› 9go9

Electron Microscopy
2.7Å resolution

Prepore state of alpha-Latrotoxin

Released:
DOI: 10.2210/pdb9go9/pdb
PDB entry 9go9 coloured by chain, front view.
PDB entry 9go9 coloured by chain, side view.
PDB entry 9go9 coloured by chain, top view.
Source organism: Latrodectus tredecimguttatus
Primary publication:
Structural basis of α-latrotoxin transition to a cation-selective pore.
Klink BU, Alavizargar A, Kalyankumar KS, Chen M, Heuer A, Gatsogiannis C
Nat Commun 15 8551 (2024)
PMID: 39362850
Related structures: EMD-51494

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-276178 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-latrotoxin-Lt1a Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1401 amino acids
Theoretical weight: 157.04 KDa
Source organism: Latrodectus tredecimguttatus
UniProt:
  • Canonical: P23631 (Residues: 1-1401; Coverage: 100%)
Sequence domains: Ankyrin repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.7Å
Relevant EMDB volumes: EMD-51494

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