Function and Biology Details
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero 31-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-283135 (preferred)
Entry contents:
26 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct RNA molecules
2 distinct DNA molecules
2 distinct RNA molecules
Macromolecules (30 distinct):
Small ribosomal subunit protein bS1
Chain: B
Molecule details ›
Chain: B
Length: 557 amino acids
Theoretical weight: 61.24 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: S1 RNA binding domain
Length: 557 amino acids
Theoretical weight: 61.24 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0AG67 (Residues: 1-557; Coverage: 100%)
Sequence domains: S1 RNA binding domain
Small ribosomal subunit protein uS2
Chain: C
Molecule details ›
Chain: C
Length: 241 amino acids
Theoretical weight: 26.78 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S2
Length: 241 amino acids
Theoretical weight: 26.78 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7V0 (Residues: 1-241; Coverage: 100%)
Sequence domains: Ribosomal protein S2
Small ribosomal subunit protein uS3
Chain: D
Molecule details ›
Chain: D
Length: 233 amino acids
Theoretical weight: 26.03 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains:
Length: 233 amino acids
Theoretical weight: 26.03 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7V3 (Residues: 1-233; Coverage: 100%)
Sequence domains:
Small ribosomal subunit protein uS4
Chain: E
Molecule details ›
Small ribosomal subunit protein uS5
Chain: F
Molecule details ›
Small ribosomal subunit protein bS6
Chain: G
Molecule details ›
Chain: G
Length: 131 amino acids
Theoretical weight: 15.2 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S6
Length: 131 amino acids
Theoretical weight: 15.2 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P02358 (Residues: 1-131; Coverage: 97%)
Sequence domains: Ribosomal protein S6
Small ribosomal subunit protein uS7
Chain: H
Molecule details ›
Chain: H
Length: 156 amino acids
Theoretical weight: 17.64 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S7p/S5e
Length: 156 amino acids
Theoretical weight: 17.64 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P02359 (Residues: 1-156; Coverage: 87%)
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein uS8
Chain: I
Molecule details ›
Chain: I
Length: 130 amino acids
Theoretical weight: 14.15 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S8
Length: 130 amino acids
Theoretical weight: 14.15 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7W7 (Residues: 1-130; Coverage: 100%)
Sequence domains: Ribosomal protein S8
Small ribosomal subunit protein uS9
Chain: J
Molecule details ›
Chain: J
Length: 130 amino acids
Theoretical weight: 14.89 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S9/S16
Length: 130 amino acids
Theoretical weight: 14.89 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7X3 (Residues: 1-130; Coverage: 100%)
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein uS10
Chain: K
Molecule details ›
Chain: K
Length: 103 amino acids
Theoretical weight: 11.76 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S10p/S20e
Length: 103 amino acids
Theoretical weight: 11.76 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7R5 (Residues: 1-103; Coverage: 100%)
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein uS11
Chain: L
Molecule details ›
Chain: L
Length: 129 amino acids
Theoretical weight: 13.87 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S11
Length: 129 amino acids
Theoretical weight: 13.87 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7R9 (Residues: 1-129; Coverage: 100%)
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS12
Chain: M
Molecule details ›
Chain: M
Length: 124 amino acids
Theoretical weight: 13.81 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S12/S23
Length: 124 amino acids
Theoretical weight: 13.81 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7S3 (Residues: 1-124; Coverage: 100%)
Sequence domains: Ribosomal protein S12/S23
Small ribosomal subunit protein uS13
Chain: N
Molecule details ›
Chain: N
Length: 118 amino acids
Theoretical weight: 13.13 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S13/S18
Length: 118 amino acids
Theoretical weight: 13.13 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7S9 (Residues: 1-118; Coverage: 100%)
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein uS14
Chain: O
Molecule details ›
Chain: O
Length: 101 amino acids
Theoretical weight: 11.61 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S14p/S29e
Length: 101 amino acids
Theoretical weight: 11.61 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0AG59 (Residues: 1-101; Coverage: 100%)
Sequence domains: Ribosomal protein S14p/S29e
Small ribosomal subunit protein uS15
Chain: P
Molecule details ›
Chain: P
Length: 89 amino acids
Theoretical weight: 10.29 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S15
Length: 89 amino acids
Theoretical weight: 10.29 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0ADZ4 (Residues: 1-89; Coverage: 100%)
Sequence domains: Ribosomal protein S15
Small ribosomal subunit protein bS16
Chain: Q
Molecule details ›
Chain: Q
Length: 82 amino acids
Theoretical weight: 9.21 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S16
Length: 82 amino acids
Theoretical weight: 9.21 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7T3 (Residues: 1-82; Coverage: 100%)
Sequence domains: Ribosomal protein S16
Small ribosomal subunit protein uS17
Chain: R
Molecule details ›
Chain: R
Length: 84 amino acids
Theoretical weight: 9.72 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S17
Length: 84 amino acids
Theoretical weight: 9.72 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0AG63 (Residues: 1-84; Coverage: 100%)
Sequence domains: Ribosomal protein S17
Small ribosomal subunit protein bS18
Chain: S
Molecule details ›
Chain: S
Length: 75 amino acids
Theoretical weight: 9.01 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S18
Length: 75 amino acids
Theoretical weight: 9.01 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7T7 (Residues: 1-75; Coverage: 100%)
Sequence domains: Ribosomal protein S18
Small ribosomal subunit protein uS19
Chain: T
Molecule details ›
Chain: T
Length: 92 amino acids
Theoretical weight: 10.46 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S19
Length: 92 amino acids
Theoretical weight: 10.46 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7U3 (Residues: 1-92; Coverage: 100%)
Sequence domains: Ribosomal protein S19
Small ribosomal subunit protein bS20
Chain: U
Molecule details ›
Chain: U
Length: 87 amino acids
Theoretical weight: 9.71 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S20
Length: 87 amino acids
Theoretical weight: 9.71 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A7U7 (Residues: 1-87; Coverage: 100%)
Sequence domains: Ribosomal protein S20
Small ribosomal subunit protein bS21
Chain: V
Molecule details ›
Chain: V
Length: 71 amino acids
Theoretical weight: 8.52 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: Ribosomal protein S21
Length: 71 amino acids
Theoretical weight: 8.52 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P68679 (Residues: 1-71; Coverage: 100%)
Sequence domains: Ribosomal protein S21
DNA-directed RNA polymerase subunit alpha
Chains: 1, 2
Molecule details ›
DNA-directed RNA polymerase subunit beta
Chain: 3
Molecule details ›
DNA-directed RNA polymerase subunit beta'
Chain: 4
Molecule details ›
DNA-directed RNA polymerase subunit omega
Chain: 5
Molecule details ›
Chain: 5
Length: 91 amino acids
Theoretical weight: 10.25 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains: RNA polymerase Rpb6
Length: 91 amino acids
Theoretical weight: 10.25 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0A800 (Residues: 1-91; Coverage: 100%)
Sequence domains: RNA polymerase Rpb6
Transcription termination/antitermination protein NusG
Chain: Z
Molecule details ›
Chain: Z
Length: 180 amino acids
Theoretical weight: 20.43 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
Sequence domains:
Length: 180 amino acids
Theoretical weight: 20.43 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
UniProt:
- Canonical: P0AFG0 (Residues: 1-180; Coverage: 99%)
Sequence domains:
Non-Template DNA strand
Chain: 6
Molecule details ›
Chain: 6
Length: 38 nucleotides
Theoretical weight: 11.76 KDa
Length: 38 nucleotides
Theoretical weight: 11.76 KDa
Template DNA strand
Chain: 7
Molecule details ›
Chain: 7
Length: 39 nucleotides
Theoretical weight: 11.89 KDa
Length: 39 nucleotides
Theoretical weight: 11.89 KDa
16S ribosomal RNA
Chain: A
Molecule details ›
Chain: A
Length: 1542 nucleotides
Theoretical weight: 499.78 KDa
Length: 1542 nucleotides
Theoretical weight: 499.78 KDa
Messenger RNA
Chain: X
Molecule details ›
Chain: X
Length: 53 nucleotides
Theoretical weight: 17.06 KDa
Length: 53 nucleotides
Theoretical weight: 17.06 KDa