 72. Showing 1 copy in chain R [auth Z] (this domain is out of the observed residue ranges!).

PF05764
Domain description: YL1 nuclear protein
Occurring in:
  1. Vacuolar protein sorting-associated protein 72
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF05764 (YL1 nuclear protein) in Vacuolar protein sorting-associated protein 72. Showing 1 copy in chain R [auth Z].

PF00022
Domain description: Actin
Occurring in:
  1. Actin-like protein ARP6
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF00022 (Actin) in Actin-like protein ARP6. Showing 1 copy in chain J [auth R].

PF00271
Domain description: Helicase conserved C-terminal domain
Occurring in:
  1. Helicase SWR1
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF00271 (Helicase conserved C-terminal domain) in Helicase SWR1. Showing 1 copy in chain I [auth M].

PF00176
Domain description: SNF2-related domain
Occurring in:
  1. Helicase SWR1
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF00176 (SNF2-related domain) in Helicase SWR1. Showing 1 copy in chain I [auth M].

PF07529
Domain description: HSA domain
Occurring in:
  1. Helicase SWR1
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF07529 (HSA domain) in Helicase SWR1. Showing 1 copy in chain I [auth M] (this domain is out of the observed residue ranges!).

PF16211
Domain description: C-terminus of histone H2A
Occurring in:
  1. Histone H2A.1
The deposited structure of PDB entry 9fbw contains 1 copy of Pfam domain PF16211 (C-terminus of histone H2A) in Histone H2A.1. Showing 1 copy in chain E.

Quick links