All structure family : 5' to 3' exonuclease, C-terminal subdomain
 
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Entries released this week  (1)
revised
(1)
 
Entry Information
Entry status  (1)
REL
(1224)
 
Experimental methods  (3)
X-ray diffraction
(1205)
Solution NMR
(14)
Electron Microscopy
(5)
 
Authors  (1097)
Wilson SH
(225)
Beard WA
(153)
Pedersen LC
(115)
Egli M
(108)
Batra VK
(104)
Pelletier H
(103)
Sawaya MR
(103)
Yang W
(93)
Beese LS
(91)
Shock DD
(78)
Guengerich FP
(77)
Kunkel TA
(77)
Bebenek K
(70)
Kraut J
(59)
Lee S
(59)
Freudenthal BD
(58)
McKenna CE
(54)
Koag MC
(52)
Wolfle W
(50)
Goodman MF
(49)
Suo Z
(49)
Kashemirov BA
(47)
Nair DT
(44)
Hellinga HW
(42)
Moon AF
(42)
Gao Y
(40)
Patra A
(40)
Diederichs K
(39)
Marx A
(39)
Welte W
(39)
Krahn JM
(38)
Garcia-Diaz M
(37)
Zhao Y
(37)
Ling H
(35)
Delarue M
(34)
Tsai MD
(34)
Aggarwal AK
(33)
Hua YJ
(32)
Liu XX
(31)
Vyas R
(31)
Wu WJ
(31)
Oertell K
(30)
Prakash L
(30)
Prakash S
(30)
Eoff RL
(29)
Reed AJ
(29)
Gouge J
(28)
Johnson RE
(28)
Rechkoblit O
(28)
Koag M-C
(27)
Kottur J
(27)
Rizzo CJ
(27)
Rosario S
(27)
Su Y
(27)
Wang W
(27)
Gregory MT
(26)
Beguin P
(24)
Carell T
(24)
Ko TP
(24)
Ramsden DA
(24)
Romain F
(24)
Zhang Q
(24)
Doublie S
(23)
Doublié S
(23)
Banerjee S
(22)
Irimia A
(22)
Patel DJ
(22)
Li Y
(21)
Stone MP
(21)
Biertumpfel C
(20)
Biertümpfel C
(20)
Ellenberger T
(20)
Gregory M
(20)
Hanaoka F
(20)
Johnson SJ
(20)
Pryor JM
(20)
Bessho Y
(19)
Chang YK
(19)
Choi JY
(19)
Huang YP
(19)
Kawano Y
(19)
Maestre-Reyna M
(19)
Perera L
(19)
Steitz TA
(19)
Sweasy JB
(19)
Geacintov NE
(18)
Smith MR
(18)
Angel KC
(17)
Nakamura T
(17)
Obeid S
(17)
Yamagata Y
(17)
Christov PP
(16)
Kou Y
(16)
Kozekov ID
(16)
He Y
(15)
Luo Y
(15)
Sayers JR
(15)
Schneider S
(15)
Wu EY
(15)
Wu Y
(15)
 
More...
 
Homo / hetero assembly  (2)
hetero
(1077)
homo
(147)
 
Assembly composition  (7)
DNA/protein complex
(1020)
protein structure
(147)
protein/protein complex
(33)
DNA/DNA/RNA hybrid/protein complex
(10)
DNA/RNA/protein complex
(8)
RNA/protein complex
(4)
DNA/RNA hybrid/protein complex
(2)
 
Assembly polymer count  (15)
trimer
(590)
tetramer
(414)
monomer
(125)
dimer
(49)
hexamer
(25)
octamer
(7)
heptamer
(3)
pentamer
(3)
decamer
(2)
34-mer
(1)
35-mer
(1)
36-mer
(1)
45-mer
(1)
dodecamer
(1)
undecamer
(1)
 
Resolution distribution
1.0 - 1.5
(19)
1.5 - 2
(402)
2.0 - 2.5
(431)
2.5 - 3
(263)
3.0 - 3.5
(69)
3.5 - 4
(24)
4.0 - 4.5
(1)
9.5 - 10
(1)
 
Release year distribution
1990 - 1995
(16)
1995 - 2000
(143)
2000 - 2005
(127)
2005 - 2010
(244)
2010 - 2015
(482)
2015 - 2020
(385)
 
Journal  (50)
Biochemistry
(160)
J Biol Chem
(130)
Proc Natl Acad Sci U S A
(113)
J Am Chem Soc
(112)
Nucleic Acids Res
(105)
Structure
(86)
Nature
(55)
EMBO J
(54)
Science
(54)
Cell
(50)
To be published
(50)
J Mol Biol
(38)
Nat Struct Mol Biol
(34)
Mol Cell
(20)
Nat Commun
(20)
Nat Chem Biol
(15)
Chem Res Toxicol
(12)
Angew Chem Int Ed Engl
(10)
J Med Chem
(10)
Biochem J
(8)
DNA Repair (Amst)
(8)
Chem Sci
(7)
Chembiochem
(6)
Acta Crystallogr D Biol Crystallogr
(5)
Acta Crystallogr Sect F Struct Biol Cryst Commun
(5)
PLoS Biol
(5)
PLoS One
(5)
Nat Struct Biol
(4)
Sci Rep
(4)
BMC Struct Biol
(3)
Biochim Biophys Acta
(3)
Nat Chem
(3)
Org Lett
(3)
Protein Sci
(3)
Chem Biol Drug Des
(2)
Chem Commun (Camb)
(2)
Chemistry
(2)
EMBO Rep
(2)
Elife
(2)
J Bacteriol
(2)
Mol Microbiol
(2)
Bioorg Med Chem Lett
(1)
Cell Cycle
(1)
Cell Res
(1)
Chem Biol
(1)
Genes Dev
(1)
J Struct Biol
(1)
Molecules
(1)
Nat Methods
(1)
Proteins
(1)
 
Macromolecules
Organism superkingdom  (4)
Eukaryota
(755)
Bacteria
(256)
Archaea
(171)
Viruses
(42)
 
Organism name  (43)
Homo sapiens
(664)
Saccharolobus solfataricus P2
(91)
Geobacillus stearothermophilus
(67)
Thermus aquaticus
(50)
Saccharolobus solfataricus
(43)
Escherichia coli K-12
(39)
Escherichia coli
(36)
Mus musculus
(35)
Escherichia phage T7
(28)
Rattus norvegicus
(26)
Saccharomyces cerevisiae
(20)
Geobacillus kaustophilus HTA426
(17)
Thermotoga maritima
(12)
Methanococcus voltae
(11)
Escherichia virus T5
(8)
Escherichia virus T4
(6)
Geobacillus
(6)
Pyrococcus furiosus
(6)
Saccharomyces cerevisiae S288C
(6)
Sulfolobus acidocaldarius DSM 639
(6)
Archaeoglobus fulgidus
(5)
Thermus thermophilus HB8
(5)
Geobacillus kaustophilus
(4)
Sulfolobus acidocaldarius
(4)
Bacillus subtilis
(3)
Escherichia coli O139:H28 str. E24377A
(3)
Leishmania infantum
(3)
Methanococcus maripaludis
(3)
Mycobacterium tuberculosis
(3)
Aeropyrum pernix
(2)
Escherichia coli O157:H7
(2)
Listeria monocytogenes serotype 4b str. F2365
(2)
Methanocaldococcus jannaschii
(2)
Thermus filiformis
(2)
Thermus thermophilus
(2)
Chaetomium thermophilum
(1)
Deinococcus radiodurans
(1)
Desulfurococcus amylolyticus
(1)
Methanococcus voltae PS
(1)
Mycobacterium tuberculosis H37Rv
(1)
Mycolicibacterium smegmatis MC2 155
(1)
Pyrococcus horikoshii
(1)
Yersinia pseudotuberculosis
(1)
 
Molecule name  (122)
DNA polymerase beta
(389)
5'-deoxyribose-phosphate lyase
(386)
AP lyase
(386)
5'-dRP lyase
(381)
DNA polymerase IV
(160)
Pol IV
(160)
DNA polymerase eta
(130)
RAD30 homolog A
(119)
Xeroderma pigmentosum variant type protein
(119)
DNA polymerase I
(107)
Terminal transferase
(91)
DNA-directed DNA/RNA polymerase mu
(57)
Pol Mu
(57)
DNA polymerase beta-2
(55)
DNA polymerase kappa
(55)
DNA polymerase lambda
(55)
Pol Lambda
(55)
Pol beta2
(55)
DNA polymerase I, thermostable
(50)
Taq polymerase 1
(50)
POL I
(45)
DNA polymerase iota
(40)
Eta2
(40)
RAD30 homolog B
(40)
DNA nucleotidylexotransferase
(34)
TDT
(34)
Terminal addition enzyme
(34)
Terminal deoxynucleotidyltransferase
(34)
DNA-directed DNA polymerase I
(29)
TSL polymerase IV
(27)
Translesion synthesis polymerase IV
(27)
DNA-directed RNA polymerase subunit alpha
(25)
RNA polymerase subunit alpha
(25)
RNAP subunit alpha
(25)
Transcriptase subunit alpha
(25)
DNA repair and recombination protein RadA
(22)
Dna polymerase i
(19)
DNA-directed DNA polymerase
(18)
Gene product 5
(17)
Gp5
(17)
Exonuclease 1
(15)
Exonuclease I
(15)
FEN
(15)
hExo1
(15)
hExoI
(15)
FEN-1
(14)
Flap endonuclease 1
(14)
Flap structure-specific endonuclease 1
(14)
DNA-directed RNA polymerase
(11)
Radiation-sensitive protein 30
(11)
T7 RNA polymerase
(11)
Holliday junction branch migration complex subunit RuvA
(9)
5'-3' exonuclease
(8)
Exodeoxyribonuclease
(8)
Flap endonuclease
(8)
Cyclic di-AMP synthase
(7)
DNA integrity scanning protein DisA
(7)
DNA repair protein REV1
(7)
DNase IV
(7)
Diadenylate cyclase
(7)
Flap endonuclease Xni
(7)
MF1
(7)
Maturation factor 1
(7)
Pre-mRNA-splicing helicase BRR2
(7)
Protein Snu246
(7)
c-di-AMP synthase
(7)
hFEN-1
(7)
Excinuclease ABC subunit C
(6)
Protein UvrC
(6)
RNase H
(6)
Reversionless protein 1
(6)
Ribonuclease H
(6)
UvrABC system protein C
(6)
Activating signal cointegrator 1 complex subunit 3-like 1
(5)
BRR2 homolog
(5)
DNA excision repair protein ERCC-4
(5)
DNA ligase
(5)
DNA polymerase beta family (X family)
(5)
DNA repair endonuclease XPF
(5)
DNA repair protein complementing XP-F cells
(5)
N utilization substance protein A
(5)
Polydeoxyribonucleotide synthase [NAD(+)]
(5)
Transcription termination/antitermination L factor
(5)
Transcription termination/antitermination protein NusA
(5)
U5 small nuclear ribonucleoprotein 200 kDa helicase
(5)
U5 snRNP-specific 200 kDa protein
(5)
U5-200KD
(5)
Xeroderma pigmentosum group F-complementing protein
(5)
Fanconi anemia core complex-associated protein 24
(4)
Fanconi anemia-associated protein of 24 kDa
(4)
ATP-dependent DNA helicase Hel308
(3)
ATP-dependent Holliday junction unwindase Hjm
(3)
DNA 3'-5' helicase Hel308
(3)
DNA excision repair protein ERCC-1
(3)
DNA polymerase
(3)
DNA polymerase I, large fragment
(3)
Holliday junction migration DNA helicase
(3)
ATP-dependent RNA helicase FANCM
(2)
DNA repair protein RAD51
(2)
DNA repair protein RAD51 homolog 1
(2)
 
More...
 
Molecule type  (1)
Protein
(1224)
 
Gene names  (128)
1
(11)
5
(17)
POLB
(355)
polA
(151)
dbh
(132)
RAD30
(130)
SSO2448
(125)
dpo4
(125)
POLH
(119)
RAD30A
(119)
XPV
(119)
polmu
(57)
POLM
(56)
POLL
(55)
pol1
(50)
POLI
(40)
RAD30B
(40)
Dntt
(34)
Tdt
(34)
pol
(32)
GK2730
(29)
dinB
(28)
JW0221
(27)
b0231
(27)
dinP
(27)
Polb
(26)
rpoA
(25)
radA
(22)
JW3257
(16)
b3295
(16)
pez
(16)
phs
(16)
sez
(16)
EXO1
(15)
EXOI
(15)
HEX1
(15)
JW3835
(13)
b3863
(13)
resA
(13)
BRR2
(12)
DBH1
(11)
YDR419W
(11)
Saci_0554
(10)
ruvA
(9)
D15
(8)
T5.130
(8)
T5p128
(8)
exo5
(8)
ECs3658
(7)
FEN1
(7)
RAD2
(7)
REV1
(7)
RSS1
(7)
SNU246
(7)
SYGP-ORF66
(7)
TM_0200
(7)
YER172C
(7)
Z4115
(7)
disA
(7)
fen
(7)
xni
(7)
ygdG
(7)
33.2
(6)
O6339
(6)
SSO0250
(6)
YOR346W
(6)
das
(6)
rnh
(6)
uvrC
(6)
ASCC3L1
(5)
ERCC11
(5)
ERCC4
(5)
HELIC2
(5)
JW3138
(5)
KIAA0788
(5)
SNRNP200
(5)
TM_0265
(5)
TTHA1150
(5)
XPF
(5)
b3169
(5)
ligA
(5)
nusA
(5)
C19orf40
(4)
FAAP24
(4)
JW1850
(4)
MTCY227.08
(4)
RAD51
(4)
Rv2593c
(4)
b1861
(4)
BSU01430
(3)
DPO1
(3)
ERCC1
(3)
EcE24377A_3778
(3)
JW2403
(3)
PF0677
(3)
b2411
(3)
dnaL
(3)
hel308
(3)
hjm
(3)
lig
(3)
 
More...
 
Interacting Molecules  (912)
DNA (5'-D(P*GP*TP*CP*GP*G)-3')
(131)
DNA (5'-D(P*GP*CP*CP*G)-3')
(60)
5'-D(P*GP*TP*CP*GP*G)-3'
(57)
DNA (5'-D(*CP*AP*TP*TP*AP*GP*AP*A)-3')
(55)
DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')
(50)
DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3')
(47)
DNA (5'-D(*TP*CP*TP*AP*AP*TP*G)-3')
(44)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3')
(38)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3')
(36)
DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3')
(33)
Downstream Primer Strand
(32)
Primer Strand
(32)
Template Strand
(31)
DNA (5'-D(*CP*AP*GP*AP*TP*G)-3')
(30)
DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3')
(29)
DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(28)
DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3')
(25)
5'-D(P*GP*CP*CP*G)-3'
(18)
DNA (5'-D(*CP*GP*TP*AP*T)-3')
(18)
5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'
(17)
Thioredoxin 1
(17)
5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'
(16)
DNA (5'-D(*CP*AP*GP*TP*AP*C)-3')
(16)
DNA PRIMER STRAND
(14)
DNA TEMPLATE STRAND
(14)
DNA-directed RNA polymerase subunit beta
(14)
DNA-directed RNA polymerase subunit beta'
(14)
DNA-directed RNA polymerase subunit omega
(14)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'
(13)
DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(13)
DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(13)
DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3')
(13)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3'
(12)
DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(12)
DNA (5'-D(*CP*GP*TP*A)-3')
(12)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DOC))-3')
(12)
5'-D(*AP*AP*AP*AP*AP*C)-3'
(11)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'
(11)
DNA primer strand
(11)
DTN1
(11)
DTN2
(11)
RNA polymerase sigma factor RpoD
(11)
DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3')
(10)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3')
(10)
DNA (5'-D(P*AP*GP*GP*AP*CP*CP*C)-3')
(10)
DNA
(9)
DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3')
(9)
DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3')
(9)
DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3')
(9)
DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3')
(9)
5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'
(8)
5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*C)-3'
(8)
DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3')
(8)
DNA (5'-D(*TP*CP*TP*AP*AP*TP*GP*A)-3')
(8)
10- MER PRIMER
(7)
16- MER TEMPLATE
(7)
5-MER PHOSPHORYLATED DOWNSTREAM PRIMER
(7)
DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(7)
DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3')
(7)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(2DA))-3')
(7)
DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3')
(7)
DNA Downstream Strand
(7)
DNA Primer Strand
(7)
DNA Template Strand
(7)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3'
(6)
DNA (5'-D(*AP*CP*CP*GP*TP*CP*C)-3')
(6)
DNA (5'-D(*AP*CP*TP*CP*TP*GP*CP*CP*TP*CP*AP*AP*GP*AP*CP*GP*GP*T)-3')
(6)
DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(6)
DNA (5'-D(*CP*CP*GP*AP*CP*GP*CP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(6)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(8OG))-3')
(6)
DNA (5'-D(*GP*TP*CP*GP*G)-3')
(6)
DNA primer
(6)
DNA template
(6)
DNA/RNA (5'-D(*CP*GP*TP*A)-R(P*U)-3')
(6)
Pre-mRNA-splicing factor 8
(6)
5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3'
(5)
5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3'
(5)
5'-D(*GP*CP*CP*G)-3'
(5)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'
(5)
5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*C)-3'
(5)
DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3')
(5)
DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3')
(5)
DNA (5'-D(*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(5)
DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')
(5)
DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*A)-3')
(5)
DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3')
(5)
DNA (5'-D(P*CP*AP*GP*GP*AP*GP*TP*CP*CP*TP*GP*TP*AP*GP*CP*C)-3')
(5)
DNA (5'-D(P*GP*GP*CP*TP*AP*CP*AP*GP*GP*AP*CP*TP*C)-3')
(5)
DNA template strand with 8-oxoguanine
(5)
(5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3')
(4)
(5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3')
(4)
5'-D(*CP*AP*GP*TP*AP*CP*G)-3'
(4)
5'-D(*CP*AP*TP*(6OG)P*CP*GP*AP*GP*TP*CP*AP*GP*G)-3'
(4)
5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3'
(4)
5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DDG))-3'
(4)
5'-D(*CP*TP*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*C)-3'
(4)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*A)-3'
(4)
5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*DOC)-3'
(4)
5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*A)-3'
(4)
5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3'
(4)
 
More...
 
Interacting ligands  (192)
MG : MAGNESIUM ION
(521)
NA : SODIUM ION
(479)
CA : CALCIUM ION
(229)
GOL : GLYCEROL
(162)
SO4 : SULFATE ION
(151)
MN : MANGANESE (II) ION
(144)
CL : CHLORIDE ION
(143)
DTP : 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
(96)
DCP : 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE
(81)
EDO : 1,2-ETHANEDIOL
(78)
TTP : THYMIDINE-5'-TRIPHOSPHATE
(65)
DGT : 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
(57)
PPV : PYROPHOSPHATE
(57)
GLC : alpha-D-glucopyranose
(53)
FRU : beta-D-fructofuranose
(52)
PRD_900003 : sucrose
(52)
ZN : ZINC ION
(42)
ACT : ACETATE ION
(38)
0KX : 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine
(37)
DCT : 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE
(36)
DPO : DIPHOSPHATE
(34)
EPE : 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
(34)
K : POTASSIUM ION
(29)
DUP : 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE
(28)
PO4 : PHOSPHATE ION
(21)
1FZ : 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine
(20)
XG4 : 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine
(20)
D3T : 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE
(18)
DZ4 : 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine
(16)
CTP : CYTIDINE-5'-TRIPHOSPHATE
(15)
ATP : ADENOSINE-5'-TRIPHOSPHATE
(14)
FMT : FORMIC ACID
(13)
ANP : PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
(12)
DTT : 2,3-DIHYDROXY-1,4-DITHIOBUTANE
(12)
DG3 : 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE
(11)
8DG : 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE
(10)
MES : 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
(10)
DC : 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE
(9)
MPD : (4S)-2-METHYL-2,4-PENTANEDIOL
(9)
6CF : 2'-deoxy-5'-O-[(S)-{difluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]cytidine
(8)
APC : DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
(8)
DAD : 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE
(8)
F2A : 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine
(8)
PEG : DI(HYDROXYETHYL)ETHER
(8)
ADP : ADENOSINE-5'-DIPHOSPHATE
(7)
DDS : 2',3'-dideoxyadenosine triphosphate
(7)
IMD : IMIDAZOLE
(7)
PGE : TRIETHYLENE GLYCOL
(7)
STP : 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE)
(7)
1GC : 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine
(6)
2KH : 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine
(6)
GOA : GLYCOLIC ACID
(6)
1PE : PENTAETHYLENE GLYCOL
(5)
AF : 2-AMINOFLUORENE
(5)
BAP : 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE
(5)
CO : COBALT (II) ION
(5)
NI : NICKEL (II) ION
(5)
POP : PYROPHOSPHATE 2-
(5)
SM : SAMARIUM (III) ION
(5)
UTP : URIDINE 5'-TRIPHOSPHATE
(5)
1RZ : Lamivudine Triphosphate
(4)
CR : CHROMIUM ION
(4)
GKS : 1-[2-amino-5-(formylamino)-6-oxo-1,6-dihydropyrimidin-4-yl]-2,5-anhydro-1,3-dideoxy-6-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-D-ribo-hexitol
(4)
1RY : [[(2R,5S)-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
(3)
2BA : (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide
(3)
AMP : ADENOSINE MONOPHOSPHATE
(3)
BA : BARIUM ION
(3)
CIT : CITRIC ACID
(3)
DOC : 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE
(3)
HG : MERCURY (II) ION
(3)
0OH : North-methanocarba-2'-deoxyadenosine triphosphate
(2)
0OJ : South-methanocarba-2'-deoxyadenosine triphosphate
(2)
15P : POLYETHYLENE GLYCOL (N=34)
(2)
1FO : 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
(2)
1FQ : (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid
(2)
1S0 : 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one
(2)
2PN : IMIDODIPHOSPHORIC ACID
(2)
3AT : 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE
(2)
42E : [(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl]methyl dihydrogen phosphate
(2)
8CP : 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]cytidine
(2)
ADI : 2',3'-DIDEOXYADENOSINE-5'-DIPHOSPHATE
(2)
BGL : 2-O-octyl-beta-D-glucopyranose
(2)
CAC : CACODYLATE ION
(2)
CD : CADMIUM ION
(2)
D5M : 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE
(2)
DG : 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE
(2)
DJJ : 5'-O-[(R)-{[(R)-[(S)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxycytidine
(2)
F3C : 2'-deoxy-5'-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine
(2)
FDJ : 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]thymidine
(2)
G1C : 5'-O-[(R)-{[(S)-[(S)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxyguanosine
(2)
GFH : 2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE
(2)
IOD : IODIDE ION
(2)
MRD : (4R)-2-METHYLPENTANE-2,4-DIOL
(2)
PG4 : TETRAETHYLENE GLYCOL
(2)
SAN : SULFANILAMIDE
(2)
TRS : 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
(2)
TTE : PHOSPHOMETHYL PHOSPHONIC ACID DEOXYTHYMIDYLATE ESTER
(2)
TTW : 5'-O-[hydroxy{[hydroxy(phosphonoamino)phosphoryl]oxy}phosphoryl]thymidine
(2)
XC5 : 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine
(2)
0G4 : [[[[(2R,5S)-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy -oxidanyl-phosphoryl]amino]phosphonic acid
(1)
 
More...
 
Function and Biology
EC number / name  (9)
2.7.7.7 : DNA-directed DNA polymerase
(1000)
4.2.99.18 : DNA-(apurinic or apyrimidinic site) lyase
(386)
2.7.7.6 : DNA-directed RNA polymerase
(36)
2.7.7.31 : DNA nucleotidylexotransferase
(34)
3.6.4.13 : RNA helicase
(14)
3.1.11.3 : Exodeoxyribonuclease (lambda-induced)
(8)
2.7.7.85 : Diadenylate cyclase
(7)
3.1.26.4 : Ribonuclease H
(6)
6.5.1.2 : DNA ligase (NAD(+))
(5)
 
Biological function  (71)
DNA binding
(1007)
DNA-directed DNA polymerase activity
(917)
nucleotidyltransferase activity
(759)
damaged DNA binding
(731)
DNA polymerase activity
(726)
metal ion binding
(611)
transferase activity
(605)
protein binding
(437)
enzyme binding
(369)
5'-deoxyribose-5-phosphate lyase activity
(368)
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
(368)
lyase activity
(368)
microtubule binding
(368)
DNA-(apurinic or apyrimidinic site) endonuclease activity
(355)
nucleic acid binding
(192)
magnesium ion binding
(170)
3'-5' exonuclease activity
(124)
nuclease activity
(96)
hydrolase activity
(86)
nucleotide binding
(86)
catalytic activity
(75)
exonuclease activity
(64)
ATP binding
(58)
nucleoside binding
(50)
DNA-directed RNA polymerase activity
(36)
ATP hydrolysis activity
(34)
endonuclease activity
(30)
5'-3' exonuclease activity
(29)
5'-flap endonuclease activity
(29)
hydrolase activity, acting on ester bonds
(29)
3'-5'-DNA exonuclease activity
(27)
ATP-dependent DNA damage sensor activity
(25)
ATP-dependent activity, acting on DNA
(25)
DNA exonuclease activity
(25)
5'-3' RNA polymerase activity
(24)
catalytic activity, acting on a nucleic acid
(24)
5'-3' DNA exonuclease activity
(23)
identical protein binding
(22)
flap endonuclease activity
(16)
protein dimerization activity
(14)
helicase activity
(11)
DNA helicase activity
(9)
four-way junction helicase activity
(9)
double-stranded DNA 5'-3' DNA exonuclease activity
(8)
double-stranded DNA endonuclease activity
(8)
four-way junction DNA binding
(8)
RNA-DNA hybrid ribonuclease activity
(7)
adenylate cyclase activity
(7)
catalytic activity, acting on DNA
(7)
diadenylate cyclase activity
(7)
potassium ion binding
(7)
5'-3' RNA exonuclease activity
(6)
phosphoric ester hydrolase activity
(6)
zinc ion binding
(6)
DNA ligase (NAD+) activity
(5)
RNA helicase activity
(5)
excinuclease ABC activity
(5)
double-stranded DNA binding
(4)
3'-5' DNA helicase activity
(3)
DNA strand exchange activity
(3)
chromatin binding
(3)
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
(3)
isomerase activity
(3)
single-stranded DNA binding
(3)
NAD+ binding
(2)
ligase activity
(2)
DNA endonuclease activity
(1)
DNA polymerase binding
(1)
double-stranded DNA exodeoxyribonuclease activity
(1)
manganese ion binding
(1)
single-stranded DNA helicase activity
(1)
 
Biological process  (98)
DNA repair
(1011)
DNA replication
(724)
DNA-templated DNA replication
(684)
DNA damage response
(610)
DNA metabolic process
(473)
DNA biosynthetic process
(402)
double-strand break repair via nonhomologous end joining
(371)
base-excision repair
(369)
base-excision repair, gap-filling
(369)
apoptotic process
(368)
homeostasis of number of cells
(368)
immunoglobulin heavy chain V-D-J recombination
(368)
in utero embryonic development
(368)
inflammatory response
(368)
intrinsic apoptotic signaling pathway in response to DNA damage
(368)
lymph node development
(368)
neuron apoptotic process
(368)
nucleotide-excision repair, DNA gap filling
(368)
pyrimidine dimer repair
(368)
response to ethanol
(368)
response to gamma radiation
(368)
response to hyperoxia
(368)
salivary gland morphogenesis
(368)
somatic diversification of immunoglobulins
(368)
somatic hypermutation of immunoglobulin genes
(368)
spleen development
(368)
error-prone translesion synthesis
(155)
nucleobase-containing compound metabolic process
(107)
double-strand break repair
(44)
DNA-templated transcription
(36)
SOS response
(35)
DNA recombination
(34)
DNA synthesis involved in DNA repair
(27)
error-free translesion synthesis
(27)
viral DNA genome replication
(25)
DNA replication, Okazaki fragment processing
(21)
DNA synthesis involved in DNA replication
(17)
DNA replication, removal of RNA primer
(14)
DNA-templated transcription initiation
(10)
DNA-templated viral transcription
(10)
bacterial-type flagellum assembly
(10)
bacterial-type flagellum-dependent cell motility
(10)
cell motility
(10)
cellular response to cell envelope stress
(10)
intracellular iron ion homeostasis
(10)
nitrate assimilation
(10)
regulation of DNA-templated transcription elongation
(10)
regulation of DNA-templated transcription initiation
(10)
response to heat
(10)
submerged biofilm formation
(10)
transcription antitermination
(10)
viral transcription
(10)
double-strand break repair via homologous recombination
(8)
late viral transcription
(8)
RNA splicing
(5)
interstrand cross-link repair
(5)
mRNA processing
(5)
mRNA splicing, via spliceosome
(5)
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
(5)
mitotic recombination-dependent replication fork processing
(3)
recombinational repair
(3)
response to radiation
(3)
DNA recombinase assembly
(2)
DNA strand invasion
(2)
chromosome organization involved in meiotic cell cycle
(2)
mitotic recombination
(2)
reciprocal meiotic recombination
(2)
telomere maintenance via recombination
(2)
DNA restriction-modification system
(1)
G2/M transition of mitotic cell cycle
(1)
UV protection
(1)
cellular response to alkaloid
(1)
cellular response to camptothecin
(1)
cellular response to cisplatin
(1)
cellular response to gamma radiation
(1)
cellular response to hydroxyurea
(1)
cellular response to ionizing radiation
(1)
double-strand break repair involved in meiotic recombination
(1)
heteroduplex formation
(1)
meiosis I
(1)
meiosis I cell cycle process
(1)
meiotic cell cycle
(1)
meiotic joint molecule formation
(1)
memory
(1)
mitochondrial DNA repair
(1)
nucleotide-excision repair
(1)
positive regulation of sister chromatid cohesion
(1)
regulation of DNA damage checkpoint
(1)
regulation of double-strand break repair via homologous recombination
(1)
replication fork processing
(1)
replication-born double-strand break repair via sister chromatid exchange
(1)
response to X-ray
(1)
response to glucoside
(1)
response to toxic substance
(1)
response to xenobiotic stimulus
(1)
telomere maintenance via semi-conservative replication
(1)
telomere maintenance via telomere lengthening
(1)
telomere organization
(1)
 
Biological cell component  (41)
cytoplasm
(551)
nucleus
(441)
protein-containing complex
(370)
microtubule
(368)
spindle microtubule
(368)
nucleoplasm
(359)
DNA-directed RNA polymerase complex
(24)
cytosol
(22)
membrane
(11)
cytosolic DNA-directed RNA polymerase complex
(10)
transcription elongation factor complex
(10)
Holliday junction helicase complex
(8)
Holliday junction resolvase complex
(8)
viral replication complex
(8)
Prp19 complex
(5)
U4/U6 x U5 tri-snRNP complex
(5)
U5 snRNP
(5)
spliceosomal complex
(5)
Fanconi anaemia nuclear complex
(4)
plasma membrane
(4)
chromatin
(3)
FANCM-MHF complex
(2)
chromosome
(2)
chromosome, telomeric region
(2)
condensed nuclear chromosome
(2)
intracellular membrane-bounded organelle
(2)
mitochondrial matrix
(2)
mitochondrion
(2)
nuclear chromosome
(2)
nucleolus
(2)
PML body
(1)
centrosome
(1)
condensed chromosome
(1)
cytoskeleton
(1)
lateral element
(1)
male germ cell nucleus
(1)
mitochondrial chromosome
(1)
nuclear ubiquitin ligase complex
(1)
perinuclear region of cytoplasm
(1)
presynaptic intermediate filament cytoskeleton
(1)
site of double-strand break
(1)
 
Compound cofactor class  (1)
Nicotinamide-adenine dinucleotide
(1)
 
Sequence and Structure classification
SCOP fold  (14)
SAM domain-like
(191)
DNA/RNA polymerases
(159)
Nucleotidyltransferase
(144)
Ribonuclease H-like motif
(83)
Lesion bypass DNA polymerase (Y-family), little finger domain
(66)
PIN domain-like
(16)
P-loop containing nucleoside triphosphate hydrolases
(11)
OB-fold
(7)
RuvA C-terminal domain-like
(4)
Restriction endonuclease-like
(3)
Sec63 N-terminal domain-like
(3)
ATP-grasp
(2)
DNA/RNA-binding 3-helical bundle
(2)
Immunoglobulin-like beta-sandwich
(1)
 
SCOP family  (30)
DNA polymerase beta-like
(144)
DNA polymerase beta-like, second domain
(144)
DNA polymerase beta, N-terminal domain-like
(132)
DNA polymerase I
(83)
DnaQ-like 3'-5' exonuclease
(83)
Lesion bypass DNA polymerase (Y-family), catalytic domain
(66)
Lesion bypass DNA polymerase (Y-family), little finger domain
(66)
5' to 3' exonuclease catalytic domain
(16)
5' to 3' exonuclease, C-terminal subdomain
(16)
DNA repair protein Rad51, N-terminal domain
(10)
T7 RNA polymerase
(10)
RecA protein-like (ATPase-domain)
(9)
Hef domain-like
(6)
DNA helicase RuvA subunit, N-terminal domain
(5)
DNA helicase RuvA subunit, middle domain
(5)
C-terminal domain of RNA polymerase alpha subunit
(4)
DNA helicase RuvA subunit, C-terminal domain
(4)
Achaeal helicase C-terminal domain
(2)
Adenylation domain of NAD+-dependent DNA ligase
(2)
DNA ligase/mRNA capping enzyme postcatalytic domain
(2)
NAD+-dependent DNA ligase, domain 3
(2)
NusA extra C-terminal domains
(2)
RecQ helicase DNA-binding domain-like
(2)
Tandem AAA-ATPase domain
(2)
XPF/Rad1/Mus81 nuclease
(2)
Excinuclease UvrC C-terminal domain
(1)
Hypothetical protein AF1548, C-terminal domain
(1)
MRR-like
(1)
Sec63 C-terminal domain-like
(1)
Sec63 N-terminal domain
(1)
 
CATH class  (4)
Mainly Alpha
(1223)
Alpha Beta
(1185)
Mainly Beta
(40)
Special
(8)
 
CATH topology  (25)
DNA polymerase; domain 1
(1223)
Beta Polymerase; domain 2
(536)
Alpha-Beta Plaits
(522)
Beta Polymerase; domain 3
(455)
Dna Ligase; domain 1
(340)
MutS, DNA mismatch repair protein, domain I
(337)
Nucleotidyltransferase; domain 5
(179)
Taq DNA Polymerase; Chain T, domain 4
(174)
Rossmann fold
(98)
Sec63 N-terminal domain-like fold
(19)
Helix Hairpins
(16)
Gyrase A; domain 2
(14)
RNA Polymerase Alpha Subunit; Chain A, domain 2
(14)
Immunoglobulin-like
(13)
OB fold (Dihydrolipoamide Acetyltransferase, E2P)
(13)
Arc Repressor Mutant, subunit A
(11)
T7 RNA polymerase; domain 1
(11)
Ferritin
(7)
Helicase, Ruva Protein; domain 3
(7)
YojJ-like (1
(7)
Single alpha-helices involved in coiled-coils or other helix-helix interfaces
(6)
TIM Barrel
(6)
D-amino Acid Aminotransferase; Chain A, domain 1
(5)
Laminin
(2)
Trna Endonuclease; Chain: A, domain 1
(1)
 
Pfam accession / name  (49)
PF14791 : DNA_pol_B_thumb
(536)
PF10391 : DNA_pol_lambd_f
(530)
PF14716 : HHH_8
(523)
PF14792 : DNA_pol_B_palm
(496)
PF00817 : IMS
(337)
PF11799 : IMS_C
(328)
PF00476 : DNA_pol_A
(168)
PF11798 : IMS_HHH
(132)
PF21704 : POLH-Rev1_HhH
(119)
PF22619 : DNA_polI_exo1
(88)
PF21999 : IMS_HHH_1
(75)
PF14520 : HHH_5
(53)
PF09281 : Taq-exonuc
(50)
PF01909 : NTP_transf_2
(34)
PF00752 : XPG_N
(29)
PF00867 : XPG_I
(29)
PF03118 : RNA_pol_A_CTD
(25)
PF08423 : Rad51
(25)
PF02739 : 5_3_exonuc_N
(24)
PF00633 : HHH
(19)
PF01367 : 5_3_exonuc
(18)
PF00270 : DEAD
(14)
PF00271 : Helicase_C
(14)
PF01000 : RNA_pol_A_bac
(14)
PF01193 : RNA_pol_L
(14)
PF01612 : DNA_pol_A_exo1
(13)
PF02889 : Sec63
(13)
PF00940 : RNA_pol
(11)
PF14700 : RPOL_N
(11)
PF01330 : RuvA_N
(9)
PF07499 : RuvA_C
(8)
PF02457 : DAC
(7)
PF10635 : DisA-linker
(7)
PF12826 : HHH_2
(7)
PF09293 : RNaseH_C
(6)
PF01653 : DNA_ligase_aden
(5)
PF02811 : PHP
(5)
PF03119 : DNA_ligase_ZBD
(5)
PF03120 : DNA_ligase_OB
(5)
PF08459 : UvrC_RNaseH_dom
(5)
PF18149 : Helicase_PWI
(5)
PF21188 : BRR2_plug
(5)
PF22745 : Nlig-Ia
(5)
PF02732 : ERCC4
(4)
PF00533 : BRCT
(3)
PF21280 : Helicase_dom4_arc
(3)
PF17949 : PND
(2)
PF04471 : Mrr_cat
(1)
PF22357 : AF1548-like_C
(1)
 
Experimental Information
Diffraction protocol  (2)
Single wavelength
(1123)
MAD
(16)
 
Diffraction radiation source type  (3)
Synchrotron
(782)
Rotating anode
(404)
Sealed tube
(1)
 
Diffraction source  (102)
RIGAKU MICROMAX-007 HF
(165)
RIGAKU RU200
(127)
APS BEAMLINE 22-BM
(100)
APS BEAMLINE 22-ID
(64)
APS BEAMLINE 31-ID
(43)
RIGAKU MICROMAX-007
(43)
SLS BEAMLINE X06SA
(41)
NSLS BEAMLINE X25
(39)
APS BEAMLINE 21-ID-F
(36)
ALS BEAMLINE 5.0.3
(29)
APS BEAMLINE 24-ID-C
(26)
ALS BEAMLINE 12.3.1
(25)
SLS BEAMLINE X06DA
(25)
APS BEAMLINE 21-ID-G
(22)
ESRF BEAMLINE BM14
(20)
SOLEIL BEAMLINE PROXIMA 1
(18)
APS BEAMLINE 17-ID
(16)
RIGAKU RUH3R
(16)
APS BEAMLINE 24-ID-E
(15)
RIGAKU
(14)
APS BEAMLINE 19-ID
(13)
APS BEAMLINE 5ID-B
(13)
NSLS BEAMLINE X29A
(12)
NSRRC BEAMLINE TPS 05A
(12)
APS BEAMLINE 21-ID-D
(11)
CHESS BEAMLINE F1
(11)
NSLS BEAMLINE X12B
(11)
CHESS BEAMLINE A1
(10)
NSLS BEAMLINE X26C
(10)
RIGAKU RU300
(10)
ENRAF-NONIUS
(9)
ESRF BEAMLINE ID23-1
(8)
NSRRC BEAMLINE BL13B1
(8)
APS BEAMLINE 14-BM-C
(7)
ESRF BEAMLINE ID23-2
(7)
NSLS BEAMLINE X12C
(7)
RIGAKU RUH2R
(7)
CLSI BEAMLINE 08ID-1
(6)
NSRRC BEAMLINE BL15A1
(6)
APS BEAMLINE 14-ID-B
(5)
DIAMOND BEAMLINE I03
(5)
ESRF BEAMLINE ID14-4
(5)
NSLS BEAMLINE X6A
(5)
SPRING-8 BEAMLINE BL26B2
(5)
BESSY BEAMLINE 14.2
(4)
ESRF BEAMLINE ID29
(4)
NSLS BEAMLINE X9B
(4)
PHOTON FACTORY BEAMLINE BL-6B
(4)
SPRING-8 BEAMLINE BL32XU
(4)
SPRING-8 BEAMLINE BL38B1
(4)
SSRL BEAMLINE BL7-1
(4)
APS BEAMLINE 19-BM
(3)
DIAMOND BEAMLINE I02
(3)
ESRF BEAMLINE ID14-1
(3)
NSLS BEAMLINE X4A
(3)
NSLS BEAMLINE X4C
(3)
SLS BEAMLINE X10SA
(3)
SSRL BEAMLINE BL9-2
(3)
ALS BEAMLINE 8.2.1
(2)
ALS BEAMLINE 8.2.2
(2)
APS BEAMLINE 23-ID-B
(2)
BRUKER AXS MICROSTAR
(2)
DIAMOND BEAMLINE I04
(2)
MPG/DESY, HAMBURG BEAMLINE BW6
(2)
OTHER
(2)
PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
(2)
PHOTON FACTORY BEAMLINE BL-5A
(2)
RIGAKU RU200HB
(2)
SIEMENS
(2)
SPRING-8 BEAMLINE BL44XU
(2)
SSRL BEAMLINE BL14-1
(2)
ALS BEAMLINE 4.2.2
(1)
ALS BEAMLINE 5.0.1
(1)
ALS BEAMLINE 5.0.2
(1)
ALS BEAMLINE 8.3.1
(1)
APS BEAMLINE 14-BM-D
(1)
APS BEAMLINE 21-ID
(1)
APS BEAMLINE 23-ID-D
(1)
BRUKER D8 QUEST
(1)
CHESS BEAMLINE F2
(1)
DIAMOND BEAMLINE I24
(1)
EMBL/DESY, HAMBURG BEAMLINE X13
(1)
ESRF BEAMLINE BL19
(1)
ESRF BEAMLINE ID14-2
(1)
ESRF BEAMLINE ID14-3
(1)
NSLS BEAMLINE X8C
(1)
NSRRC BEAMLINE BL13C1
(1)
NSRRC BEAMLINE BL17B2
(1)
PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
(1)
PHOTON FACTORY BEAMLINE BL-6A
(1)
RIGAKU FR-E+ SUPERBRIGHT
(1)
SPRING-8
(1)
SPRING-8 BEAMLINE BL12B2
(1)
SPRING-8 BEAMLINE BL41XU
(1)
SPRING-8 BEAMLINE BL45XU
(1)
SRS BEAMLINE PX14.1
(1)
SRS BEAMLINE PX14.2
(1)
SRS BEAMLINE PX9.6
(1)
SSRF BEAMLINE BL17U
(1)
SSRL BEAMLINE BL11-1
(1)
 
More...
 
Synchrotron site  (19)
APS
(378)
NSLS
(93)
SLS
(69)
ALS
(62)
ESRF
(49)
NSRRC
(28)
CHESS
(22)
SOLEIL
(18)
SPring-8
(18)
SSRL
(12)
Diamond
(11)
Photon Factory
(7)
CLSI
(6)
BESSY
(4)
PETRA III, EMBL c/o DESY
(3)
SRS
(3)
MPG/DESY, HAMBURG
(2)
EMBL/DESY, Hamburg
(1)
SSRF
(1)
 
Diffraction detector type  (5)
CCD
(809)
Image plate
(147)
Pixel
(113)
Area detector
(103)
CMOS
(1)
 
Refinement software  (8)
PHENIX
(524)
CNS
(299)
REFMAC
(243)
TNT
(104)
X-PLOR
(35)
BUSTER
(32)
CNX
(2)
PROLSQ
(1)
 
EM microscope model  (2)
FEI TITAN KRIOS
(4)
FEI TITAN
(1)
 
EM detector name  (2)
GATAN K2 SUMMIT (4k x 4k)
(4)
GATAN K2 QUANTUM (4k x 4k)
(1)
 
NMR
NMR software packages  (15)
NMRPipe
(8)
CNS
(6)
CYANA
(5)
NMRView
(5)
Sparky
(5)
Xplor-NIH
(4)
XwinNMR
(4)
X-PLOR
(3)
TopSpin
(2)
ARIA
(1)
CING
(1)
HADDOCK
(1)
PROCHECK / PROCHECK-NMR
(1)
TALOS
(1)
WHAT IF
(1)
 
NMR Field Strength
300.0 - 400
(1)
400.0 - 500
(5)
500.0 - 600
(10)
600.0 - 700
(12)
700.0 - 800
(7)
800.0 - 900
(6)
900.0 - 1000
(3)
 
Representative Structures
Representative Structures
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Entries 1 to 10 of 1224
Entries 1 to 10 of 1224
 Select all entries on this page
Crystal structure of the human FEN1-PCNA complex
Sakurai S, Kitano K, Yamaguchi H, Hamada K, Okada K, Fukuda K, Uchida M, Ohtsuka E, Morioka H, Hakoshima T
EMBO J (2005) [PMID: 15616578  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: MG    MG   
Assembly name: PCNA homotrimer and Flap endonuclease 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-146047 (Preferred)   search this ID
PDBe-KB: P39748    P12004   
X-ray diffraction
2.9Å resolution
Released: 1 Mar 2005
Model geometry
Fit model/data
1ul1
1ul1
1ul1
Divalent metal ions (manganese) bound to T5 5'-exonuclease
Ceska TA, Sayers JR, Suck D
Nat Struct Mol Biol (2004) [PMID: 15077103  ]
Source organism: Escherichia virus T5  
Assembly composition: protein only structure
Bound ligands: MN    MN   
Assembly name: Flap endonuclease (Preferred)   search this complex
PDBe complex ID: PDB-CPX-138947 (Preferred)   search this ID
PDBe-KB: P06229   
X-ray diffraction
2.75Å resolution
Released: 5 Feb 2004
Model geometry
Fit model/data
Data not analysed
1ut5
1ut5
1ut5
T5 5'-EXONUCLEASE MUTANT K83A
Ceska TA, Suck D, Sayers JR
Proc Natl Acad Sci U S A (1999) [PMID: 9874768  ]
Source organism: Escherichia virus T5  
Assembly composition: protein only structure
Assembly name: Flap endonuclease (Preferred)   search this complex
PDBe complex ID: PDB-CPX-138947 (Preferred)   search this ID
PDBe-KB: P06229   
X-ray diffraction
2.5Å resolution
Released: 2 Apr 1999
Model geometry
Fit model/data
Data not deposited
1xo1
1xo1
1xo1
Co-crystal of Bacteriophage T4 RNase H with a fork DNA substrate
Devos JM, Mueser TC
J Biol Chem (2007) [PMID: 17693399  ]
Source organisms: Synthetic construct, Escherichia virus T4  
Assembly composition: DNA/protein complex
Assembly name: Ribonuclease H and DNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-115401 (Preferred)   search this ID
PDBe-KB: P13319   
X-ray diffraction
3Å resolution
Released: 21 Aug 2007
Model geometry
Fit model/data
2ihn
2ihn
2ihn
Divalent metal ions (zinc) bound to T5 5'-exonuclease
Ceska TA, Sayers JR, Suck D
Nat Struct Mol Biol (2004) [PMID: 15077103  ]
Source organism: Escherichia virus T5  
Assembly composition: protein only structure
Bound ligands: ZN    ZN   
Assembly name: Flap endonuclease (Preferred)   search this complex
PDBe complex ID: PDB-CPX-138947 (Preferred)   search this ID
PDBe-KB: P06229   
X-ray diffraction
2.75Å resolution
Released: 5 Feb 2004
Model geometry
Fit model/data
Data not analysed
1ut8
1ut8
1ut8
T5 5'-EXONUCLEASE
Ceska TA, Sayers JR, Stier G, Suck D
Nature (1996) [PMID: 8657312  ]
Source organism: Escherichia virus T5  
Assembly composition: protein only structure
Modified residues: MSE    MSE   
Assembly name: Flap endonuclease (Preferred)   search this complex
PDBe complex ID: PDB-CPX-138947 (Preferred)   search this ID
PDBe-KB: P06229   
X-ray diffraction
2.5Å resolution
Released: 7 Jul 1997
Model geometry
Fit model/data
Data not deposited
1exn
1exn
1exn
FEN-1 FROM P. FURIOSUS
Hosfield DJ, Mol CD, Shen B, Tainer JA
Cell (1998) [PMID: 9778254  ]
Source organism: Pyrococcus furiosus  
Assembly composition: protein only structure
Assembly name: Flap endonuclease 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-131676 (Preferred)   search this ID
PDBe-KB: O93634   
X-ray diffraction
2Å resolution
Released: 12 Jan 2000
Model geometry
Fit model/data
Data not deposited
1b43
1b43
1b43
FLAP ENDONUCLEASE-1 FROM METHANOCOCCUS JANNASCHII
Hwang KY, Baek K, Kim H, Cho Y
Nat Struct Biol (1998) [PMID: 9699635  ]
Assembly composition: protein only structure
Bound ligands: MN    MN   
Assembly name: Flap endonuclease 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-176698 (Preferred)   search this ID
PDBe-KB: Q58839   
X-ray diffraction
2Å resolution
Released: 3 Aug 1999
Model geometry
Fit model/data
Data not deposited
1a76
1a76
1a76
FLAP ENDONUCLEASE-1 FROM METHANOCOCCUS JANNASCHII
Hwang KY, Baek K, Kim H, Cho Y
Nat Struct Biol (1998) [PMID: 9699635  ]
Assembly composition: protein only structure
Bound ligands: MG    MG   
Assembly name: Flap endonuclease 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-176698 (Preferred)   search this ID
PDBe-KB: Q58839   
X-ray diffraction
2Å resolution
Released: 3 Aug 1999
Model geometry
Fit model/data
Data not deposited
1a77
1a77
1a77
Crystal Structure of A. Fulgidus FEN-1 bound to DNA
Chapados BR, Hosfield DJ, Han S, Qiu J, Yelent B, Shen B, Tainer JA
Cell (2004) [PMID: 14718165  ]
Source organisms: Synthetic construct, Archaeoglobus fulgidus  
Assembly composition: DNA/protein complex
Assembly name: Flap endonuclease 1 and DNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-114550 (Preferred)   search this ID
PDBe-KB: O29975   
X-ray diffraction
2.5Å resolution
Released: 27 Jan 2004
Model geometry
Fit model/data
1rxv
1rxv
1rxv
...
Entries 1 to 10 of 1224
Entries 1 to 10 of 1224