Entries released this week  (1)

revised

(1)

Entry status  (1)

REL

(307)

Experimental methods  (3)

X-ray diffraction

(276)

Solution NMR

(27)

Electron Microscopy

(4)

Authors  (1648)

Williams RL

(44)

Sudhof TC

(23)

Südhof TC

(23)

Nonomiya J

(19)

Pang J

(19)

Salphati L

(19)

Shokat KM

(19)

Perisic O

(18)

Tang J

(18)

Lewis C

(17)

Rizo J

(17)

Williams O

(17)

Yakowec P

(17)

Berndt A

(16)

Murray JM

(16)

Rommel C

(16)

Ruckle T

(16)

Rückle T

(16)

Schwarz MK

(16)

Gorrec F

(15)

Hon W-C

(15)

Hon WC

(15)

Lesnick J

(15)

Miller S

(15)

Whittington DA

(15)

Gaillard P

(14)

Houseman BT

(14)

Le DD

(14)

Lee DD

(14)

Liu Y

(14)

Pacold JI

(14)

Shaw JP

(14)

Sutherlin DP

(14)

RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(13)

Tomchick DR

(13)

Tsui V

(13)

Yokoyama S

(13)

Hayashi F

(12)

Nagashima T

(12)

Prior WW

(12)

Sampath D

(12)

Wang L

(12)

Wymann MP

(12)

Olivero AG

(11)

Staben ST

(11)

Wei B

(11)

Wiesmann C

(11)

Dotson J

(10)

Essen LO

(10)

Igumenova TI

(10)

Mullady EL

(10)

Sutton RB

(10)

Chen Y

(9)

Cheng H

(9)

Corbalan-Garcia S

(9)

Gomez-Fernandez JC

(9)

Hawkins PT

(9)

Heffron TP

(9)

Knapp MS

(9)

Knighton DR

(9)

Verdaguer N

(9)

Brunger AT

(8)

Castanedo G

(8)

Elling RA

(8)

Essen L-O

(8)

Goldsmith R

(8)

Gómez-Fernández JC

(8)

Katan M

(8)

Lee L

(8)

Machius M

(8)

McCarter JD

(8)

Pacold ME

(8)

Price S

(8)

San Miguel T

(8)

Sideris S

(8)

Stephens L

(8)

Walker EH

(8)

Wan NC

(8)

Zalameda L

(8)

Zhang N

(8)

Zhu BY

(8)

Cardozo M

(7)

Corbalán-García S

(7)

Cushing TD

(7)

Do S

(7)

Ferrer-Orta C

(7)

Friedman L

(7)

He X

(7)

Liu KK

(7)

Liu L

(7)

McGee LR

(7)

Medina JC

(7)

Mohn D

(7)

Olivero A

(7)

Rouge L

(7)

Shin Y

(7)

Trapani JA

(7)

Voskoboinik I

(7)

Wahl MC

(7)

Wang S

(7)

 

More...

Homo / hetero assembly  (2)

homo

(260)

hetero

(47)

Assembly composition  (3)

protein structure

(260)

protein/protein complex

(43)

RNA/protein complex

(4)

Assembly polymer count  (12)

monomer

(249)

dimer

(42)

heptamer

(3)

pentamer

(3)

dodecamer

(2)

trimer

(2)

34-mer

(1)

35-mer

(1)

45-mer

(1)

hexamer

(1)

tetramer

(1)

undecamer

(1)

Resolution distribution

0.5 - 1

(1)

1.0 - 1.5

(18)

1.5 - 2

(61)

2.0 - 2.5

(59)

2.5 - 3

(111)

3.0 - 3.5

(22)

3.5 - 4

(6)

4.0 - 4.5

(1)

9.5 - 10

(1)

Release year distribution

1990 - 1995

(1)

1995 - 2000

(27)

2000 - 2005

(29)

2005 - 2010

(90)

2010 - 2015

(151)

2015 - 2020

(73)

Journal  (46)

To be published

(45)

Bioorg Med Chem Lett

(37)

J Med Chem

(37)

Nat Chem Biol

(17)

J Biol Chem

(15)

Biochemistry

(14)

Proc Natl Acad Sci U S A

(13)

Structure

(13)

ACS Med Chem Lett

(12)

Nat Struct Mol Biol

(12)

Nature

(11)

Cell

(9)

Mol Cell

(9)

J Mol Biol

(6)

Protein Sci

(6)

J Am Chem Soc

(3)

Metallomics

(3)

Science

(3)

ACS Chem Biol

(2)

Biochem Biophys Res Commun

(2)

Biochem J

(2)

Biophys J

(2)

Cell Death Differ

(2)

Cell Rep

(2)

ChemMedChem

(2)

Elife

(2)

Int J Biol Macromol

(2)

Nat Commun

(2)

Nat Med

(2)

Nat Struct Biol

(2)

Oncotarget

(2)

PLoS Biol

(2)

Acta Crystallogr D Biol Crystallogr

(1)

Brain

(1)

Cell Cycle

(1)

EMBO J

(1)

Genes Dev

(1)

J Cell Biol

(1)

J Chem Inf Model

(1)

J Neurosci

(1)

J Struct Biol

(1)

Mol Cancer Ther

(1)

Nat Cell Biol

(1)

Neuron

(1)

Oncogene

(1)

PLoS One

(1)

Organism superkingdom  (1)

Eukaryota

(307)

Organism name  (15)

Homo sapiens

(181)

Rattus norvegicus

(60)

Mus musculus

(42)

Saccharomyces cerevisiae

(5)

Sus scrofa

(5)

Danio rerio

(2)

Rattus rattus

(2)

Saccharomyces cerevisiae S288C

(2)

Scophthalmus maximus

(2)

Arabidopsis thaliana

(1)

Chaetomium thermophilum

(1)

Doryteuthis pealeii

(1)

Drosophila melanogaster

(1)

Gallus gallus

(1)

Sepia officinalis

(1)

Molecule name  (226)

PI3-kinase subunit gamma

(96)

PI3K-gamma

(96)

PI3Kgamma

(96)

Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma

(96)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

(96)

Phosphoinositide-3-kinase catalytic gamma polypeptide

(96)

PtdIns-3-kinase subunit gamma

(96)

PtdIns-3-kinase subunit p110-gamma

(96)

Serine/threonine protein kinase PIK3CG

(96)

p110gamma

(96)

p120-PI3K

(96)

Synaptotagmin I

(33)

Synaptotagmin-1

(33)

SytI

(33)

p65

(33)

PI3-kinase subunit delta

(25)

PI3K-delta

(25)

PI3Kdelta

(25)

Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta

(25)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

(25)

PtdIns-3-kinase subunit delta

(25)

PtdIns-3-kinase subunit p110-delta

(25)

p110delta

(25)

PI3-kinase subunit alpha

(20)

PI3K-alpha

(20)

PI3Kalpha

(20)

Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha

(20)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

(20)

Phosphoinositide-3-kinase catalytic alpha polypeptide

(20)

PtdIns-3-kinase subunit alpha

(20)

PtdIns-3-kinase subunit p110-alpha

(20)

Serine/threonine protein kinase PIK3CA

(20)

p110alpha

(20)

Phosphoinositide 3-kinase alpha

(19)

Exophilin-1

(11)

Rabphilin-3A

(11)

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

(10)

PLC-III

(10)

PLC-delta-1

(10)

Phosphoinositide phospholipase C-delta-1

(10)

Phospholipase C-III

(10)

Phospholipase C-delta-1

(10)

PKC-A

(8)

PKC-alpha

(8)

Protein kinase C alpha type

(8)

Pre-mRNA-splicing helicase BRR2

(7)

Protein Snu246

(7)

Activating signal cointegrator 1 complex subunit 3-like 1

(5)

BRR2 homolog

(5)

Cytolysin

(5)

HBeAg-binding protein 3

(5)

KIBRA

(5)

Kidney and brain protein

(5)

Lymphocyte pore-forming protein

(5)

P1

(5)

Perforin-1

(5)

Protein KIBRA

(5)

U5 small nuclear ribonucleoprotein 200 kDa helicase

(5)

U5 snRNP-specific 200 kDa protein

(5)

U5-200KD

(5)

WW domain-containing protein 1

(5)

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

(4)

Chr2Syt

(4)

Cytosolic phospholipase A2

(4)

E-Syt2

(4)

Extended synaptotagmin-2

(4)

Lysophospholipase

(4)

Munc13-1

(4)

PI3K-C2-alpha

(4)

PLC-beta-3

(4)

Phosphatidylcholine 2-acylhydrolase

(4)

Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

(4)

Phosphoinositide 3-kinase-C2-alpha

(4)

Phosphoinositide phospholipase C-beta-3

(4)

Phospholipase A2

(4)

Phospholipase A2 group IVA

(4)

Phospholipase C-beta-3

(4)

Protein unc-13 homolog A

(4)

PtdIns-3-kinase C2 subunit alpha

(4)

cPLA2

(4)

Centrosomal protein of 120 kDa

(3)

Cep120

(3)

Coiled-coil domain-containing protein 100

(3)

Synaptotagmin IV

(3)

Synaptotagmin VII

(3)

Synaptotagmin-4

(3)

Synaptotagmin-7

(3)

SytIV

(3)

SytVII

(3)

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase

(2)

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

(2)

Axin interaction partner and dorsalization antagonist

(2)

Axin interactor, dorsalization-associated protein

(2)

C2 domain protein

(2)

C2 domain-containing protein

(2)

Doc2-beta

(2)

Double C2-like domain-containing protein beta

(2)

Dysferlin

(2)

Dystrophy-associated fer-1-like protein

(2)

E3 ubiquitin-protein ligase NEDD4

(2)

 

More...

Molecule type  (1)

Protein

(307)

Gene names  (133)

PIK3CG

(96)

Pik3cd

(24)

Syt1

(21)

PIK3CA

(19)

BRR2

(12)

SVP65

(12)

SYT

(12)

SYT1

(12)

Rph3a

(11)

Plcd1

(10)

Pkca

(7)

Prkca

(7)

RSS1

(7)

SNU246

(7)

SYGP-ORF66

(7)

YER172C

(7)

ASCC3L1

(5)

HELIC2

(5)

KIAA0788

(5)

KIAA0869

(5)

KIBRA

(5)

Pfp

(5)

Prf1

(5)

SNRNP200

(5)

WWC1

(5)

CPLA2

(4)

ESYT2

(4)

FAM62B

(4)

KIAA1228

(4)

PLA2G4

(4)

PLA2G4A

(4)

PLCB3

(4)

Unc13a

(4)

Unc13h1

(4)

CCDC100

(3)

CEP120

(3)

PIK3C2A

(3)

C2P1

(2)

DYSF

(2)

Doc2b

(2)

FER1L1

(2)

FER1L3

(2)

KIAA1207

(2)

MYOF

(2)

PLCB2

(2)

Pik3cb

(2)

Pkcb

(2)

Prkcb

(2)

Prkcb1

(2)

SYT5

(2)

Syt3

(2)

Syt4

(2)

Syt7

(2)

Aida

(1)

At1g63220

(1)

CTHT_0009470

(1)

Cpk

(1)

DOC2A

(1)

DOCK1

(1)

F9N12.16

(1)

FTM

(1)

Fer1l2

(1)

GRB1

(1)

ITCH

(1)

ITSN2

(1)

KIAA0093

(1)

KIAA0439

(1)

KIAA0751

(1)

KIAA1005

(1)

KIAA1256

(1)

KIAA1342

(1)

KIAA1427

(1)

KIAA1625

(1)

Kiaa0093

(1)

MCTP2

(1)

NEDD4

(1)

NEDD4-1

(1)

NEDD4L

(1)

NEDL3

(1)

NPHP8

(1)

Nedd-4

(1)

Nedd4

(1)

Nedd4-1

(1)

Nedd4a

(1)

Otof

(1)

PCANAP7

(1)

PIG53

(1)

PIK3CD

(1)

PIK3R1

(1)

PKCA

(1)

PKCD

(1)

PKCG

(1)

PKCL

(1)

PP16-2

(1)

PRKACA

(1)

PRKCA

(1)

PRKCD

(1)

PRKCG

(1)

PRKCH

(1)

PRKCL

(1)

 

More...

Interacting Molecules  (77)

Phosphatidylinositol 3-kinase regulatory subunit alpha

(15)

Synaptosomal-associated protein 25

(8)

Pre-mRNA-splicing factor 8

(6)

Syntaxin-1A

(6)

Vesicle-associated membrane protein 2

(5)

Guanine nucleotide-binding protein G(q) subunit alpha

(4)

Small nuclear ribonucleoprotein E

(4)

Small nuclear ribonucleoprotein F

(4)

Small nuclear ribonucleoprotein G

(4)

Small nuclear ribonucleoprotein Sm D1

(4)

Small nuclear ribonucleoprotein Sm D2

(4)

Small nuclear ribonucleoprotein Sm D3

(4)

Small nuclear ribonucleoprotein-associated protein B

(4)

Pre-mRNA-splicing factor SNU114

(3)

13 kDa ribonucleoprotein-associated protein

(2)

66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

(2)

Complexin-1

(2)

Fibroblast growth factor 1

(2)

Pre-mRNA-processing factor 31

(2)

Pre-mRNA-splicing factor 6

(2)

Protein S100-A13

(2)

Spliceosomal protein DIB1

(2)

U4/U6 small nuclear ribonucleoprotein PRP3

(2)

U4/U6 small nuclear ribonucleoprotein PRP4

(2)

U6 snRNA-associated Sm-like protein LSm2

(2)

U6 snRNA-associated Sm-like protein LSm3

(2)

U6 snRNA-associated Sm-like protein LSm4

(2)

U6 snRNA-associated Sm-like protein LSm5

(2)

U6 snRNA-associated Sm-like protein LSm6

(2)

U6 snRNA-associated Sm-like protein LSm7

(2)

U6 snRNA-associated Sm-like protein LSm8

(2)

13-residue peptide

(1)

CWC15

(1)

CWC22

(1)

Exon 1 (5' exon) of UBC4 pre-mRNA

(1)

GTPase HRas, N-terminally processed

(1)

Growth factor receptor-bound protein 10

(1)

Intron of UBC4 pre-mRNA

(1)

MPN domain-containing protein

(1)

Phosphatidylinositol 3-kinase regulatory subunit beta

(1)

Pre-mRNA-processing factor 19

(1)

Pre-mRNA-processing protein 45

(1)

Pre-mRNA-processing-splicing factor 8

(1)

Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

(1)

Pre-mRNA-splicing factor BUD31

(1)

Pre-mRNA-splicing factor CEF1

(1)

Pre-mRNA-splicing factor CLF1

(1)

Pre-mRNA-splicing factor CWC2

(1)

Pre-mRNA-splicing factor CWC21

(1)

Pre-mRNA-splicing factor CWC25

(1)

Pre-mRNA-splicing factor ISY1

(1)

Pre-mRNA-splicing factor PRP46

(1)

Pre-mRNA-splicing factor SLT11

(1)

Pre-mRNA-splicing factor SNT309

(1)

Pre-mRNA-splicing factor SYF1

(1)

Protein kinase C alpha type

(1)

Ras-related C3 botulinum toxin substrate 1

(1)

Regulating synaptic membrane exocytosis protein 2

(1)

SNR14 snRNA

(1)

SNR6 snRNA

(1)

SNR7-L snRNA

(1)

Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence

(1)

Splicing factor YJU2

(1)

Synaptic vesicle glycoprotein 2A

(1)

U2 small nuclear ribonucleoprotein A'

(1)

U2 small nuclear ribonucleoprotein B''

(1)

U2 snRNA (small nuclear RNA)

(1)

U4 snRNA

(1)

U5 snRNA

(1)

U5 snRNA (small nuclear RNA)

(1)

U6 snRNA

(1)

U6 snRNA (small nuclear RNA)

(1)

Unknown protein

(1)

Vesicle-associated membrane protein 3

(1)

X-linked retinitis pigmentosa GTPase regulator

(1)

pre-mRNA

(1)

unknown

(1)

Interacting ligands  (178)

SO4 : SULFATE ION

(64)

CA : CALCIUM ION

(58)

GOL : GLYCEROL

(28)

ACT : ACETATE ION

(14)

CL : CHLORIDE ION

(11)

NA : SODIUM ION

(7)

EDO : 1,2-ETHANEDIOL

(6)

MG : MAGNESIUM ION

(6)

CD : CADMIUM ION

(4)

I3P : D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE

(4)

PB : LEAD (II) ION

(4)

PO4 : PHOSPHATE ION

(4)

ADP : ADENOSINE-5'-DIPHOSPHATE

(3)

FMT : FORMIC ACID

(3)

GD9 : 2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine

(3)

O4B : 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE

(3)

039 : 2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE

(2)

5H5 : (2S)-2-({2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}oxy)propanamide

(2)

ATP : ADENOSINE-5'-TRIPHOSPHATE

(2)

BME : BETA-MERCAPTOETHANOL

(2)

FLC : CITRATE ANION

(2)

IHP : INOSITOL HEXAKISPHOSPHATE

(2)

IOD : IODIDE ION

(2)

J82 : 2-[2-(2-METHYL-2,3-DIHYDRO-INDOL-1-YL)-2-OXO-ETHYL]-6-MORPHOLIN-4-YL-3H-PYRIMIDIN-4-ONE

(2)

KWT : (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE

(2)

ML9 : 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one

(2)

PIO : [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate

(2)

SAN : SULFANILAMIDE

(2)

SCN : THIOCYANATE ION

(2)

SR : STRONTIUM ION

(2)

ZN : ZINC ION

(2)

090 : N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDE

(1)

093 : N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE

(1)

0KO : 4-(2-[(6-methoxypyridin-3-yl)amino]-5-{[4-(methylsulfonyl)piperazin-1-yl]methyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine

(1)

0SC : 2-(1-{[2-(5-fluoro-1H-indol-4-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol

(1)

0SD : 2-(1-{[2-(2H-indazol-4-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol

(1)

0SE : 2-(1-{[2-(2-aminopyrimidin-5-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol

(1)

0TA : 2-amino-8-cyclopentyl-4-methyl-6-(1H-pyrazol-4-yl)pyrido[2,3-d]pyrimidin-7(8H)-one

(1)

0TB : 2-amino-6-(5-fluoro-6-methoxypyridin-3-yl)-4-methyl-8-(pyrrolidin-1-yl)pyrido[2,3-d]pyrimidin-7(8H)-one

(1)

0TZ : 3-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-pyrazol-5-yl)imidazo[1,2-a]pyridin-2-amine

(1)

0U0 : 3-[2-methyl-6-(pyrazin-2-ylamino)pyrimidin-4-yl]-N-(1H-pyrazol-3-yl)imidazo[1,2-b]pyridazin-2-amine

(1)

0VU : 4-({4-[3-(piperidin-1-ylcarbonyl)phenyl]pyrimidin-2-yl}amino)benzenesulfonamide

(1)

0W7 : 2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]-N-phenylacetamide

(1)

0WR : 2-[1-({2-[2-(dimethylamino)-1H-benzimidazol-1-yl]-9-methyl-6-(morpholin-4-yl)-9H-purin-8-yl}methyl)piperidin-4-yl]propan-2-ol

(1)

13K : N~6~-(3,4-dimethoxyphenyl)-2-(morpholin-4-yl)-4,5'-bipyrimidine-2',6-diamine

(1)

14K : 4-(2-[(5-fluoro-6-methoxypyridin-3-yl)amino]-5-{(1R)-1-[4-(methylsulfonyl)piperazin-1-yl]ethyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine

(1)

17V : 2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-4,5-dihydrothieno[3,2-d][1]benzoxepine-8-carboxamide

(1)

19P : 1-{1-[(2S)-2-hydroxypropanoyl]piperidin-4-yl}-3-methyl-8-(6-methylpyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c][1,5]naphthyridin-2-one

(1)

1JV : 2-methyl-1-(4-{2-[1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl]-4,5-dihydro[1]benzoxepino[5,4-d][1,3]thiazol-8-yl}-1H-pyrazol-1-yl)propan-2-ol

(1)

1LT : (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide

(1)

1UJ : methyl 2-(acetylamino)-1,3-benzothiazole-6-carboxylate

(1)

1UK : N-{6-[6-amino-5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-a]pyridin-2-yl}acetamide

(1)

2NQ : N-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide

(1)

2WH : 1-[6-(5-methoxypyridin-3-yl)-1,3-benzothiazol-2-yl]-3-[2-(1-propyl-1H-imidazol-4-yl)ethyl]urea

(1)

2WJ : N-[6-(pyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide

(1)

2WK : N-[6-(5,6-dimethoxypyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide

(1)

3K6 : N,N-dimethyl-4-[(6R)-6-methyl-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-yl]benzenesulfonamide

(1)

3PS : 4-amino-N-(6-methoxypyridin-3-yl)-2-methylquinazoline-8-carboxamide

(1)

3QH : 6-cyano-4-[[(1R)-1-(4-methylphenyl)ethyl]amino]quinoline-3-carboxamide

(1)

3RE : 2-amino-8-(trans-4-methoxycyclohexyl)-4-methyl-6-(1H-pyrazol-3-yl)pyrido[2,3-d]pyrimidin-7(8H)-one

(1)

3RZ : 4-amino-2-methyl-N-(1H-pyrazol-3-yl)quinazoline-8-carboxamide

(1)

3T8 : N~2~-{2-chloro-4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-N~2~,N~8~-dimethyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2,8-dicarboxamide

(1)

3VC : N-{(1S)-1-[7-fluoro-2-(pyridin-2-yl)quinolin-3-yl]ethyl}-9H-purin-6-amine

(1)

3VD : N-{(1S)-1-[8-chloro-2-(3-fluorophenyl)quinolin-3-yl]ethyl}-9H-purin-6-amine

(1)

3VE : N-{(1S)-1-[8-chloro-2-(2-methylpyridin-3-yl)quinolin-3-yl]ethyl}-9H-purin-6-amine

(1)

40L : 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4(3H)-one

(1)

41A : 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one

(1)

43R : N-[5-(5-methoxypyridin-3-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]acetamide

(1)

456 : N-[5-(6-methoxypyrazin-2-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]acetamide

(1)

4EL : 3-(6-methoxypyridin-3-yl)-5-[({4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}amino)methyl]benzoic acid

(1)

4FJ : 1'-[7-fluoro-3-methyl-2-(pyridin-2-yl)quinolin-4-yl]-6'-(morpholin-4-yl)-1',2,2',3,5,6-hexahydrospiro[pyran-4,3'-pyrrolo[3,2-b]pyridine]

(1)

4PT : (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE

(1)

4Q2 : (2S,3R)-N~1~-(8-tert-butyl-4,5-dihydro[1,3]thiazolo[4,5-h]quinazolin-2-yl)-3-methylpyrrolidine-1,2-dicarboxamide

(1)

534 : 5-{3-[(4-{3-[4-(1-methylethyl)phenyl]pyrazin-2-yl}piperazin-1-yl)sulfonyl]phenyl}pyrimidin-2-amine

(1)

5H2 : methyl {2-[4-(2-chlorophenyl)-4H-1,2,4-triazol-3-yl]-4,5-dihydrothieno[3,2-d][1]benzoxepin-8-yl}carbamate

(1)

5MT : 4-azanyl-6-[[(1~{S})-1-[6-fluoranyl-1-(3-methylsulfonylphenyl)benzimidazol-2-yl]ethyl]amino]pyrimidine-5-carbonitrile

(1)

5XV : ~{N}-[6-[5-azanyl-6-[(2~{S})-1,1,1-tris(fluoranyl)propan-2-yl]oxy-pyrazin-2-yl]imidazo[1,2-a]pyridin-2-yl]ethanamide

(1)

6CY : 5-{4-[3-(4-acetylpiperazine-1-carbonyl)phenyl]quinazolin-6-yl}-2-methoxypyridine-3-carbonitrile

(1)

6E2 : 2-azanyl-~{N}-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide

(1)

6K5 : [1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol

(1)

6K7 : [1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)pyrimidin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol

(1)

6RF : 4-azanyl-6-[[(1~{S})-1-(6-fluoranyl-3-phenyl-4-piperazin-1-ylcarbonyl-quinolin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile

(1)

74F : 3-(benzotriazol-1-yl)-5-[1-methyl-5-[(1~{S})-1-morpholin-4-ylethyl]-1,2,4-triazol-3-yl]pyrazin-2-amine

(1)

751 : 2-{4-[(4'-METHOXYBIPHENYL-3-YL)SULFONYL]PIPERAZIN-1-YL}-3-(4-METHOXYPHENYL)PYRAZINE

(1)

76C : 2,4-bis(azanyl)-6-[[(1~{S})-1-[5-chloranyl-3-(5-fluoranyl-4-methyl-pyridin-3-yl)-4-oxidanylidene-quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile

(1)

77C : 2,4-diamino-6-{[(S)-[5-chloro-8-fluoro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl](cyclopropyl)methyl]amino}pyrimidine-5-carbonitrile

(1)

7L0 : N-[6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]ethanamide

(1)

8TN : 4-azanyl-6-[[(1~{S})-1-[6-[3-[(dimethylamino)methyl]phenyl]-3-methyl-5-oxidanylidene-[1,3]thiazolo[3,2-a]pyridin-7-yl]ethyl]amino]pyrimidine-5-carbonitrile

(1)

8WH : 3-[[4-(2-morpholin-4-yl-4-oxidanylidene-3~{H}-quinolin-8-yl)-1,2,3-triazol-1-yl]methyl]benzoic acid

(1)

980 : (2S)-1-(4-{[2-(2-aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}piperazin-1-yl)-2-hydroxypropan-1-one

(1)

A3W : 5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine

(1)

A82 : 2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid

(1)

ABJ : 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL

(1)

ACY : ACETIC ACID

(1)

ANP : PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER

(1)

B3P : 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL

(1)

BA : BARIUM ION

(1)

BMW : 3-[7-(1H-benzimidazol-5-yl)-2-(morpholin-4-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]phenol

(1)

BWY : 10-[(S)-(1-tert-butylpiperidin-4-yl)sulfinyl]-2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine

(1)

BYM : (5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE

(1)

 

More...

EC number / name  (12)

2.7.1.153 : Phosphatidylinositol-4,5-bisphosphate 3-kinase

(147)

2.7.1.137 : Phosphatidylinositol 3-kinase

(145)

2.7.11.1 : Non-specific serine/threonine protein kinase

(118)

2.7.1.154 : Phosphatidylinositol-4-phosphate 3-kinase

(100)

3.1.4.11 : Phosphoinositide phospholipase C

(18)

2.7.11.13 : Protein kinase C

(16)

3.6.4.13 : RNA helicase

(12)

2.3.2.26 : HECT-type E3 ubiquitin transferase

(6)

3.1.1.4 : Phospholipase A(2)

(4)

3.1.1.5 : Lysophospholipase

(4)

2.3.2.36 : RING-type E3 ubiquitin transferase (cysteine targeting)

(1)

2.7.10.2 : Non-specific protein-tyrosine kinase

(1)

Biological function  (56)

kinase activity

(143)

1-phosphatidylinositol-3-kinase activity

(43)

ATP binding

(32)

nucleotide binding

(26)

protein binding

(25)

transferase activity

(21)

1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity

(20)

calcium ion binding

(18)

phosphatidylinositol-4,5-bisphosphate phospholipase C activity

(18)

phosphoric diester hydrolase activity

(18)

protein serine kinase activity

(18)

insulin receptor substrate binding

(17)

protein serine/threonine kinase activity

(17)

1-phosphatidylinositol-4-phosphate 3-kinase activity

(16)

protein kinase activator activity

(16)

nucleic acid binding

(11)

hydrolase activity

(7)

ATP hydrolysis activity

(6)

identical protein binding

(6)

RNA helicase activity

(5)

helicase activity

(5)

lipid binding

(5)

metal ion binding

(5)

diacylglycerol binding

(4)

small GTPase binding

(4)

calcium-dependent phospholipid binding

(3)

phospholipase C activity

(3)

phospholipid binding

(3)

wide pore channel activity

(3)

guanyl-nucleotide exchange factor activity

(2)

O-acyltransferase activity

(1)

cadherin binding

(1)

calcium channel regulator activity

(1)

calcium,diacylglycerol-dependent serine/threonine kinase activity

(1)

calcium-dependent phospholipase A2 activity

(1)

calcium-independent phospholipase A2 activity

(1)

calmodulin binding

(1)

ceramide 1-phosphate binding

(1)

chromatin binding

(1)

diacylglycerol-dependent serine/threonine kinase activity

(1)

histone H3T6 kinase activity

(1)

histone binding

(1)

lysophospholipase activity

(1)

molecular adaptor activity

(1)

molecular function activator activity

(1)

nuclear androgen receptor binding

(1)

phosphatidylinositol-3-phosphate binding

(1)

phosphatidylinositol-4-phosphate binding

(1)

phosphatidylinositol-5-phosphate binding

(1)

phospholipase A2 activity

(1)

phospholipase activity

(1)

pore-forming activity

(1)

protein kinase C binding

(1)

protein kinase activity

(1)

transcription coactivator activity

(1)

zinc ion binding

(1)

Biological process  (192)

phosphatidylinositol phosphate biosynthetic process

(142)

phosphatidylinositol 3-kinase/protein kinase B signal transduction

(43)

lipid metabolic process

(38)

phosphatidylinositol-3-phosphate biosynthetic process

(20)

intracellular signal transduction

(19)

signal transduction

(19)

phosphatidylinositol-mediated signaling

(17)

vascular endothelial growth factor signaling pathway

(17)

T cell receptor signaling pathway

(16)

actin cytoskeleton organization

(16)

adipose tissue development

(16)

angiogenesis

(16)

autosome genomic imprinting

(16)

cardiac muscle cell contraction

(16)

cell migration

(16)

cellular response to glucose stimulus

(16)

cellular response to hydrostatic pressure

(16)

cellular response to insulin stimulus

(16)

energy homeostasis

(16)

glucose metabolic process

(16)

insulin receptor signaling pathway

(16)

insulin-like growth factor receptor signaling pathway

(16)

liver development

(16)

negative regulation of actin filament depolymerization

(16)

negative regulation of anoikis

(16)

negative regulation of fibroblast apoptotic process

(16)

negative regulation of gene expression

(16)

negative regulation of neuron apoptotic process

(16)

phagocytosis

(16)

platelet activation

(16)

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

(16)

positive regulation of protein localization to membrane

(16)

positive regulation of smooth muscle cell proliferation

(16)

regulation of actin filament organization

(16)

regulation of cellular respiration

(16)

regulation of gene expression

(16)

regulation of multicellular organism growth

(16)

relaxation of cardiac muscle

(16)

response to L-leucine

(16)

response to activity

(16)

response to butyrate

(16)

response to dexamethasone

(16)

response to muscle inactivity

(16)

response to muscle stretch

(16)

anoikis

(15)

cardiac muscle contraction

(15)

endothelial cell migration

(15)

epidermal growth factor receptor signaling pathway

(15)

negative regulation of macroautophagy

(15)

positive regulation of TOR signaling

(15)

positive regulation of lamellipodium assembly

(15)

vasculature development

(15)

RNA splicing

(5)

mRNA processing

(5)

mRNA splicing, via spliceosome

(5)

spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)

(5)

B cell activation

(4)

adaptive immune response

(4)

chemical synaptic transmission

(4)

endoplasmic reticulum-plasma membrane tethering

(4)

exocytosis

(4)

immune system process

(4)

lipid transport

(4)

positive regulation of angiogenesis

(4)

positive regulation of gene expression

(4)

T cell mediated cytotoxicity

(3)

cell differentiation

(3)

chemotaxis

(3)

defense response to virus

(3)

immunological synapse formation

(3)

inflammatory response

(3)

innate immune response

(3)

B cell homeostasis

(2)

B cell receptor signaling pathway

(2)

cell surface receptor signaling pathway

(2)

defense response to fungus

(2)

homeostasis of number of cells

(2)

intracellular calcium ion homeostasis

(2)

lipid catabolic process

(2)

positive regulation of endothelial cell migration

(2)

positive regulation of neutrophil apoptotic process

(2)

protein phosphorylation

(2)

transmembrane transport

(2)

B cell chemotaxis

(1)

B cell differentiation

(1)

G protein-coupled receptor signaling pathway

(1)

T cell activation

(1)

T cell chemotaxis

(1)

T cell costimulation

(1)

T cell differentiation

(1)

TORC2 signaling

(1)

angiogenesis involved in wound healing

(1)

apoptotic process

(1)

arachidonate metabolic process

(1)

arachidonate secretion

(1)

autophagy

(1)

calcium ion transport

(1)

cell adhesion

(1)

cellular response to antibiotic

(1)

cellular response to carbohydrate stimulus

(1)

 

More...

Biological cell component  (39)

membrane

(68)

cytosol

(24)

cytoplasm

(22)

phosphatidylinositol 3-kinase complex, class IA

(18)

plasma membrane

(18)

phosphatidylinositol 3-kinase complex

(17)

intercalated disc

(16)

lamellipodium

(16)

perinuclear region of cytoplasm

(15)

phosphatidylinositol 3-kinase complex, class IB

(15)

nucleus

(9)

Prp19 complex

(5)

U4/U6 x U5 tri-snRNP complex

(5)

U5 snRNP

(5)

spliceosomal complex

(5)

intracellular membrane-bounded organelle

(2)

Golgi apparatus

(1)

Golgi membrane

(1)

brush border membrane

(1)

calyx of Held

(1)

centrosome

(1)

cytolytic granule

(1)

cytoplasmic vesicle

(1)

endoplasmic reticulum

(1)

endoplasmic reticulum membrane

(1)

endosome

(1)

endosome lumen

(1)

extracellular region

(1)

immunological synapse

(1)

lysosome

(1)

midbody

(1)

mitochondrial inner membrane

(1)

nuclear envelope

(1)

nucleolus

(1)

nucleoplasm

(1)

postsynaptic cytosol

(1)

presynaptic cytosol

(1)

protein-containing complex

(1)

spectrin

(1)

SCOP fold  (10)

C2 domain-like

(52)

EF Hand-like

(12)

TIM beta/alpha-barrel

(12)

Protein kinase-like (PK-like)

(8)

alpha-alpha superhelix

(8)

beta-Grasp (ubiquitin-like)

(8)

PH domain-like barrel

(2)

FabD/lysophospholipase-like

(1)

Immunoglobulin-like beta-sandwich

(1)

Sec63 N-terminal domain-like

(1)

SCOP family  (11)

PLC-like (P variant)

(30)

Synaptotagmin-like (S variant)

(22)

EF-hand modules in multidomain proteins

(12)

Mammalian PLC

(12)

Phoshoinositide 3-kinase (PI3K) helical domain

(8)

Phoshoinositide 3-kinase (PI3K), catalytic domain

(8)

Ras-binding domain, RBD

(8)

Pleckstrin-homology domain (PH domain)

(2)

Lysophospholipase

(1)

Sec63 C-terminal domain-like

(1)

Sec63 N-terminal domain

(1)

CATH class  (3)

Mainly Beta

(307)

Alpha Beta

(173)

Mainly Alpha

(172)

CATH topology  (16)

Immunoglobulin-like

(307)

Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5

(142)

Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4

(142)

Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

(142)

Ubiquitin-like (UB roll)

(142)

TIM Barrel

(18)

Recoverin; domain 1

(16)

DNA polymerase; domain 1

(13)

Sec63 N-terminal domain-like fold

(13)

Arc Repressor Mutant, subunit A

(11)

Rossmann fold

(11)

PH-domain like

(6)

Cytosolic phospholipase A2 catalytic domain

(1)

Helix Hairpins

(1)

Phosphorylase Kinase; domain 1

(1)

Transferase(Phosphotransferase); domain 1

(1)

Pfam accession / name  (32)

PF00792 : PI3K_C2

(143)

PF00454 : PI3_PI4_kinase

(142)

PF00613 : PI3Ka

(142)

PF00794 : PI3K_rbd

(142)

PF00168 : C2

(139)

PF02192 : PI3K_p85B

(19)

PF00387 : PI-PLC-Y

(18)

PF00388 : PI-PLC-X

(18)

PF02889 : Sec63

(13)

PF00270 : DEAD

(11)

PF00271 : Helicase_C

(11)

PF09279 : EF-hand_like

(10)

PF17787 : PH_14

(8)

PF22631 : PLCB1-4-like_EFh

(8)

PF18149 : Helicase_PWI

(5)

PF21188 : BRR2_plug

(5)

PF21494 : PKC_C2

(3)

PF14186 : Aida_C2

(2)

PF00017 : SH2

(1)

PF00069 : Pkinase

(1)

PF00130 : C1_1

(1)

PF00433 : Pkinase_C

(1)

PF00621 : RhoGEF

(1)

PF01735 : PLA2_B

(1)

PF01823 : MACPF

(1)

PF08703 : PLC-beta_C

(1)

PF11618 : C2-C2_1

(1)

PF14429 : DOCK-C2

(1)

PF16454 : PI3K_P85_iSH2

(1)

PF16652 : PH_13

(1)

PF17047 : SMP_LBD

(1)

PF18111 : RPGR1_C

(1)

Diffraction protocol  (2)

Single wavelength

(262)

MAD

(5)

Diffraction radiation source type  (3)

Synchrotron

(243)

Rotating anode

(32)

Free-electron laser

(2)

Diffraction source  (73)

ALS BEAMLINE 5.0.2

(30)

ALS BEAMLINE 5.0.1

(16)

ESRF BEAMLINE ID14-4

(14)

RIGAKU MICROMAX-007 HF

(14)

APS BEAMLINE 19-BM

(10)

ESRF BEAMLINE ID29

(10)

ESRF BEAMLINE ID14-2

(9)

SLS BEAMLINE X06SA

(9)

APS BEAMLINE 19-ID

(8)

APS BEAMLINE 31-ID

(8)

AUSTRALIAN SYNCHROTRON BEAMLINE MX2

(8)

APS BEAMLINE 21-ID-F

(6)

APS BEAMLINE 24-ID-C

(6)

ESRF BEAMLINE ID14-1

(6)

ESRF BEAMLINE ID2

(6)

RIGAKU

(6)

SSRL BEAMLINE BL7-1

(6)

APS BEAMLINE 17-ID

(4)

APS BEAMLINE 22-ID

(4)

DIAMOND BEAMLINE I02

(4)

ESRF BEAMLINE ID23-1

(4)

SLS BEAMLINE X10SA

(4)

SSRF BEAMLINE BL17U

(4)

APS BEAMLINE 14-BM-C

(3)

APS BEAMLINE 21-ID-D

(3)

APS BEAMLINE 22-BM

(3)

BESSY BEAMLINE 14.2

(3)

CHESS BEAMLINE F1

(3)

DIAMOND BEAMLINE I04

(3)

RIGAKU FR-E SUPERBRIGHT

(3)

RIGAKU MICROMAX-007

(3)

SPRING-8 BEAMLINE BL41XU

(3)

SRS BEAMLINE PX9.6

(3)

SSRL BEAMLINE BL9-2

(3)

ALBA BEAMLINE XALOC

(2)

APS BEAMLINE 23-ID-D

(2)

CLSI BEAMLINE 08ID-1

(2)

EMBL/DESY, HAMBURG BEAMLINE BW7B

(2)

ESRF BEAMLINE ID23-2

(2)

NSLS BEAMLINE X25

(2)

NSLS BEAMLINE X29A

(2)

RIGAKU RUH2R

(2)

SLAC LCLS BEAMLINE XPP

(2)

SLS BEAMLINE X06DA

(2)

SOLEIL BEAMLINE PROXIMA 1

(2)

SSRL BEAMLINE BL11-1

(2)

ALS BEAMLINE 8.2.2

(1)

APS BEAMLINE 21-ID-G

(1)

APS BEAMLINE 23-ID-B

(1)

AUSTRALIAN SYNCHROTRON BEAMLINE MX1

(1)

BRUKER ROTATING ANODE

(1)

CAMD BEAMLINE GCPCC

(1)

CHESS BEAMLINE A1

(1)

Cu FINE FOCUS

(1)

DIAMOND BEAMLINE I03

(1)

DIAMOND BEAMLINE I04-1

(1)

EMBL/DESY, HAMBURG BEAMLINE X13

(1)

ESRF

(1)

ESRF BEAMLINE ID14-3

(1)

MPG/DESY, HAMBURG BEAMLINE BW6

(1)

NSLS BEAMLINE X12C

(1)

NSLS BEAMLINE X4A

(1)

NSLS BEAMLINE X6A

(1)

PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)

(1)

PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)

(1)

PHOTON FACTORY BEAMLINE AR-NW12A

(1)

PHOTON FACTORY BEAMLINE BL-5A

(1)

PHOTON FACTORY BEAMLINE BL-6A

(1)

RIGAKU FR-E

(1)

RIGAKU R-AXIS

(1)

SPRING-8 BEAMLINE BL26B2

(1)

SRS BEAMLINE PX14.2

(1)

SSRL BEAMLINE BL1-5

(1)

Synchrotron site  (22)

APS

(58)

ESRF

(53)

ALS

(47)

SLS

(15)

SSRL

(12)

Australian Synchrotron

(9)

Diamond

(9)

NSLS

(7)

CHESS

(4)

SPring-8

(4)

SRS

(4)

SSRF

(4)

BESSY

(3)

EMBL/DESY, Hamburg

(3)

Photon Factory

(3)

ALBA

(2)

CLSI

(2)

PETRA III, EMBL c/o DESY

(2)

SLAC LCLS

(2)

SOLEIL

(2)

CAMD

(1)

MPG/DESY, HAMBURG

(1)

Diffraction detector type  (4)

CCD

(197)

Image plate

(35)

Pixel

(34)

Area detector

(1)

Refinement software  (10)

REFMAC

(125)

PHENIX

(80)

CNS

(32)

BUSTER

(29)

TNT

(10)

BUSTER-TNT

(8)

CNX

(6)

X-PLOR

(6)

SHELXL-97

(2)

XTALVIEW

(1)

EM microscope model  (2)

FEI TITAN KRIOS

(3)

FEI TITAN

(1)

EM detector name  (2)

GATAN K2 SUMMIT (4k x 4k)

(3)

GATAN K2 QUANTUM (4k x 4k)

(1)

NMR software packages  (26)

NMRPipe

(17)

NMRView

(15)

VNMR

(14)

CYANA

(13)

KUJIRA

(12)

ARIA

(8)

CNS

(7)

Sparky

(7)

TopSpin

(4)

HADDOCK

(2)

ALMOST

(1)

ARIA/CNS

(1)

CARA

(1)

CcpNmr Analysis

(1)

Discover

(1)

GROMACS

(1)

NAMD

(1)

NMRCHITECT

(1)

Numbat

(1)

PLUMED2

(1)

PSVS

(1)

TALOS

(1)

VnmrJ

(1)

X-PLOR

(1)

XEASY

(1)

Xplor-NIH

(1)

NMR Field Strength

400.0 - 500

(5)

500.0 - 600

(12)

600.0 - 700

(11)

700.0 - 800

(21)

800.0 - 900

(21)

900.0 - 1000

(8)

Representative Structures

100%

95%

90%

70%

50%

40%

30%