9ij2

Electron Microscopy
3.9Å resolution

Cryo-EM Structure of MILI-piRNA-target (22-nt, comma)

Released:
Source organisms:
Related structures: EMD-60613

Function and Biology Details

Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-285022 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
Macromolecules (3 distinct):
Piwi-like protein 2 Chain: A
Molecule details ›
Chain: A
Length: 971 amino acids
Theoretical weight: 109.64 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8CDG1 (Residues: 1-971; Coverage: 100%)
Gene names: Mili, Piwil2
Sequence domains:
RNA (5'-R(P*UP*UP*AP*CP*CP*AP*UP*CP*AP*AP*CP*AP*UP*GP*GP*AP*AP*AP*CP*UP*UP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 22 nucleotides
Theoretical weight: 6.99 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
RNA (5'-R(P*CP*AP*AP*GP*UP*UP*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*A)-3') Chain: C

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-60613
Expression system: Homo sapiens