Entry status  (1)

REL

(33)

Experimental methods  (1)

X-ray diffraction

(33)

Authors  (171)

Cherfils J

(9)

Hible G

(9)

Christova P

(7)

Renault L

(7)

Gilles AM

(5)

Girard E

(4)

Munier-Lehmann H

(4)

Seclaman E

(4)

Thompson A

(4)

Evrin C

(3)

Li Y

(3)

Prehoda KE

(3)

Radulescu AZ

(3)

Schaeffer F

(3)

Zoe Radulescu A

(3)

Blaszczyk J

(2)

Bochkarev A

(2)

Brunger AT

(2)

Chan S

(2)

Daalova P

(2)

Doe CQ

(2)

Ji X

(2)

Johnston CA

(2)

Konrad M

(2)

Lavie A

(2)

Panepucci EH

(2)

Perry LJ

(2)

Sawaya MR

(2)

Shang Y

(2)

Spangenberg O

(2)

Structural Genomics Consortium (SGC)

(2)

Tavares GA

(2)

Tempel W

(2)

Yan H

(2)

Zhang M

(2)

Zhu J

(2)

Abendroth J

(1)

Akiyama T

(1)

Alam Z

(1)

Amador-Noguez D

(1)

Amani M

(1)

Anderson WF

(1)

Arakawa A

(1)

Arrowsmith C

(1)

Arrowsmith CH

(1)

Artz J

(1)

Bountra C

(1)

Bray J

(1)

Bredt DS

(1)

Brokx S

(1)

Brunzelle JS

(1)

Burshteyn F

(1)

Carlier PR

(1)

Cassidy M

(1)

Center for Structural Genomics of Infectious Diseases (CSGID)

(1)

Charles I

(1)

Cheung J

(1)

Choe J

(1)

Choi B

(1)

Claas KR

(1)

Dakoji SR

(1)

Davies D

(1)

Dhaliwal B

(1)

Diassiti A

(1)

Dong A

(1)

Edwards A

(1)

Edwards AM

(1)

Eisenberg D

(1)

El Omari K

(1)

Feng G

(1)

Franklin M

(1)

Franklin MC

(1)

Gao M

(1)

Gary E

(1)

Guan X

(1)

Handa N

(1)

Hawkins AR

(1)

Hillerich B

(1)

Hills T

(1)

Houston S

(1)

Huang X

(1)

Hui R

(1)

Kain K

(1)

Ke X

(1)

Keck JL

(1)

Klock HE

(1)

Kozieradzki I

(1)

Krasny K

(1)

Kreusch A

(1)

Kwok J

(1)

Le Trong I

(1)

Lesley SA

(1)

Lew J

(1)

Li H

(1)

Li SSC

(1)

Lim WA

(1)

Liu K

(1)

Lockyer M

(1)

Loppnau P

(1)

Love J

(1)

 

More...

Homo / hetero assembly  (2)

homo

(30)

hetero

(3)

Assembly composition  (2)

protein structure

(30)

protein/protein complex

(3)

Assembly polymer count  (3)

monomer

(18)

dimer

(11)

hexamer

(4)

Resolution distribution

1.0 - 1.5

(1)

1.5 - 2

(11)

2.0 - 2.5

(17)

2.5 - 3

(2)

3.0 - 3.5

(2)

Release year distribution

1990 - 1995

(1)

2000 - 2005

(18)

2005 - 2010

(15)

2010 - 2015

(9)

2015 - 2020

(2)

Journal  (12)

To be published

(8)

J Mol Biol

(6)

Proteins

(5)

Mol Cell

(4)

Biochimie

(2)

J Biol Chem

(2)

Acta Crystallogr Sect F Struct Biol Cryst Commun

(1)

Biochem Biophys Res Commun

(1)

Cell Rep

(1)

EMBO J

(1)

Mol Biochem Parasitol

(1)

Proc Natl Acad Sci U S A

(1)

Organism superkingdom  (2)

Bacteria

(17)

Eukaryota

(16)

Organism name  (16)

Escherichia coli

(6)

Mycobacterium tuberculosis

(5)

Rattus norvegicus

(5)

Homo sapiens

(3)

Saccharomyces cerevisiae

(3)

Anaplasma phagocytophilum str. HZ

(1)

Coxiella burnetii

(1)

Drosophila melanogaster

(1)

Listeria monocytogenes

(1)

Mus musculus

(1)

Mycobacterium tuberculosis H37Rv

(1)

Plasmodium falciparum 3D7

(1)

Plasmodium vivax

(1)

Saccharomyces cerevisiae S288C

(1)

Staphylococcus aureus

(1)

Staphylococcus aureus USA300-ISMMS1

(1)

Molecule name  (25)

Guanylate kinase

(23)

GMP kinase

(22)

Disks large homolog 4

(4)

PSD-95

(4)

Postsynaptic density protein 95

(4)

SAP-90

(4)

SAP90

(4)

Synapse-associated protein 90

(4)

Disks large homolog 1

(2)

SAP-97

(2)

SAP97

(2)

Synapse-associated protein 97

(2)

guanylate kinase

(2)

55 kDa erythrocyte membrane protein

(1)

Calcium/calmodulin-dependent serine protein kinase

(1)

Disks large 1 tumor suppressor protein

(1)

Dlg

(1)

Guanylate kinase 1

(1)

Guanylate kinase, putative

(1)

Membrane protein, palmitoylated 1

(1)

Peripheral plasma membrane protein CASK

(1)

Protein lin-2 homolog

(1)

hCASK

(1)

hDlg

(1)

p55

(1)

Molecule type  (1)

Protein

(33)

Gene names  (32)

gmk

(17)

JW3623

(6)

MTCY21B4.06

(6)

Rv1389

(6)

b3648

(6)

spoR

(6)

D9461.39

(4)

Dlg4

(4)

Dlgh4

(4)

GUK1

(4)

Psd95

(4)

YDR454C

(4)

APH_0170

(1)

AZ30_05805

(1)

CASK

(1)

CBU_0301

(1)

CG1725

(1)

DLG1

(1)

DXS552E

(1)

Dlg1

(1)

Dlgh1

(1)

EMP55

(1)

Gmk

(1)

Guk1

(1)

LIN2

(1)

MPP1

(1)

PF3D7_0928900

(1)

PVX_099895

(1)

SACOL1221

(1)

dlg1

(1)

l(1)dlg1

(1)

lmo1827

(1)

Interacting Molecules  (3)

G-protein signaling modulator 2

(1)

RE22964p

(1)

Synthesized GK inhibitor

(1)

Interacting ligands  (18)

SO4 : SULFATE ION

(11)

5GP : GUANOSINE-5'-MONOPHOSPHATE

(10)

K : POTASSIUM ION

(4)

FMT : FORMIC ACID

(3)

GDP : GUANOSINE-5'-DIPHOSPHATE

(3)

0O2 : guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)

(1)

ADP : ADENOSINE-5'-DIPHOSPHATE

(1)

CL : CHLORIDE ION

(1)

EDO : 1,2-ETHANEDIOL

(1)

EPE : 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID

(1)

G5P : P1-(5'-ADENOSYL)-P5-(5'-GUANOSYL) PENTAPHOSPHATE

(1)

GAI : GUANIDINE

(1)

GMP : GUANOSINE

(1)

LGP : N9-1-HYDROXY-PROP-2-OXYMETHYL-GUANINE-3'-MONOPHOSPHATE

(1)

MPD : (4S)-2-METHYL-2,4-PENTANEDIOL

(1)

NA : SODIUM ION

(1)

PO4 : PHOSPHATE ION

(1)

POP : PYROPHOSPHATE 2-

(1)

EC number / name  (2)

2.7.4.8 : Guanylate kinase

(24)

2.7.11.1 : Non-specific serine/threonine protein kinase

(1)

Biological function  (10)

ATP binding

(24)

guanylate kinase activity

(24)

kinase activity

(24)

GDP binding

(6)

GMP binding

(6)

adenylate kinase activity

(6)

identical protein binding

(6)

magnesium ion binding

(6)

flavin adenine dinucleotide binding

(1)

oxidoreductase activity, acting on the CH-CH group of donors

(1)

Biological process  (8)

GMP metabolic process

(24)

purine nucleotide metabolic process

(24)

GDP metabolic process

(20)

nucleoside monophosphate phosphorylation

(6)

GDP biosynthetic process

(4)

dGDP biosynthetic process

(1)

obsolete dGDP phosphorylation

(1)

xenobiotic metabolic process

(1)

Biological cell component  (4)

cytosol

(24)

cytoplasm

(22)

nucleus

(4)

photoreceptor inner segment

(1)

SCOP fold  (2)

P-loop containing nucleoside triphosphate hydrolases

(19)

SH3-like barrel

(3)

SCOP family  (2)

Nucleotide and nucleoside kinases

(19)

SH3-domain

(3)

CATH class  (2)

Alpha Beta

(33)

Mainly Beta

(6)

CATH topology  (3)

Guanylate Kinase phosphate binding domain

(33)

Rossmann fold

(33)

SH3 type barrels.

(6)

Pfam accession / name  (2)

PF00625 : Guanylate_kin

(33)

PF00018 : SH3_1

(6)

Representative Structures

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