Entry status  (1)

REL

(72)

Experimental methods  (1)

X-ray diffraction

(72)

Authors  (143)

Gaboriaud C

(22)

Martin L

(22)

Thielens NM

(22)

Arlaud GJ

(19)

Doolittle RF

(19)

Garlatti V

(19)

Fujita T

(18)

Lacroix M

(17)

Belloy N

(13)

Endo Y

(13)

Fontecilla-Camps JC

(13)

Matsushita M

(13)

Lord ST

(12)

Pandi L

(12)

Gorkun OV

(9)

Everse SJ

(8)

Kostelansky MS

(8)

Spraggon G

(8)

Gout E

(7)

Betts L

(6)

Kollman JM

(6)

Barton WA

(5)

Chung DW

(5)

Cote HC

(5)

Côté HC

(5)

Davie EW

(5)

Nikolov DB

(5)

Pratt KP

(5)

Reiser JB

(5)

Stenkamp RE

(5)

Veerapandian L

(5)

Chen A

(4)

Dickerson SK

(4)

Lounes KC

(4)

Ping LF

(4)

Riley M

(4)

Yang Z

(4)

Bowley SR

(3)

Laffly E

(3)

Rajashankar KR

(3)

Teller DC

(3)

Thielens N

(3)

Trong IL

(3)

Tzvetkova-Robev D

(3)

Vassal-Stermann E

(3)

Yee VC

(3)

Bolliger-Stucki B

(2)

Burns I

(2)

Cote HCF

(2)

Dalton AC

(2)

Goldgur Y

(2)

Greenhough TJ

(2)

Holmskov U

(2)

Merenbloom BK

(2)

Moeller JB

(2)

Okumura N

(2)

Paterson JM

(2)

Schlosser A

(2)

Seegar TC

(2)

Seegar TCM

(2)

Shaw AJ

(2)

Shrive AK

(2)

Sorensen GL

(2)

Tzvetkova D

(2)

Yu X

(2)

Adams EJ

(1)

Alanen HI

(1)

Amoroso A

(1)

Applegate D

(1)

Arrowsmith CH

(1)

Beisel H-G

(1)

Beisel HG

(1)

Bezerra GA

(1)

Biterova E

(1)

Biterova EI

(1)

Bode W

(1)

Bountra C

(1)

Bradshaw WJ

(1)

Buffalo C

(1)

Burgess-Brown N

(1)

Burrows JM

(1)

Cesbron JY

(1)

Coker JA

(1)

Cole JN

(1)

Di Guilmi AM

(1)

Dumestre-Perard C

(1)

Dumestre-Pérard C

(1)

Esmaeeli M

(1)

Fernandez-Cid A

(1)

Fu CY

(1)

Fuentes-Prior P

(1)

Fuh G

(1)

Ghosh P

(1)

Gileadi O

(1)

Grieninger G

(1)

Harris SF

(1)

Heroux A

(1)

Himanen JP

(1)

Huber R

(1)

Iwanaga S

(1)

 

More...

Homo / hetero assembly  (2)

homo

(37)

hetero

(35)

Assembly composition  (2)

protein structure

(37)

protein/protein complex

(35)

Assembly polymer count  (9)

monomer

(19)

trimer

(19)

pentamer

(10)

decamer

(8)

tetramer

(7)

dimer

(4)

octamer

(3)

hexamer

(1)

tetradecamer

(1)

Resolution distribution

1.0 - 1.5

(2)

1.5 - 2

(11)

2.0 - 2.5

(26)

2.5 - 3

(28)

3.0 - 3.5

(3)

3.5 - 4

(2)

Release year distribution

1995 - 2000

(12)

2000 - 2005

(13)

2005 - 2010

(37)

2010 - 2015

(10)

2015 - 2020

(3)

Journal  (13)

Biochemistry

(23)

EMBO J

(13)

J Biol Chem

(10)

Proc Natl Acad Sci U S A

(6)

Structure

(5)

Nature

(3)

FEBS Lett

(2)

To be published

(2)

Blood

(1)

J Immunol

(1)

J Thromb Haemost

(1)

Nat Struct Mol Biol

(1)

Sci Rep

(1)

Organism superkingdom  (1)

Eukaryota

(72)

Organism name  (4)

Homo sapiens

(68)

Petromyzon marinus

(2)

Gallus gallus

(1)

Tachypleus tridentatus

(1)

Molecule name  (48)

Fibrinogen gamma chain

(36)

Fibrinogen beta chain

(30)

Fibrinopeptide B

(30)

37 kDa elastin-binding protein

(13)

Collagen/fibrinogen domain-containing protein 2

(13)

EBP-37

(13)

Ficolin-2

(13)

Ficolin-B

(13)

Ficolin-beta

(13)

Hucolin

(13)

L-ficolin

(13)

Serum lectin p35

(13)

Collagen/fibrinogen domain-containing protein 1

(7)

Ficolin-1

(7)

Ficolin-A

(7)

Ficolin-alpha

(7)

M-ficolin

(7)

ANG-2

(5)

Angiopoietin-2

(5)

Collagen/fibrinogen domain-containing lectin 3 p35

(3)

Collagen/fibrinogen domain-containing protein 3

(3)

Ficolin-3

(3)

Hakata antigen

(3)

ANG-1

(2)

Angiopoietin-1

(2)

Fibrinogen C domain-containing protein 1

(2)

ANGPTL4 C-terminal chain

(1)

ANGPTL4 N-terminal chain

(1)

Angiopoietin-like protein 4

(1)

Angiopoietin-related protein 4

(1)

Cytotactin

(1)

Fibrinogen C-terminal domain-containing protein

(1)

Fibrinogen alpha chain

(1)

Fibrinopeptide A

(1)

GMEM

(1)

GP 150-225

(1)

Glioma-associated-extracellular matrix antigen

(1)

HFARP

(1)

Hepatic fibrinogen/angiopoietin-related protein

(1)

Hexabrachion

(1)

JI

(1)

Myotendinous antigen

(1)

Neuronectin

(1)

TN

(1)

TN-C

(1)

Techylectin-5A

(1)

Tenascin

(1)

Tenascin-C

(1)

Molecule type  (1)

Protein

(72)

Gene names  (25)

FGG

(35)

PRO2061

(33)

FGB

(28)

FCN2

(13)

FCNL

(13)

FCN1

(7)

FCNM

(7)

ANGPT2

(5)

FCN3

(3)

FCNH

(3)

HAKA1

(3)

ANGPT1

(2)

FIBCD1

(2)

KIAA0003

(2)

UNQ701/PRO1346

(2)

ANGPTL4

(1)

ARP4

(1)

FGA

(1)

HFARP

(1)

HXB

(1)

PGAR

(1)

PP1158

(1)

PSEC0166

(1)

TNC

(1)

UNQ171/PRO197

(1)

Interacting Molecules  (33)

Fibrinogen beta chain

(31)

Fibrinogen alpha chain

(29)

Fibrinogen gamma chain

(29)

GHRP peptide

(3)

Fibrinogen alpha-1 chain

(2)

4-mer peptide GPRP

(1)

A knob

(1)

Angiopoietin-1 receptor

(1)

B knob

(1)

FIBRIN

(1)

Fibrin B Knob (GHRPam)

(1)

Fibrin B Knob (MHRPYam)

(1)

Fibrin B knob (tetrapeptide)

(1)

Fibrinogen C-terminal domain-containing protein

(1)

Ficolin-2

(1)

Fragment antigen binding 5A12 heavy chain

(1)

Fragment antigen binding 5A12 light chain

(1)

GLY-HIS-ARG-PRO peptide

(1)

GLY-HIS-ARG-PRO-AMIDE peptide ligand

(1)

GLY-HYP-ARG-PRO-AMIDE PEPTIDE LIGAND

(1)

GLY-PRO-ARG-PRO

(1)

GLY-PRO-ARG-PRO peptide

(1)

GLY-PRO-ARG-VAL-VAL-GLU peptide

(1)

GPRP Peptide

(1)

Gly-His-Arg-Pro

(1)

Gly-His-Arg-Pro-amide

(1)

Gly-Pro-Arg-Pro

(1)

Gly-Pro-Arg-Pro-amide peptide ligand

(1)

Gly-hydroxyPro-Arg-Pro-amide peptide ligand

(1)

M PROTEIN

(1)

PEPTIDE LIGAND GPRG

(1)

Peptide Ligand Gly-His-Arg-Pro-NH2

(1)

Peptide Ligand Gly-Pro-Arg-Pro-amide

(1)

Interacting ligands  (27)

CA : CALCIUM ION

(68)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(46)

FUC : alpha-L-fucopyranose

(12)

ACT : ACETATE ION

(9)

MAN : alpha-D-mannopyranose

(8)

BMA : beta-D-mannopyranose

(7)

NDG : 2-acetamido-2-deoxy-alpha-D-glucopyranose

(6)

SO4 : SULFATE ION

(5)

P4C : O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL

(4)

EPE : 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID

(3)

A2G : 2-acetamido-2-deoxy-alpha-D-galactopyranose

(2)

BM3 : 2-acetamido-2-deoxy-alpha-D-mannopyranose

(2)

GAL : beta-D-galactopyranose

(2)

IPA : ISOPROPYL ALCOHOL

(2)

SC2 : N-ACETYL-L-CYSTEINE

(2)

1PE : PENTAETHYLENE GLYCOL

(1)

3LJ : 2-amino-2-deoxy-6-O-sulfo-alpha-D-glucopyranose

(1)

ABE : alpha-D-Abequopyranose

(1)

ACH : ACETYLCHOLINE

(1)

ACY : ACETIC ACID

(1)

BGC : beta-D-glucopyranose

(1)

GLA : alpha-D-galactopyranose

(1)

GOL : GLYCEROL

(1)

PC : PHOSPHOCHOLINE

(1)

PO4 : PHOSPHATE ION

(1)

SIA : N-acetyl-alpha-neuraminic acid

(1)

SLB : N-acetyl-beta-neuraminic acid

(1)

Biological function  (9)

signaling receptor binding

(31)

metal ion binding

(3)

cell adhesion molecule binding

(2)

extracellular matrix structural constituent

(2)

protein binding

(2)

structural molecule activity

(2)

carbohydrate binding

(1)

protein-folding chaperone binding

(1)

protein-macromolecule adaptor activity

(1)

Biological process  (28)

blood coagulation

(45)

platelet activation

(31)

protein polymerization

(31)

blood coagulation, fibrin clot formation

(3)

cell-matrix adhesion

(3)

hemostasis

(3)

platelet aggregation

(3)

fibrinolysis

(2)

negative regulation of endothelial cell apoptotic process

(2)

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

(2)

plasminogen activation

(2)

positive regulation of ERK1 and ERK2 cascade

(2)

positive regulation of exocytosis

(2)

positive regulation of heterotypic cell-cell adhesion

(2)

positive regulation of peptide hormone secretion

(2)

positive regulation of protein secretion

(2)

positive regulation of substrate adhesion-dependent cell spreading

(2)

positive regulation of vasoconstriction

(2)

protein-containing complex assembly

(2)

response to calcium ion

(2)

adaptive immune response

(1)

cell-cell adhesion

(1)

cellular response to interleukin-1

(1)

cellular response to leptin stimulus

(1)

immune system process

(1)

induction of bacterial agglutination

(1)

innate immune response

(1)

protein secretion

(1)

Biological cell component  (16)

fibrinogen complex

(31)

extracellular region

(4)

extracellular space

(4)

collagen-containing extracellular matrix

(3)

blood microparticle

(2)

cell surface

(2)

external side of plasma membrane

(2)

extracellular exosome

(2)

plasma membrane

(2)

platelet alpha granule

(2)

platelet alpha granule lumen

(2)

cell cortex

(1)

endoplasmic reticulum

(1)

endoplasmic reticulum lumen

(1)

extracellular vesicle

(1)

synapse

(1)

SCOP fold  (2)

Fibrinogen C-terminal domain-like

(25)

Parallel coiled-coil

(19)

SCOP family  (2)

Fibrinogen C-terminal domain-like

(25)

Fibrinogen coiled-coil and central regions

(19)

CATH class  (3)

Alpha Beta

(72)

Few Secondary Structures

(72)

Mainly Alpha

(19)

CATH topology  (3)

Gamma Fibrinogen; Chain A, domain 1

(72)

Gamma-fibrinogen Carboxyl Terminal Fragment; domain 2

(72)

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

(19)

Representative Structures

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