9j5x

Electron Microscopy
3.44Å resolution

Cryo-EM Structure of URAT1 in Complex with Lingolinurad

Released:
Source organism: Rattus norvegicus
Entry authors: Fan J, Lei X
Related structures: EMD-61156

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-286673 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Solute carrier family 22 member 12 Chain: A
Molecule details ›
Chain: A
Length: 553 amino acids
Theoretical weight: 60.23 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q3ZAV1 (Residues: 1-553; Coverage: 100%)
Gene names: Slc22a12, Urat1
Sequence domains: Sugar (and other) transporter

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.44Å
Relevant EMDB volumes: EMD-61156
Expression system: Homo sapiens