› 9jnu

Electron Microscopy
2.5Å resolution

Structure of isw1-nucleosome complex in ADP state

Released:
DOI: 10.2210/pdb9jnu/pdb
PDB entry 9jnu coloured by chain, front view.
PDB entry 9jnu coloured by chain, side view.
PDB entry 9jnu coloured by chain, top view.
Source organisms:
Primary publication:
Structural insights into chromatin remodeling by ISWI during active ATP hydrolysis.
Sia Y, Pan H, Chen K, Chen Z
Science eadu5654 (2025)
PMID: 40179160
Related structures: EMD-61627

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero undecamer (preferred)
PDBe Complex ID:
PDB-CPX-292568 (preferred)
Entry contents:
5 distinct polypeptide molecules
2 distinct DNA molecules
Macromolecules (7 distinct):
Histone H3 Chains: A, E
Molecule details ›
Chains: A, E
Length: 135 amino acids
Theoretical weight: 15.3 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone H4 Chains: B, F
Molecule details ›
Chains: B, F
Length: 102 amino acids
Theoretical weight: 11.26 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
Histone H2A Chains: C, G
Histone H2B Chains: D, H
ISWI chromatin-remodeling complex ATPase ISW1 Chain: K
DNA (146-MER) Chain: I
DNA (146-MER) Chain: J

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.5Å
Relevant EMDB volumes: EMD-61627
Expression system: Escherichia coli

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