› 9jvh

Electron Microscopy
2.76Å resolution

Cryo-EM structure of the mmGPR4-Gs receptor in pH6.2

Released:
DOI: 10.2210/pdb9jvh/pdb
PDB entry 9jvh coloured by chain, front view.
PDB entry 9jvh coloured by chain, side view.
PDB entry 9jvh coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Evolutionary study and structural basis of proton sensing by Mus GPR4 and Xenopus GPR4.
Wen X, Shang P, Chen H, Guo L, Rong N, Jiang X, Li X, Liu J, Yang G, Zhang J, Zhu K, Meng Q, He X, Wang Z, Liu Z, Cheng H, Zheng Y, Zhang B, Pang J, Liu Z, Xiao P, Chen Y, Liu L, Luo F, Yu X, Yi F, Zhang P, Yang F, Deng C, Sun JP
Cell 188 653-670.e24 (2025)
PMID: 39753131
Related structures: EMD-61839, EMD-61838

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-286695 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
G-protein coupled receptor 4 Chain: R
Molecule details ›
Chain: R
Length: 365 amino acids
Theoretical weight: 41.15 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8BUD0 (Residues: 1-365; Coverage: 100%)
Gene name: Gpr4
Sequence domains: 7 transmembrane receptor (rhodopsin family)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.76Å
Relevant EMDB volumes: EMD-61839, EMD-61838
Expression system: Spodoptera frugiperda

Quick links