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Latest PDB release
Entries released this week
(1)
Entry Information
Entry status
(1)
REL
(210)
Experimental methods
(1)
X-ray diffraction
(210)
Authors
(573)
Carrell RW
(40)
Huntington JA
(37)
Zhou A
(31)
Read RJ
(24)
Whisstock JC
(23)
Wei Z
(22)
Bottomley SP
(20)
Muller YA
(20)
Gardill BR
(19)
Schmidt K
(18)
Stein PE
(17)
Yan Y
(16)
Buckle AM
(15)
Irving JA
(15)
Gettins PG
(13)
Lomas DA
(13)
Li W
(12)
Rossjohn J
(12)
Johnson DJ
(10)
Johnson DJD
(9)
Law RH
(9)
Chan WL
(8)
McGowan S
(8)
Pike RN
(8)
Stanley PL
(8)
Abrahams JP
(7)
Andreasen PA
(7)
Borsch M
(7)
Börsch M
(7)
Gettins PGW
(7)
Kern A
(7)
Kirchweger P
(7)
Pearce MC
(7)
Pei XY
(7)
Qi X
(7)
Volz K
(7)
Yamasaki M
(7)
Baglin TP
(6)
Bashtannyk-Puhalovich TA
(6)
Battaile KP
(6)
Baumann U
(6)
Broughton Pipkin F
(6)
Huang X
(6)
Jensen JK
(6)
Ley SV
(6)
Loiseau F
(6)
Lovell S
(6)
Michel K
(6)
Milroy LG
(6)
Murphy MP
(6)
Myers RM
(6)
Pipkin FB
(6)
Skinner R
(6)
Smith AI
(6)
Zhang X
(6)
Adams TE
(5)
An C
(5)
Curmi PM
(5)
Dementiev A
(5)
Feil SC
(5)
Gooptu B
(5)
Harrop SJ
(5)
Huber R
(5)
Kan WT
(5)
Kanost MR
(5)
Langdown J
(5)
Mccoy AJ
(5)
Meekins DA
(5)
Parker MW
(5)
Simonovic M
(5)
Zhang Q
(5)
Abrahams J-P
(4)
Brunstein E
(4)
Bulynko YA
(4)
Cabrita LD
(4)
Dai W
(4)
Declerck PJ
(4)
Drogemuller C
(4)
Drögemüller C
(4)
Esmon CT
(4)
Gebauer JM
(4)
Grigoryev SA
(4)
Hansen G
(4)
Heiker JT
(4)
Henderson KN
(4)
Hoke DE
(4)
Jankova L
(4)
Kass I
(4)
Laurell CB
(4)
Leeb T
(4)
Luis SA
(4)
Ma L
(4)
Marijanovic EM
(4)
McCoy AJ
(4)
Olson ST
(4)
Ong PC
(4)
Popova EY
(4)
Porebski BT
(4)
Rosenbaum S
(4)
Ruzyla K
(4)
More...
Homo / hetero assembly
(2)
homo
(123)
hetero
(87)
Assembly composition
(2)
protein structure
(123)
protein/protein complex
(87)
Assembly polymer count
(6)
monomer
(112)
dimer
(74)
trimer
(15)
pentamer
(4)
tetramer
(4)
hexamer
(1)
Resolution distribution
1.0 - 1.5
(10)
1.5 - 2
(57)
2.0 - 2.5
(57)
2.5 - 3
(67)
3.0 - 3.5
(17)
3.5 - 4
(2)
Release year distribution
1985 - 1990
(3)
1990 - 1995
(9)
1995 - 2000
(32)
2000 - 2005
(46)
2005 - 2010
(61)
2010 - 2015
(63)
2015 - 2020
(44)
Journal
(32)
J Biol Chem
(46)
J Mol Biol
(28)
Proc Natl Acad Sci U S A
(21)
To be published
(15)
J Struct Biol
(13)
Protein Sci
(9)
Structure
(9)
Blood
(8)
Nature
(8)
Biochemistry
(6)
Nat Struct Biol
(6)
Sci Rep
(6)
EMBO J
(5)
EMBO Rep
(3)
Protein Eng
(3)
BMC Struct Biol
(2)
Biochem Biophys Rep
(2)
Biochem J
(2)
FEBS Lett
(2)
Nat Struct Mol Biol
(2)
PLoS One
(2)
Acta Crystallogr D Biol Crystallogr
(1)
Acta Crystallogr F Struct Biol Commun
(1)
Acta Crystallogr Sect F Struct Biol Cryst Commun
(1)
Biochem Biophys Res Commun
(1)
Biol Chem
(1)
Cell Mol Life Sci
(1)
Int J Mol Med
(1)
J Immunol
(1)
J Thromb Haemost
(1)
J. Biol. Chem.
(1)
Proteins
(1)
Macromolecules
Organism superkingdom
(3)
Eukaryota
(197)
Bacteria
(6)
Viruses
(3)
Organism name
(24)
Homo sapiens
(154)
Mus musculus
(8)
Gallus gallus
(7)
Anopheles gambiae
(6)
Canis lupus familiaris
(4)
synthetic construct
(4)
Caldanaerobacter subterraneus subsp. tengcongensis MB4
(3)
Cowpox virus
(3)
Rattus norvegicus
(3)
Drosophila melanogaster
(2)
Manduca sexta
(2)
Thermobifida fusca
(2)
Arabidopsis thaliana
(1)
Bombyx mori
(1)
Bos taurus
(1)
Danio rerio
(1)
Equus caballus
(1)
Ixodes ricinus
(1)
Lampetra fluviatilis
(1)
Oncorhynchus mykiss
(1)
Schistosoma haematobium
(1)
Taeniopygia guttata
(1)
Tannerella forsythia 92A2
(1)
Tenebrio molitor
(1)
Molecule name
(174)
ATIII
(28)
Alpha-1 protease inhibitor
(28)
Alpha-1-antiproteinase
(28)
Alpha-1-antitrypsin
(28)
Antithrombin-III
(28)
SPAAT
(28)
Serpin A1
(28)
Serpin C1
(28)
Short peptide from AAT
(28)
Endothelial plasminogen activator inhibitor
(26)
Plasminogen activator inhibitor 1
(26)
Serpin E1
(26)
ACT
(24)
Alpha-1-antichymotrypsin
(24)
Alpha-1-antichymotrypsin His-Pro-less
(24)
Cell growth-inhibiting gene 24/25 protein
(24)
PAI
(24)
PAI-1
(24)
Serpin A3
(24)
Serpin domain-containing protein
(15)
Serpin A7
(9)
T4-binding globulin
(9)
Thyroxine-binding globulin
(9)
Ang I
(6)
Ang II
(6)
Ang III
(6)
Ang IV
(6)
Angiotensin 1-10
(6)
Angiotensin 1-4
(6)
Angiotensin 1-5
(6)
Angiotensin 1-7
(6)
Angiotensin 1-8
(6)
Angiotensin 1-9
(6)
Angiotensin 2-8
(6)
Angiotensin 3-8
(6)
Angiotensin I
(6)
Angiotensin II
(6)
Angiotensin III
(6)
Angiotensin IV
(6)
Angiotensin-1
(6)
Angiotensin-2
(6)
Angiotensin-3
(6)
Angiotensin-4
(6)
Angiotensinogen
(6)
CBG
(6)
Corticosteroid-binding globulin
(6)
Des-Asp[1]-angiotensin II
(6)
Serpin A6
(6)
Serpin A8
(6)
Transcortin
(6)
PCI
(5)
PZ-dependent protease inhibitor
(5)
PZI
(5)
Plasma serine protease inhibitor
(5)
Protein C inhibitor
(5)
Protein Z-dependent protease inhibitor
(5)
Serine protease inhibitor
(5)
Serine protease inhibitor 2
(5)
Serpin 2
(5)
Serpin A10
(5)
Serpin A5
(5)
Acrosomal serine protease inhibitor
(4)
Heterochromatin-associated protein MENT
(4)
Maspin
(4)
Monocyte Arg-serpin
(4)
Myeloid and erythroid nuclear termination stage-specific protein
(4)
Neuroserpin
(4)
OL-64
(4)
PAI-2
(4)
PAI-3
(4)
PAI3
(4)
PI-12
(4)
PI-5
(4)
Peptidase inhibitor 12
(4)
Peptidase inhibitor 5
(4)
Placental plasminogen activator inhibitor
(4)
Plasminogen activator inhibitor 2
(4)
Plasminogen activator inhibitor 3
(4)
Serpin A12
(4)
Serpin B10
(4)
Serpin B2
(4)
Serpin B5
(4)
Serpin I1
(4)
Urokinase inhibitor
(4)
Vaspin
(4)
Visceral adipose tissue-derived serine protease inhibitor
(4)
Visceral adipose-specific serpin
(4)
Allergen Gal d II
(3)
Collagen-binding protein
(3)
Cytokine response modifier protein A
(3)
Egg albumin
(3)
Hemorrhage-inducing 38 kDa protein
(3)
ICE inhibitor
(3)
Kallikrein inhibitor
(3)
Kallistatin
(3)
Ovalbumin
(3)
PI-4
(3)
Peptidase inhibitor 4
(3)
Plakalbumin
(3)
Protein T4-A
(3)
More...
Molecule type
(1)
Protein
(210)
Gene names
(112)
1270169
(5)
3290412
(1)
100272183
(1)
AAT
(28)
AT3
(28)
PI
(28)
PRO0684
(28)
PRO2209
(28)
SERPINA1
(28)
SERPINC1
(28)
PRO0309
(27)
PAI1
(25)
PLANH1
(25)
AACT
(24)
GIG24
(24)
GIG25
(24)
SERPINA3
(24)
SERPINE1
(23)
SERPINA7
(9)
TBG
(9)
AgaP_AGAP006911
(5)
Agt
(5)
CBG
(5)
SERPINA5
(5)
SERPINA6
(5)
SRPN2
(5)
Serpina8
(5)
MENT
(4)
PAI2
(4)
PCI
(4)
PI5
(4)
PLANH2
(4)
PLANH3
(4)
PROCI
(4)
SERPINA10
(4)
SERPINA12
(4)
SERPINB10
(4)
SERPINB2
(4)
SERPINB5
(4)
UNQ707/PRO1358
(4)
ZPI
(4)
CPXV207
(3)
KST
(3)
OPG199
(3)
PI12
(3)
PI4
(3)
SCCA
(3)
SCCA1
(3)
SERPINA4
(3)
SERPINB14
(3)
SERPINB3
(3)
SERPINH1
(3)
SERPINI1
(3)
SPI-2
(3)
TTE1560
(3)
CG9453
(2)
Dmel\CG9453
(2)
Dmel_CG9453
(2)
ELANH2
(2)
HCF2
(2)
PAI
(2)
PAI-1
(2)
PI7
(2)
PN1
(2)
SERPINB1
(2)
SERPIND1
(2)
SERPINE2
(2)
Serp2
(2)
Sp4
(2)
Spn4
(2)
Spn42Da
(2)
Spn4A
(2)
Tfu_1933
(2)
dSerp2
(2)
serpine1
(2)
sp4
(2)
spn4
(2)
AGT
(1)
AgaP_AGAP007691
(1)
At1g47710
(1)
BFO_3114
(1)
C1IN
(1)
C1NH
(1)
Cbg
(1)
F16N3.3
(1)
MNEI
(1)
Mr1
(1)
PEDF
(1)
PI2
(1)
PIG35
(1)
Pai1
(1)
Pi12
(1)
Planh1
(1)
Pli
(1)
SERPINA8
(1)
SERPINF1
(1)
SERPING1
(1)
SPN48
(1)
SRPN18
(1)
Serpina10
(1)
More...
Interacting Molecules
(44)
Alpha-1-antichymotrypsin His-Pro-less
(21)
Short peptide from AAT
(9)
Thyroxine-binding globulin
(7)
Thrombin heavy chain
(6)
Thrombin light chain
(6)
Plasminogen activator inhibitor 2
(3)
Serine proteinase inhibitor 2
(3)
Antithrombin-III
(2)
Collagen alpha-1(XXVI) chain
(2)
Heterochromatin-associated protein MENT
(2)
Kallistatin
(2)
Neuroserpin
(2)
Plasma serine protease inhibitor
(2)
Protein Z-dependent protease inhibitor
(2)
Serine protease 1
(2)
Serpin domain-containing protein
(2)
Tissue-type plasminogen activator chain B
(2)
Vitamin K-dependent protein Z
(2)
ACE-THR-THR-ALA-ILE-NH2
(1)
Activated factor Xa heavy chain
(1)
Anionic trypsin-2
(1)
Antithrombin P14-P9 peptide
(1)
COLLAGEN MODEL PEPTIDE 18-T8R11
(1)
Chymotrypsin-like elastase family member 1
(1)
Coagulation factor IXa heavy chain
(1)
Coagulation factor IXa light chain
(1)
Corticosteroid-binding globulin
(1)
EXOGENOUS TRIPEPTIDE formyl-(NLE)LF
(1)
Factor X light chain
(1)
HEAVY CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY
(1)
LIGHT CHAIN OF FAB FRAGMENT FROM AN PAI-1 ANTIBODY
(1)
Leukocyte elastase inhibitor
(1)
Ovalbumin
(1)
P14-P8 reactive loop peptide
(1)
PENTAPEPTIDE
(1)
PROTEIN (PEPTIDE)
(1)
Plasminogen activator inhibitor 1
(1)
SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47 ), MEMBER 1, (COLLAGEN BINDING PROTEIN 1)
(1)
SERPYIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47 ), MEMBER 1, (COLLAGEN BINDING PROTEIN 1)
(1)
Somatomedin-B
(1)
Urokinase-type plasminogen activator chain B
(1)
antithrombin P14-P9 peptide
(1)
exogenous Cholecystokinin tetrapeptide
(1)
exogenous tripeptide formyl-MLF
(1)
Interacting ligands
(82)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(40)
GOL : GLYCEROL
(30)
EDO : 1,2-ETHANEDIOL
(26)
SO4 : SULFATE ION
(20)
MAN : alpha-D-mannopyranose
(15)
BMA : beta-D-mannopyranose
(13)
CL : CHLORIDE ION
(12)
NA : SODIUM ION
(9)
CA : CALCIUM ION
(8)
GU6 : 2,3,6-tri-O-sulfo-alpha-D-glucopyranose
(7)
GU1 : 2,3-di-O-methyl-beta-D-glucopyranuronic acid
(6)
HCY : (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
(6)
PO4 : PHOSPHATE ION
(5)
T44 : 3,5,3',5'-TETRAIODO-L-THYRONINE
(5)
Z9K : 3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid
(5)
Z9L : methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside
(5)
CIT : CITRIC ACID
(4)
CYS : CYSTEINE
(4)
IDS : 2-O-sulfo-alpha-L-idopyranuronic acid
(4)
PRD_900031 : heparin pentasaccharide
(4)
SGN : 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose
(4)
Z9H : 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose
(4)
ZN : ZINC ION
(4)
ACT : ACETATE ION
(3)
BME : BETA-MERCAPTOETHANOL
(3)
FUC : alpha-L-fucopyranose
(3)
GU8 : 2,3,6-tri-O-methyl-beta-D-glucopyranose
(3)
MPD : (4S)-2-METHYL-2,4-PENTANEDIOL
(3)
NDG : 2-acetamido-2-deoxy-alpha-D-glucopyranose
(3)
96P : (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate)
(2)
BDP : beta-D-glucopyranuronic acid
(2)
DM2 : DOXORUBICIN
(2)
DXT : (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE
(2)
FLC : CITRATE ANION
(2)
GU0 : 2,3,6-tri-O-sulfonato-beta-D-glucopyranose
(2)
GU2 : 2,3-di-O-methyl-alpha-L-idopyranuronic acid
(2)
GU3 : methyl 3-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranoside
(2)
GU4 : 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose
(2)
GU5 : 2,3-di-O-methyl-6-O-sulfonato-alpha-D-glucopyranose
(2)
GU9 : 2,3,6-tri-O-methyl-alpha-D-glucopyranose
(2)
PRD_900028 : fondaparinux
(2)
STR : PROGESTERONE
(2)
SUS : 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose
(2)
ZDO : methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside
(2)
1PE : PENTAETHYLENE GLYCOL
(1)
ACY : ACETIC ACID
(1)
AS4 : ALDOSTERONE
(1)
BDG : 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranose
(1)
C0R : CORTICOSTERONE
(1)
DMS : DIMETHYL SULFOXIDE
(1)
DTT : 2,3-DIHYDROXY-1,4-DITHIOBUTANE
(1)
EMJ : 2,5-dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione
(1)
F6Y : 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-6-CARBOXYLIC ACID
(1)
F6Z : 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-5-CARBOXYLIC ACID
(1)
FOR : FORMYL GROUP
(1)
FUL : beta-L-fucopyranose
(1)
FUN : 5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID
(1)
GAL : beta-D-galactopyranose
(1)
GDE : 3,4,5-trihydroxybenzoic acid
(1)
GLC : alpha-D-glucopyranose
(1)
GUP : alpha-L-gulopyranose
(1)
ID8 : 2-[(2,3-DIMETHYLPHENYL)AMINO]BENZOIC ACID
(1)
IMN : INDOMETHACIN
(1)
IOD : IODIDE ION
(1)
IPA : ISOPROPYL ALCOHOL
(1)
MLA : MALONIC ACID
(1)
NAA : 2-acetamido-2-deoxy-beta-D-allopyranose
(1)
NI : NICKEL (II) ION
(1)
NO3 : NITRATE ION
(1)
OXM : OXAMIC ACID
(1)
PEG : DI(HYDROXYETHYL)ETHER
(1)
PRD_900079 : heparin heptasaccharide
(1)
RIP : beta-D-ribopyranose
(1)
SIN : SUCCINIC ACID
(1)
TB7 : TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE
(1)
TES : TESTOSTERONE
(1)
U9D : 4-deoxy-2,3,6-tri-O-methyl-alpha-D-xylo-hexopyranose
(1)
U9G : 2,3-di-O-methyl-6-O-sulfo-alpha-D-glucopyranose
(1)
U9J : (2R,3R,4S,5S,6R)-6-(dihydroxymethyl)-3,4-dimethoxytetrahydro-2H-pyran-2,5-diol
(1)
U9M : (2R,3R,4S,5S,6S)-6-(dihydroxymethyl)-3,4-dimethoxytetrahydro-2H-pyran-2,5-diol
(1)
YYB : 1,5-anhydro-3-O-methyl-2,6-di-O-sulfo-D-glucitol
(1)
Z6W : (5R)-5-[(2R)-2-hydroxynonyl]-beta-D-xylulofuranose
(1)
Function and Biology
Biological function
(28)
serine-type endopeptidase inhibitor activity
(210)
peptidase inhibitor activity
(135)
protein binding
(120)
protease binding
(73)
identical protein binding
(46)
heparin binding
(39)
DNA binding
(24)
endopeptidase inhibitor activity
(24)
signaling receptor binding
(23)
cysteine-type endopeptidase inhibitor activity
(6)
type 1 angiotensin receptor binding
(6)
type 2 angiotensin receptor binding
(6)
lipid binding
(5)
receptor ligand activity
(5)
steroid binding
(5)
collagen binding
(4)
glycosaminoglycan binding
(4)
molecular carrier activity
(4)
molecular function inhibitor activity
(4)
chromatin DNA binding
(3)
growth factor activity
(3)
hormone activity
(3)
phosphatidylcholine binding
(3)
retinoic acid binding
(3)
virus receptor activity
(3)
acrosin binding
(2)
protein homodimerization activity
(1)
toxin activity
(1)
Biological process
(262)
blood coagulation
(56)
hemostasis
(54)
acute-phase response
(43)
negative regulation of proteolysis
(31)
regulation of blood coagulation
(28)
negative regulation of plasminogen activation
(26)
fibrinolysis
(25)
negative regulation of blood coagulation
(23)
negative regulation of fibrinolysis
(23)
negative regulation of vascular wound healing
(23)
angiogenesis
(22)
defense response to Gram-negative bacterium
(22)
negative regulation of cell migration
(22)
positive regulation of angiogenesis
(22)
positive regulation of coagulation
(22)
positive regulation of inflammatory response
(22)
response to cytokine
(22)
cellular response to lipopolysaccharide
(21)
dentinogenesis
(21)
inflammatory response
(21)
maintenance of gastrointestinal epithelium
(21)
negative regulation of cell adhesion mediated by integrin
(21)
negative regulation of endothelial cell apoptotic process
(21)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
(21)
negative regulation of integrin-mediated signaling pathway
(21)
negative regulation of smooth muscle cell migration
(21)
negative regulation of smooth muscle cell-matrix adhesion
(21)
negative regulation of thrombin-activated receptor signaling pathway
(21)
negative regulation of wound healing
(21)
positive regulation of blood coagulation
(21)
positive regulation of interleukin-8 production
(21)
positive regulation of leukotriene production involved in inflammatory response
(21)
positive regulation of monocyte chemotaxis
(21)
positive regulation of odontoblast differentiation
(21)
positive regulation of receptor-mediated endocytosis
(21)
regulation of lipid metabolic process
(21)
replicative senescence
(21)
extracellular matrix organization
(9)
negative regulation of endopeptidase activity
(9)
negative regulation of protein processing
(9)
positive regulation of epithelial to mesenchymal transition
(9)
regulation of immune response
(8)
kidney development
(7)
negative regulation of cell population proliferation
(7)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
(7)
G protein-coupled receptor signaling pathway
(6)
angiotensin-activated signaling pathway
(6)
blood vessel diameter maintenance
(6)
immune system process
(6)
positive regulation of cytokine production
(6)
positive regulation of insulin receptor signaling pathway
(6)
regulation of apoptotic process
(6)
regulation of blood pressure
(6)
regulation of renal output by angiotensin
(6)
regulation of systemic arterial blood pressure by renin-angiotensin
(6)
renin-angiotensin regulation of aldosterone production
(6)
vasoconstriction
(6)
MAPK cascade
(5)
adenylate cyclase-activating G protein-coupled receptor signaling pathway
(5)
aldosterone secretion
(5)
angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
(5)
angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure
(5)
astrocyte activation
(5)
blood vessel development
(5)
brain renin-angiotensin system
(5)
branching involved in ureteric bud morphogenesis
(5)
cell population proliferation
(5)
cell-matrix adhesion
(5)
defense response to protozoan
(5)
drinking behavior
(5)
establishment of blood-nerve barrier
(5)
glucocorticoid metabolic process
(5)
hormone metabolic process
(5)
innate immune response
(5)
negative regulation of melanization defense response
(5)
negative regulation of neuron apoptotic process
(5)
negative regulation of smooth muscle cell proliferation
(5)
negative regulation of vascular associated smooth muscle cell proliferation
(5)
neuron apoptotic process
(5)
organ growth
(5)
ovarian follicle rupture
(5)
peristalsis
(5)
positive regulation of MAPK cascade
(5)
positive regulation of canonical NF-kappaB signal transduction
(5)
positive regulation of cell population proliferation
(5)
positive regulation of fatty acid biosynthetic process
(5)
positive regulation of gene expression
(5)
positive regulation of insulin secretion involved in cellular response to glucose stimulus
(5)
positive regulation of multicellular organism growth
(5)
positive regulation of neuron projection development
(5)
positive regulation of organ growth
(5)
regulation of gene expression
(5)
regulation of inflammatory response
(5)
regulation of systemic arterial blood pressure by circulatory renin-angiotensin
(5)
renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure
(5)
response to cold
(5)
response to salt stress
(5)
smooth muscle cell differentiation
(5)
smooth muscle cell proliferation
(5)
vascular associated smooth muscle cell proliferation
(5)
More...
Biological cell component
(65)
extracellular space
(210)
extracellular region
(145)
extracellular exosome
(111)
collagen-containing extracellular matrix
(96)
platelet alpha granule lumen
(62)
plasma membrane
(58)
endoplasmic reticulum lumen
(52)
blood microparticle
(48)
nucleus
(27)
azurophil granule lumen
(24)
secretory granule lumen
(24)
endoplasmic reticulum
(23)
peptidase inhibitor complex
(22)
serine protease inhibitor complex
(22)
COPII-coated ER to Golgi transport vesicle
(20)
Golgi apparatus
(20)
endoplasmic reticulum-Golgi intermediate compartment membrane
(20)
ficolin-1-rich granule lumen
(20)
intracellular membrane-bounded organelle
(20)
cytoplasm
(14)
cornified envelope
(8)
cytoplasmic vesicle
(5)
cytosol
(5)
platelet alpha granule
(5)
sarcoplasm
(4)
acrosomal membrane
(3)
chromatin
(3)
chromosome
(3)
collagen trimer
(3)
membrane
(3)
neuronal cell body
(3)
nucleoplasm
(3)
platelet dense tubular network
(3)
protein C inhibitor-KLK3 complex
(3)
protein C inhibitor-PLAT complex
(3)
protein C inhibitor-PLAU complex
(3)
protein C inhibitor-TMPRSS11E complex
(3)
protein C inhibitor-TMPRSS7 complex
(3)
protein C inhibitor-coagulation factor V complex
(3)
protein C inhibitor-coagulation factor XI complex
(3)
protein C inhibitor-coagulation factor Xa complex
(3)
protein C inhibitor-plasma kallikrein complex
(3)
protein C inhibitor-thrombin complex
(3)
vesicle
(3)
cytolytic granule
(2)
cytoplasmic vesicle lumen
(2)
early endosome
(2)
endosome
(2)
external side of plasma membrane
(2)
extracellular vesicle
(2)
lysosome
(2)
mitochondrion
(2)
neuromuscular junction
(2)
perikaryon
(2)
protein-containing complex
(2)
apoplast
(1)
axon
(1)
axon hillock
(1)
basement membrane
(1)
cell surface
(1)
cytoplasmic ribonucleoprotein granule
(1)
fibrinogen complex
(1)
melanosome
(1)
perinuclear region of cytoplasm
(1)
platelet dense granule lumen
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
...
Entries 1 to 10 of 210
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Structure of the native serpin-type proteinase inhibitor, miropin.
Goulas T, Ksiazek M, Garcia-Ferrer I, Mizgalska D, Potempa J, Gomis-Ruth X
J Biol Chem
(2017)
[PMID: 28512127 ]
Source organism: Tannerella forsythia 92A2
Assembly composition: protein only structure
Assembly name:
Serpin domain-containing protein
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-124643 (Preferred)
search this ID

Structure of tPA and PAI-1
Min L, Huang M
To be published
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Bound ligands:
GOL
Assembly name:
tPA-PAI-1 complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-133301 (Preferred)
search this ID
Structure of reaction loop cleaved lamprey angiotensinogen
Wei H, Zhou A
J Biol Chem
(2016)
[PMID: 27681598 ]
Source organism: Lampetra fluviatilis
Assembly composition: protein/protein complex
Bound ligands:
SO4
Assembly name:
Serpin domain-containing protein
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-111029 (Preferred)
search this ID

Crystal structure of Alpha1-antichymotrypsin variant DBS-I-allo1: an allosterically triggered drug-binding serpin for doxycycline
Schmidt K, Muller YA
Proc Natl Acad Sci U S A
(2018)
[PMID: 29760101 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Alpha-1-antichymotrypsin His-Pro-less
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-133792 (Preferred)
search this ID
Crystal structure of Alpha1-antichymotrypsin variant DBS-I-allo2: a MMP9-cleavable drug-binding serpin for doxycycline
Schmidt K, Muller YA
Proc Natl Acad Sci U S A
(2018)
[PMID: 29760101 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Alpha-1-antichymotrypsin His-Pro-less
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-133792 (Preferred)
search this ID
Michaelis complex of tPA-S195A:PAI-1
Gong L
J Biol Chem
(2015)
[PMID: 26324706 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
tPA-PAI-1 complex
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-133301 (Preferred)
search this ID
Crystal form 2 of Alpha1-antichymotrypsin variant DBS-II-allo: an allosterically modulated drug-binding serpin for doxorubicin
Schmidt K, Muller YA
Proc Natl Acad Sci U S A
(2018)
[PMID: 29760101 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Alpha-1-antichymotrypsin His-Pro-less
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-133792 (Preferred)
search this ID
Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations
Huntington JA, Pomowski A, Johnson DJD
To be published
Source organism: Homo sapiens
Assembly composition: protein only structure
Bound ligands:
GOL
Assembly name:
Alpha-1-antitrypsin
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-133784 (Preferred)
search this ID

Crystal structure of Alpha1-antichymotrypsin variant DBS-I1: a drug-binding serpin for doxycycline
Schmidt K, Muller YA
Proc Natl Acad Sci U S A
(2018)
[PMID: 29760101 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Alpha-1-antichymotrypsin His-Pro-less
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-133792 (Preferred)
search this ID
Crystal structure of conserpin in the latent state
Porebski BT, McGowan S, Keleher S, Buckle AM
Sci Rep
(2016)
[PMID: 27667094 ]
Source organism: synthetic construct
Assembly composition: protein only structure
Bound ligands:
GOL
Assembly name:
Conserpin in the latent state
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-165491 (Preferred)
search this ID
...
Entries 1 to 10 of 210