› 9gob

Electron Microscopy
3.2Å resolution

Structure of the F-tractin-F-actin complex

Released:
DOI: 10.2210/pdb9gob/pdb
PDB entry 9gob coloured by chain, front view.
PDB entry 9gob coloured by chain, side view.
PDB entry 9gob coloured by chain, top view.
Source organisms:
Primary publication:
Structure of the F-tractin-F-actin complex.
Shatskiy D, Sivan A, Wedlich-Söldner R, Belyy A
J Cell Biol 224 (2025)
PMID: 39928047
Related structures: EMD-51496

Function and Biology Details

Reaction catalysed: 
ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-286568 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Actin, alpha skeletal muscle Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 374 amino acids
Theoretical weight: 41.76 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 4-377; Coverage: 99%)
Gene names: ACTA, ACTA1
Sequence domains: Actin
Inositol-trisphosphate 3-kinase A Chain: F
Molecule details ›
Chain: F
Length: 43 amino acids
Theoretical weight: 4.34 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P17105 (Residues: 10-52; Coverage: 9%)
Gene name: Itpka

Ligands and Environments

2 bound ligands:
Ligand ADP 5 x ADP
Ligand MG 5 x MG
1 modified residue:
Ligand HIC 5 x HIC

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.2Å
Relevant EMDB volumes: EMD-51496
Expression system: Not provided

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