Entry status  (1)

REL

(26)

Experimental methods  (2)

X-ray diffraction

(25)

Solution NMR

(1)

Authors  (85)

Russell RJ

(9)

Hale BG

(8)

Kerry PS

(8)

Randall RE

(8)

Garcia-Sastre A

(7)

García-Sastre A

(7)

Russell RJM

(7)

Taylor MA

(7)

Ayllon J

(6)

Hass C

(6)

Lewis A

(6)

Bornholdt ZA

(4)

Prasad BV

(4)

Robertus JD

(4)

Xia S

(4)

Chen S

(3)

Hilgenfeld R

(3)

Xiao YB

(3)

Bricogne G

(2)

Carrillo B

(2)

Choi JM

(2)

Krug RM

(2)

Montelione GT

(2)

Monzingo AF

(2)

Northeast Structural Genomics Consortium (NESG)

(2)

Prasad BVV

(2)

Rice AP

(2)

Sankaran B

(2)

Sharff AJ

(2)

Xiao R

(2)

Zhao L

(2)

Aramini J

(1)

Aramini JM

(1)

Arnold E

(1)

Barclay WS

(1)

Center for Structural Genomics of Infectious Diseases (CSGID)

(1)

Ciccosanti C

(1)

Cunningham K

(1)

Cusack S

(1)

Das K

(1)

Esparza M

(1)

Falahat SM

(1)

Fang Y

(1)

Fontoura BMA

(1)

Fremont DH

(1)

Gray A

(1)

Green TJ

(1)

Haubrich K

(1)

Hennig J

(1)

Jackson D

(1)

Janjua H

(1)

Jureka AS

(1)

Killip MJ

(1)

Kleinpeter AB

(1)

Koliopoulos MG

(1)

Kowalinski E

(1)

Kuo RL

(1)

Lee H

(1)

Lethier M

(1)

Long E

(1)

Ma L

(1)

Ma L-C

(1)

Ma LC

(1)

Marklund J

(1)

Martin SR

(1)

Munoz-Moreno R

(1)

Muñoz-Moreno R

(1)

Nelson CA

(1)

Petit CM

(1)

Ponnusamy R

(1)

Precious BL

(1)

Radvansky B

(1)

Reis E Sousa C

(1)

Reis e Sousa C

(1)

Ren Y

(1)

Rittinger K

(1)

Sankaran S

(1)

Stevens RV

(1)

Twu KY

(1)

Wang J

(1)

Xie Y

(1)

Yu YYL

(1)

Zhang K

(1)

Zhang L

(1)

van der Veen AG

(1)

Homo / hetero assembly  (2)

homo

(22)

hetero

(4)

Assembly composition  (2)

protein structure

(22)

protein/protein complex

(4)

Assembly polymer count  (5)

dimer

(14)

monomer

(9)

octamer

(1)

tetramer

(1)

trimer

(1)

Resolution distribution

1.5 - 2

(6)

2.0 - 2.5

(9)

2.5 - 3

(6)

3.0 - 3.5

(3)

3.5 - 4

(1)

Release year distribution

2005 - 2010

(11)

2010 - 2015

(16)

2015 - 2020

(3)

Journal  (13)

PLoS One

(6)

To be published

(5)

Acta Crystallogr D Biol Crystallogr

(2)

Arch Biochem Biophys

(2)

J Virol

(2)

Proc Natl Acad Sci U S A

(2)

Acta Crystallogr Sect F Struct Biol Cryst Commun

(1)

J Biol Chem

(1)

Nat Commun

(1)

Nat Microbiol

(1)

Nat Struct Mol Biol

(1)

Nature

(1)

Virology

(1)

Organism superkingdom  (1)

Viruses

(26)

Organism name  (11)

Influenza A virus (A/reassortant/IVR108(Sydney/5/1995 x Puerto Rico/8/1934)(H3N2))

(5)

Influenza A virus (A/Udorn/307/1972(H3N2))

(4)

Influenza A virus (A/Puerto Rico/8/1934(H1N1))

(3)

Influenza A virus (A/environment/Viet Nam/1203/2004(H5N1))

(3)

Influenza A virus

(2)

Influenza A virus (A/blue-winged teal/MN/993/1980(H6N6))

(2)

Influenza A virus (A/duck/Alberta/60/1976(H12N5))

(2)

unidentified influenza virus

(2)

Influenza A virus (A/Brevig Mission/1/1918(H1N1))

(1)

Influenza A virus (A/California/07/2009(H1N1))

(1)

Influenza A virus (A/Hungary/2/1971(H3N2))

(1)

Molecule name  (5)

NS1

(26)

Non-structural protein 1

(26)

NS1A

(17)

Nonstructural protein 1

(6)

NS1 protein

(1)

Molecule type  (1)

Protein

(26)

Gene names  (2)

NS

(26)

NS1

(8)

Interacting Molecules  (6)

Cleavage and polyadenylation specificity factor subunit 4

(1)

E3 ubiquitin/ISG15 ligase TRIM25

(1)

NTF2-related export protein 1

(1)

Non-structural protein 1

(1)

Nuclear RNA export factor 1

(1)

Phosphatidylinositol 3-kinase regulatory subunit beta

(1)

Interacting ligands  (4)

SCN : THIOCYANATE ION

(2)

NO3 : NITRATE ION

(1)

P6G : HEXAETHYLENE GLYCOL

(1)

SO4 : SULFATE ION

(1)

Biological function  (4)

RNA binding

(26)

protein serine/threonine kinase inhibitor activity

(3)

protein binding

(2)

identical protein binding

(1)

Biological process  (6)

symbiont-mediated suppression of host PKR/eIFalpha signaling

(3)

symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity

(3)

symbiont-mediated suppression of host gene expression

(3)

symbiont-mediated suppression of host innate immune response

(3)

symbiont-mediated suppression of host mRNA processing

(3)

symbiont-mediated suppression of host type I interferon-mediated signaling pathway

(3)

Biological cell component  (2)

host cell cytoplasm

(3)

host cell nucleus

(3)

SCOP fold  (1)

Ns1 effector domain-like

(1)

SCOP family  (1)

Ns1 effector domain-like

(1)

CATH class  (2)

Alpha Beta

(26)

Mainly Alpha

(3)

CATH topology  (2)

Nucleotidyltransferase; domain 5

(26)

Helix Hairpins

(3)

Pfam accession / name  (1)

PF00600 : Flu_NS1

(26)

Diffraction protocol  (1)

Single wavelength

(25)

Diffraction radiation source type  (2)

Synchrotron

(13)

Rotating anode

(12)

Diffraction source  (13)

RIGAKU

(6)

RIGAKU MICROMAX-007 HF

(4)

ALS BEAMLINE 5.0.1

(2)

APS BEAMLINE 19-ID

(2)

BESSY BEAMLINE 14.1

(2)

RIGAKU MICROMAX-007

(2)

ALS BEAMLINE 4.2.2

(1)

APS BEAMLINE 21-ID-F

(1)

APS BEAMLINE 22-ID

(1)

BESSY BEAMLINE 14.2

(1)

DIAMOND BEAMLINE I03

(1)

DIAMOND BEAMLINE I04

(1)

NSLS BEAMLINE X25

(1)

Synchrotron site  (5)

APS

(4)

ALS

(3)

BESSY

(3)

Diamond

(2)

NSLS

(1)

Diffraction detector type  (3)

CCD

(14)

Image plate

(4)

Pixel

(1)

Refinement software  (5)

PHENIX

(12)

REFMAC

(10)

BUSTER

(2)

BUSTER-TNT

(2)

CNS

(1)

NMR software packages  (11)

AutoAssign

(1)

AutoStructure

(1)

CNS

(1)

CYANA

(1)

MolProbity

(1)

NMRPipe

(1)

PSVS

(1)

PdbStat

(1)

Sparky

(1)

TALOS

(1)

TopSpin

(1)

NMR Field Strength

500.0 - 600

(1)

600.0 - 700

(1)

700.0 - 800

(1)

800.0 - 900

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%