› 9gxg

Electron Microscopy
1.92Å resolution

Structure of the SARS-CoV spike glycoprotein in complex with a biparatopic Bicycle molecule

Released:
DOI: 10.2210/pdb9gxg/pdb
PDB entry 9gxg coloured by chain, front view.
PDB entry 9gxg coloured by chain, side view.
PDB entry 9gxg coloured by chain, top view.
Source organisms:
Entry authors: Drulyte I, Pellegrino S, Harman M, Bezerra GA
Related structures: EMD-51660

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-290958 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1133 amino acids
Theoretical weight: 125.52 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 14-1146; Coverage: 90%)
Gene names: 2, S
Sequence domains:
Biparatopic bicycle molecule (14mer) Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 15 amino acids
Theoretical weight: 1.46 KDa
Source organism: synthetic construct
Expression system: Not provided
Biparatopic bicycle molecule (15mer) Chains: G, H, I

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
4 bound ligands:
Ligand NAG 25 x NAG
Ligand STE 3 x STE
Ligand R06 3 x R06
Ligand KZ0 3 x KZ0
2 modified residues:
Ligand 4J5 3 x 4J5
Ligand DAL 3 x DAL

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 1.92Å
Relevant EMDB volumes: EMD-51660
Expression systems:
  • Homo sapiens
  • Not provided

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